Broad-Spectrum Herbal Formula
(Anti-inflammatory, Antioxidant and TNF-inhibiting)
Radical Oxygen Species (ROS), elevated TNF-alpha and inflammation are known to play a significant role in many cases of infertility in both men and women.
Radical Oxygen Species (ROS) and Infertility
Radical Oxygen Species (ROS, also called "free radicals") include the hydroxyl radical, hydrogen peroxide, lipid peroxide, hypochlorite, chloramines, superoxide anion, peroxyl radical to name just a few. Inflammation is a primary cause of increased ROS.
In women, Radical Oxygen Species are detrimental to both natural and assisted fertility.1-8 ROS is also associated with polycystic ovarian disease, endometriosis, spontaneous abortions, preeclampsia, hydatidiform mole, embryopathies, preterm labor, and intrauterine growth retardation.2-3
In men, Radical Oxygen Species have been shown to decrease sperm motility and concentration and is associated with male infertility of unknown cause.9-32 ROS in males also damages DNA and should therefore be corrected even when assisted pregnancy is planned.31,36,40 The effect of ROS on male fertility is so well-established that many fertility specialists consider routinely testing for ROS in sub-fertile men.
Tumor Necrosis Factor-alpha (TNF-α) and Infertility
Tumor Necrosis Factor-alpha (TNF-a) is an inflammatory cytokine that stimulates free radical production by mitochondria. Don't let the term "tumor" alarm you; everyone has TNF-α in their body. Excessive amounts of TNF-α impair fertility.
In women, high TNF-α suppresses ovarian function, increases Natural Killer cells (NK cells) and is associated with infertility. High TNF-α is also associated with recurrent spontaneous abortion.
In men, high TNF-α is associated with decreased sperm count and motility.20
Read more about inflammatory cytokines: Cytokines: A Simplified Look At Messenger Molecules
Broad-Spectrum Herbal Formula
Maxi Flavone is a broad-spectrum herbal antioxidant formula that affords protection from multiple ROS species, lowers TNF-alpha and is anti-inflammatory. Flavonoid-containing herbs have a synergistic effect when used in combination.41,71
Maxi Flavone supplies therapeutic doses of the most well-studied flavonoid herbs including:
I.) Pycnogenol (Pinus maritima) antioxidant and antiinflammatory effects. Please see the extensive reference list elsewhere on this website:
Grape Seed Extract and Pycnogenol
II.) Red Grape Seed (Vitus vinifera) with seeds, skin and stems which therefore contains Resveretrol. Both have potent antioxidant and anti-inflammatory effects. Resveretrol also suppresses TNF-α.72 Please see the extensive reference list elsewhere on this website: Grape Seed Extract
III.) Bilberry (Vaccinium myrtillus), the most potent of the edible berries (39), has significant antioxidant and anti-inflammatory properties 41-43,73-7. Bilberry inhibits TNF-α43 , lipid peroxidation73-74 and is an active radical scavenger of H2O242,76, superoxide and peroxynitrite.41
IV.) Green Tea (Camillia sinesis) is an antioxidant that suppresses TNF-α.44-48 It has been shown to cause regression of endometriosis in animal models.49-50
V.) Ginkgo (Ginkgo biloba) is an antioxidant that has TNF-α suppressing properties.51-57 Ginkgo raises the radical-scavenging enzymes glutathione, SOD and catalase.51-52 It has also been shown to relieve symptoms of congestive PMS.56
VI.) Milk Thistle (Silybum marianum) is an antioxidant and antiinflammatory59-63 that significantly inhibits TNF-α. 58-61,63 It has been shown to modulate immune response in vivo.60
VII.) Citrus Bioflavonoids (with hesperidin, narginen and other flavonoids) have antioxidant64-67,69, antiinflammatory58,60,64,66, and TNF-a inhibiting properties.64
Why Reproductive Immunologists Recommend Maxi Flavone™
Maxi Flavone is a state-of-the-art formulation of flavonoid-containing herbs with synergistic effects specific to fertility enhancement. Only full-spectrum extracts, not isolated flavonoids are included, thus preserving the synergistic activity of all naturally-occurring phytonutrient compounds.
Maxi Flavone contains optimal doses of the flavonoid herbs which quench Radical Oxygen Species (ROS), lower TNF-α and NK cell activity (only when excessive) and decrease excess inflammation.
In addition to the beneficial effect on fertility, these herbs also have numerous beneficial effects on overall health. Maxi Flavone™ is a potent formula providing support for immune function, circulatory health, liver detoxification mechanisms, and antioxidant pathways.
Read more about Maxi Flavone and Interleukin 6 (IL-6) here:
Using Flavones to Lower IL-6: Which is better - Luteolin / Diosmin or Maxi Flavone?
Suggested Dose for Fertility:
Women: 1 capsule per day with a meal.
Men: 1 capsule, 2 times per day with meals.
NOTE: Two capsules of Maxi Flavone™ is equivalent to 10 to 12 tablets or capsules of individual extracts taken separately, resulting in significant cost savings.
Due to strong interest in this formula we may occasionally become backordered, with shipping delayed by up to a week.
Because of this we recommend that our Maxi Flavone customers consider ordering two bottles, re-order when they have completed the first bottle and never worry about running out of this important flavonoid / antioxidant / TNF-inhibiting formula.
For our fertility patients and customers, Dr. Myatt recommends that this formula be continued through conception and for the duration of pregnancy.
Product # F307 (60 Caps) $46.95 - Enter Quantity Desired and Click "Add To Cart" Button
(Please note: there have been rare reports of this item refusing to "add to cart" - especially for iPad / i phone users - and we are working to find the problem - if this happens to you, please just call us and we'll be happy to take your order - 1-800-376-9288)
Yes, we can ship to Great Britain. Please contact us for details.
What some Maxi Flavone users have said:
We have come across some user experiences on the fertility forums. We do not know these people, and we are not associated with them in any way except that they have purchased Maxi Flavone from us (we are the only place to obtain it) so these comments are just captures from the open internet.
From a Yahoo! Immunology Support group; You buy it online…found it by research only and I think someone once mentioned it here. It was not prescribed or recommended by anyone but myself! No prescription needed…all herbs and antioxidants. Just google Maxi Flavone and Dr. Myatt and it will come up. My cytokines were lowered in just one month!
And another Post on the Yahoo! Immunology Support group; After getting my order of MaxiFlavone (I had run out a couple of times and was too confident!) I resumed taking it and tested again , I used to test every 4 weeks and then now every 2 weeks but won’t be testing anymore this year because I have a different insurance. Anyway, after taking and retesting again my levels ALWAYS went back to normal. I have taken it 70-80% of my pregnancy. I continue to take it now. Intralipds may often raise cytokines, everyone is different, and at that time when they spiked after intralipid or pregnancy???? I had IVIG and then MaxiFlavone for maintenance.
I use Wobenzyme for my NK’s…which have stayed in range after IVIG almost whole pregnancy except for now…my problem was with cytokines spiking the three times I stopped taking MaxiFlavone. Coincidence????? I have come to the conclusion that MaxiFlavone REALLY does work! J
A post on a Conception Support website: I have chronic inflammation from my endometriosis. I recently started a vitamin endorsed by a well known reproductive immunologist called Maxi Flavone. Within 2 days I was off my pain killers and if I miss my dose of the Maxi Flavone by even an hour the inflammation comes back, but once I take it again it disappears soon after. If there's any sort of suspected autoimmune issues it'll support that as well.
| Serving Size 1 Capsule (60 Caps per bottle)
|Amount Per Capsule
||% Daily Value
|Pycnogenol®** Pine Bark (Pinus maritima) dried extract
|| 5 mg
|Red Grape (Vitis vinifera) seeds, skin, and stems, dried extract with resveratrol
|| 100 mg
|Bilberry (Vaccinum myrtillus) fruit, dried extract, min. 25% anthocyanosides
|| 60 mg
|Green Tea (Camellia sinensis) leaf, dried extract, min. 50% catechins (polyphenols)
|| 180 mg
|Ginkgo (Ginkgo Biloba) leaf, dried extract, min. 24% ginkgo flavone glycosides and 6% terpene lactones
|| 40 mg
|Milk Thistle (Silybum marianum) fruit, dried extract, min. 80% silymarin
|| 100 mg
|Citrus Bioflavonoid Complex, min. 50% bioflavonoids
|| 125 mg
* Daily value not established
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