AND Reversal with "The Forgotten Mineral"
Strontium, a naturally occurring mineral in the same mineral family as calcium and magnesium, has been shown to promote bone growth in both human and animal studies. Strontium occurs in nature in soil, foods, and bones.
Before you get nervous, let's clarify something: this is NOT the radioactive "strontium 90" that many of us were forced to hide from under our desks in the 1950s during "A-bomb drills." The strontium I'm talking about is an all-natural, non-radioactive mineral that is quite safe.
Strontium has been studied since the early 1900's for its effect on bone density. Strontium and calcium have been shown to be superior to calcium alone for rebuilding bone.
A Mayo Clinic study conducted in 1959 looked at 22 individuals with severe (and painful) osteoporosis. Part of the group took 1,700 milligrams of strontium daily. Another group took the same amount of strontium with estrogen and testosterone. In the "hormones plus strontium" group, 9 of 10 people experienced marked improvement of their symptoms, and the other one had moderate improvement. In the strontium-only group, 18 of 22 had marked improvement and the other four had moderate improvement. Bottom line: every person in this study had moderated to marked improvement using strontium.
Another study in 1979, performed on a group of patients with metastatic bone cancer (cancer that has spread to bone), showed an improvement in bone density and decreased bone pain in the strontium-treated group.
In 1985, another study found that "Following strontium therapy, all [measurements] of bone formation increased, while bone resorption remained unchanged." Sixteen years later, a research group reviewed the studies on strontium and concluded that "In addition to its anti-resorptive activity, strontium was found to have anabolic (tissue-building) activity in bone."
These studies have used strontium citrate, strontium carbonate, strontium lactate and strontium gluconate. All forms of strontium have produced positive effects, indicating that it is the strontium itself that is active and not what it is bound to. There is some evidence that strontium citrate is more bioavailable. Why do I mention this little "factoid?" So that Big Pharma can't fool you into buying an expensive drug form of strontium when a simple supplemental form works as well.
Naturally, the most recent strontium-osteoporosis research has been performed by a drug company using a patentable strontium combination. (Remember, strontium by itself isn't patentable because it is a naturally-occurring substance). But combined with a synthetic substance called ranelic acid, strontium becomes a patentable drug. This "drug" is available in Europe as the trademarked Protos®, but all studies before this suggest that it is the strontium itself which is responsible for bone-building effects.
In a three-year, randomized, double-blind, placebo controlled study using 680 milligrams of strontium daily, women suffering from osteoporosis had a 41 percent reduction vertebral fractures compared with placebo. The overall vertebrae density in the strontium group increased by 11.4 percent compared to a 1.3 percent decrease in the placebo group.
In another recent study, 353 women who had already experienced at least one osteoporosis-related vertebral fracture took varying levels of strontium ranelate or a placebo. In the group who tool 680 milligrams of strontium daily, there was a 3% increase in lumbar bone mineral density per year, significantly greater than placebo. At the end of the second year of the study, there was a significant decrease in fractures in the strontium group compared to placebo.
In a 2002 randomized, double-blind, placebo-controlled trial, 160 post-menopausal females who did not have osteoporosis were asked to take placebo or varying amounts of strontium daily. Compared to the placebo group, women who took 340 milligrams strontium a day had a significant increase in bone mineral density in two years' time. All groups also took 500 milligrams of calcium daily, but no hormones or vitamin D.
It appears that not only can strontium prevent osteoporosis, it can repair existing damage. And it doesn't seem to matter what form it is in: strontium ranelate (a patented drug in Europe), strontium citrate, strontium gluconate, strontium lactate, or strontium carbonate. It's the mineral strontium itself that works the magic on bone!
Sources of Strontium
Bad news: there's not enough strontium in food to have a significant effect if you already have osteoporosis. If you have a diagnosis of osteoporosis, you should take strontium in supplement form. If you don't currently have osteoporosis, then eating plenty of food high in strontium "may" be enough to protect you. Foods high in strontium include spices, seafood, whole grains, root and leafy vegetables, and legumes.
If you want to be on the safe side concerning osteoporosis prevention, consider taking one dose of strontium (200-400mg) per day. For those without osteoporosis but with known risk factors (family history, immobility, smoking, etc.) one capsule twice daily is prudent. Also be sure to take the recommended calcium (1,200-1,500 milligrams for post-menopausal females) plus associated bone nutrients including magnesium, zinc, boron and vitamin D.
NOTE: Maxi Multi does not contain strontium. If you see a "bone formula" with strontium, don't take it. Strontium should be taken away from calcium and magnesium for best absorption.
Recommendations: 2 capsules daily. Studies suggest, that for better bioavailability, Strontium should be taken more than two hours before or two hours after taking a calcium supplement. Strontium is absorbed using calcium transport mechanisms, and should not be taken at the same time as calcium supplements.
Each (one) capsule contains: Strontium citrate 340 mg
Other Ingredients: vegetable cellulose capsules, cellulose powder, vegetable source magnesium stearate.
Product # 287 (60 Capsules) $24.95
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1.) Strontium Ranelate Reduces the Risk of Nonvertebral Fractures in Postmenopausal Women with Osteoporosis: Treatment of Peripheral Osteoporosis (TROPOS) Study. J Clin Endocrinol Metab. 2005 May; 90(5):2816-22. Epub 2005 Feb 22.
2.) Picking a bone with contemporary osteoporosis management: Nutrient strategies to enhance skeletal integrity. Clinical Nutrition (Epub ahead of print, 2006 October 12).
3.) The effects of strontium ranelate on the risk of vertebral fracture in women with postmenopausal osteoporosis.” New England Journal of Medicine 350 (2004):459 - 68.
4.) Strontium ranelate reduces the risk of nonvertebral fractures in postmenopausal women with osteoporosis: Treatment of Peripheral Osteoporosis (TROPOS) study. Journal of Clinical Endocrinology and Metabolism 90 (2005):2816 - 22.
5.) Strontium in Finnish foods. International Journal for Vitamin and Nutrition Research 52 (1982): 342 - 50.
6.) Gaby AR. Preventing and Reversing Osteoporosis. Rocklin, CA: Prima Publishing, 1994, 85–92 [review].
7.) Strontium ranelate: a dual mode of action rebalancing bone turnover in favour of bone formation. Curr Opin Rheumatol. 2006 Jun;18 Suppl 1:S11-5.