Category: Health Concerns

B Vitamins

The “Energy Vitamins”

B vitamins comprise an entire complex or “family” of related but different vitamins. Together, the B vitamins comprise an important group of vitamins with many functions, as seen in the chart below. Although their individual functions differ, all B vitamins are involved in energy production in the body. Deficiencies of B vitamins are common today due to food processing.

B vitamin supplementation is useful for:

  • chronic fatigue
  • overweight and obesity
  • memory loss
  • heart disease
  • depression
  • cataracts
  • neuropathy
  • irritability
  • atherosclerosis
  • anemia and more (see chart below).

Maxi Multi is a comprehensive multi-vitamin and mineral formula that includes high potency B complex vitamins. Click here for a full description of this supplement.

B-12 Extreme

The Most Potent B-12 Formula Available.
A full description of B-12 Extreme can be found here.

B-Complex 50

High-potency vitamin B complex in a hypoallergenic, yeast-free formula.

Each (one) capsule contains:

Vitamin B-1 (Thiamine HCL) 50 mg Biotin 50 mg Vitamin B-2 (Riboflavin) 50 mg Pantothenic acid 50 mg Niacinaminde 50 mg Vitamin B-10 (Para-Aminobenzoic Acid) 50 mg Vitmin B-6 (Pyridoxine HCL) 50 mg Choline (Bitartrate) 50 mg Folic Acid 400 mcg Inositol 50 mg Vitamin B-12 (Cyanocobalamine) 50 mcg

Order B-Complex 50 (100 Capsules) Here $15.90

Hi-B-12/Foliplex

High potency sublingual tablet supplying vitamin B-12 and folic acid.

Each (one) capsule contains:
Vitamin B-12 2500 mcg (Cobalamine concentrate)
Folic Acid 800 mcg

Order Hi-B-12/Foliplex (60 tablets) Here $17.00

The B Vitamin Complex “Family”

vitamin major functions major deficiency associations optimal adult dose range best food sources cautions/
notes

vitamin B1
(thiamine)

energy processes fatigue, mental confusion, neuropathy 5-100 mg eggs, berries, nuts, legumes, liver, yeast Nontoxic.

vitamin B2
(riboflavin)

energy processes, wound healing, activates other B vitamins infection, cataracts, blurred vision, eye surgery 5-100 mg green leafy vegetables, eggs, organ meats Nontoxic. Higher doses will make urine a harmless, bright yellow.

vitamin B3
(niacin)

energy processes depression, tension headaches, memory loss 20-100 mg milk, eggs, fish, whole meal wheat flour Doses greater than 50mg may cause a skin flush. Take high doses only with doctors supervision.

vitamin B5
(pantothenic acid)

energy processes; adrenal gland function allergies, morning stiffness; fatigue; muscle cramps 10-1,000 mg eggs, yeast, liver No known toxicity.

vitamin B6
(pyridoxine)

energy processes; antibody formation insomnia, irritability, atherosclerosis 5-200 mg wheat germ, yeast, whole grains Oral contraceptive use increases need for this vitamin.

Folic acid

red blood cell formation, RNA/DNA synthesis fatigue, depression, atherosclerosis 200-800 mcg beans, green leafy veggies, yeast Do not take with Phenobarbital or dilantin.

vitamin B12

red blood cell formation; energy processes atherosclerosis, memory loss, GI symptoms 10-1,200 mcg fermented soy products; root veggies Nontoxic.

Biotin

energy processes; blood sugar regulation muscle pain, depression 300-600 mcg egg yolks, whole wheat No known toxicity.

Basic Advice

A Short Poem Of Medical Advice

Basic Advice

by

Dr. Dana Myatt

I went to the doctor because I was ill
and asked her to give me the miracle pill
to make me feel better – and please, real quick.
You see, I just hate it whenever I’m sick.

She said “I’m afraid your cure is quite up to you.
Your body is sick from the things that you do.
Your diet’s abhorrent – it’s really quite dire.
And by smoking, your lungs think your house is on fire.

Pushing a pencil is exercise – not,
and the stress that you’re under just thickens the plot.
An antibiotic will not cure your cold
which is caused by a virus – this story’s quite old.”

Somewhere in my head this all made good sense;
however, I put up my strongest defense.
“I can’t change my diet ’till after next week.
My friend’s getting married – you know I must eat.

And life’s too stressful to stop smoking now.
If I quit, and start eating, I’ll gain weight and how!
And if I gain weight I’ll feel even worse.
My fat’s not my fault – it’s an old family curse.

And doctor you really just can’t understand
the pace of my life and how busy I am.
I can’t exercise – I haven’t the time.
So I have a few vices. Is that such a crime?

It was Joe in the office who gave me this cold
or else I’m allergic to house dust and mold.
So please give me something to help me feel better.
I’ll follow your instructions right down to the letter.

“I see,” said the doctor, “I’m not getting through.
Here’s a bottle of pills. Four times daily take two.”
“Four times is a lot when my schedule’s so tight.
Can I just take them twice, each morning and night?”

“Do whatever you want” said the doc with a sigh.
I thought for a moment she was going to cry.
“The state of your health is quite up to you
I can counsel and guide you, but you have to choose.

My studied opinion, my highest advice, is
get ‘back to the basics’ – don’t even think twice.
The choices you make will determine your fate.
Improve your condition before it’s too late.

Pills can be helpful and sometimes can cure,
but your daily routine will affect you for sure.
Now pull out your wallet and pay me my fee.
My advice may be basic, but it doesn’t come free!”

Bio-Identical Hormone Therapy

Bio-identical (Natural) Hormone Replacement Therapy
and Other Natural Hormone-Balancing Therapies

Which One is Right for You?

Index:

Are Your Symptoms Cause by Low or Imbalanced Hormones?

What is Bio-identical Hormone Replacement Therapy (bHRT)?

What are the advantages of bHRT?

Delivery System: Oral Versus Transdermal Hormones

How Best to Address Your Menopausal Symptoms and Concerns?

Dr. Myatt’s “Hormone Balance” Programs: Which One is Right for You?

Are Your Symptoms Caused by Low or Imbalanced Hormones?

Women and men both go through “the climacteric,” a period in mid-life when sex hormone production declines.

In women, this change is called “menopause.” In men, the change is often referred to as “andropause.” Many symptoms of the climacteric are similar in men and women.

In women, peri-menopause (“around the time of menopause”) symptoms can include mood swings, weight gain, fatigue, hot flashes, breast tenderness, vaginal dryness, decreased libido (sex drive), urinary leakage or urgency and sleep difficulties. Menstrual periods may becomes less frequent, irregular and farther apart OR they can become heavier and more frequent. Peri-menopause usually begins in a woman’s 40’s but can start as early as the 30’s or as late as the 50’s.

Menopause symptoms in women are similar to peri-menopause symptoms except that menstrual periods cease. Headaches, heart palpitations, cognitive decline and difficulty sleeping may also occur. Bone mineral loss is often accelerated during this time, leading to osteoporosis.

Andropause symptoms in men can include include night sweats, low libido (sex drive), weight gain, depression, anxiety, hot flashes, gynecomastia (enlarged male breasts), fatigue, irritability, and weight gain. Other male climacteric symptoms include erectile dysfunction, loss of stamina and lean muscle mass, cognitive decline and decreased bone mineral density. Men with lower testosterone have a higher risk of coronary artery disease. (1-4)

The change in men is more gradual than in women and symptoms are often attributed to “natural aging” instead of hormone decline.

What is Bio-identical Hormone Replacement Therapy (bHRT)?

Bio-identical Hormone Replacement Therapy (bHRT) is a way to resolve symptoms and/or restore sex hormones to more youthful levels using hormones that are identical to those produced by the human body. Bio-identical hormone replacement therapy (bHRT) differs from convention HRT (cHRT) which uses horse estrogens (Premarin = Pregnant Mares Urine), synthetic and semi-synthetic hormones that are different from human hormones.

Proponents of bHRT believe that many of the unwanted side effects of conventional HRT are due to the “foreignness” of the molecules, not to hormone replacement therapy itself. This may make bHRT a safer form of hormone replacement therapy. (5-10)

How is Bio-Identical HRT Different from Conventional HRT?

Bio-identical hormone replacement is different from conventional HRT in the following ways.

  1. “Identical to human” hormones are used in bHRT. Conventional HRT typically uses horse hormones and synthetic and semi-synthetic hormones. These hormones are not the same molecules as those produced by the human body.It should be noted that there are bio-identical FDA approved hormones available by prescription. Not all “bio-identical” hormones need to be “compounded,” or made up individually by a compounding pharmacist.
  2. Based on Testing. bHRT is prescribed based on individual hormone test results. Conventional HRT does not use testing but bases treatment on improvement of symptoms.
  3. “Pulsed dosing” is often used in bHRT to duplicate the natural rhythm of hormone production and release. Some studies have shown this pattern of use to be safer and just as effective as continuous HRT. (11-12) Conventional HRT typically uses continuous doses of hormones. Continuous doses are associated with higher risk of breast cancer in some studies. (13)

What are the advantages of bHRT?

Is bHRT Safer than conventional HRT?

Conventional hormone replacement therapy, especially in women, is associated with a number of increased health risks including heart disease, stroke, breast cancer, deep vein thrombosis, gallbladder disease and acid reflux. (14-20) Conventional HRT decreases the risk of osteoporosis and can alleviate some symptoms of menopause including hot flashes and vaginal dryness (21-22) but many experts do not believe these improvements justify the increased risks.

Proponents of bio-identical hormone replacement therapy believe that bHRT is safer than conventional hormone therapy and some studies have shown this. (5-10) However, the number of studies done with bHRT is small compared to the studies done with conventional HRT. Large-scale studies of safety and efficacy of bHRT are lacking.

In spite of a small number of studies confirming safety and efficacy, the case for bio-identical hormones also makes sense in theory. Consider these facts:

Conventional hormone replacement therapy typically employs estrogens from pregnant mare’s urine. Horse hormones are significantly different than human hormones. Conventional hormone replacement also typically uses synthetic progesterone. The difference in synthetic and bio-identical progesterone is  significant. It is therefore believed that most if not all of the negative side effects of conventional hormone replacement is due to their “foreign to humans” molecular structure, not to hormone replacement itself. Some studies on bio-identical versus non-bio-identical progesterone confirm that there is a different effect in humans with natural progesterone appearing to have less risk of associated cancers. (5-10)

Further, conventional hormone replacement is almost always prescribed as a “one-size-fits-all” recommendation without the use of any laboratory testing to verify hormone levels. Practitioners of bio-identical hormone replacement typically start with blood, saliva or urine hormone testing and customize hormone prescriptions based on an individual’s unique requirements. Testing can help guide the prescription and prevent levels of hormones from being excessive.

Finally, risks associated with hormone therapy can be monitored, but this is rarely if ever done in conventional hormone prescribing. However, risks such as total hormone levels, ratios of hormones to each other and hormone metabolites can be potent predictors of heart disease and cancer risks. Even without hormone replacement therapy, these risk factors may be worth monitoring in all middle-aged men and women.

To answer the question of safety, there are theoretical reasons to believe that bio-identical HRT should be safer than conventional HRTand some actual studies show better safety.

Is bHRT Effective?

Studies have verified the effectiveness of bHRT for relieving many of the symptoms of menopause. (7-9, 23-24)

My personal clinical experience over the past 23 years is that bHRT can achieve every positive effect that conventional HRT achieves with less risk of negative side effects. Because I monitor risk factors, I have also seen reductions in cardiac and cancer risk markers and improvements in bone mineral density.

Is bHRT Proven?

Studies have demonstrated the effectiveness of bio-identical hormone replacement therapy. (7-9, 23-28)

Anti-Aging Claims for bHRT

Proponents of bHRT claim that keeping hormones at “youthful” levels can extend life expectancy and help delay the effects of aging. These claims have been popularized by public figures like Suzanne Somers in her book “The Sexy Years.” In spite of these claims, there is no proof that continued use of sex hormones, especially estrogen and progesterone in women, have-extending properties. There IS evidence that DHEA in both men and women (25-28) and testosterone in men (29-33) may have a positive influence on health, longevity and hormone balance.

While claims of living better and longer with bHRT are numerous, proof is lacking. This leaves bHRT and its anti-aging effects in the realm of theory at this point.

Delivery System: Oral Versus Transdermal Hormones

In addition to the “form” (natural or synthetic) of hormone, the method of administration has been shown to make a significant difference in safety and efficacy.

Orally administered hormones, especially estrogens, can increase risk of blood clots and deep vein thrombosis, increase hs-CRP (a marker of inflammation), decrease free testosterone and thyroid hormone and increase cortisol.(34) Oral estrogen is also associated with an increased risk of gallbladder disease and acid reflux. (15,18)

Many hormones used transdermally — applied to the skin or mucous membranes — do not appear to have these unwanted effects. (35) Therefore, when considering bHRT, the form that it is used in is also of importance.

How Best to Address Your Menopausal Symptoms and Concerns?

Symptoms of peri-menopause and menopause in women and andropause in men are a sign from the body that something is “off kilter.” For example, hot flashes in women correspond to an increase in oxidative stress and decreased nitric oxide levels (NO), both risk factors for cardiovascular disease. (36-37)

These symptoms and resulting negative physical changes are not an inevitable part of aging and should not be ignored. They can be addressed and improved through a variety of means, including but not limited to bio-identical hormone replacement therapy.

Diet changes, exercise and personal health practices can all help to improve symptoms of menopause and andropause. (38-39) There are nutritional and herbal supplements are proven to help correct menopause and andropause symptoms. (40-42)  Bioidentical hormone replacement is one way to address declining hormone levels, but it is not the only way.

The decision to use bHRT is a personal one that should be made in conjunction with an holistic physician. Your degree of symptoms, personal thoughts about bHRT, willingness to make other lifestyle changes and use nutritional and herbal supplements should all factor into the “decision equation.” Here are some additional factors to consider when making this decision.

Possible “Pro’s” of bHRT

  1. Faster. Herbs and other factors can help balance hormones, but the effects of bHRT might be more dramatic and faster. (NOTE: I cannot find scientific studies to support this; it is my clinical observation — Dr. Myatt)
  2. Easier. Taking an Rx. may be easier than making lifestyle changes, although any good holistic physician should recommend positive lifestyle changes as part of an overall health program.
  3. Safer. Some studies point to the improved safety of bHRT over conventional HRT. (14-20)
  4. Better hormone balance. Some hormones such as DHEA and testosterone have independent health benefits. (25-33, 43) These hormones are typically not used in conventional HRT but may be prescribed by a physician who uses bHRT.

Possible “Cons” of bHRT

  1. Cost. bHRT is not necessarily expensive and can be as little as $30/month depending on what hormones are needed. However, an Rx. will represent an ongoing expense. Most practitioners prescribing bHRT require initial hormone testing (to customize your Rx.) and follow-up testing to ensure that your hormones are at optimal (safe and effective) levels. Testing plus the Rx. itself will be an ongoing expense.
  2. Safety. Although bHRT appears safer than conventional HRT, there is some evidence that no type of hormone replacement in women has been proven to be “protective” or safer than natural menopause.

Alternatives to bHRT

Hormone Testing: Saliva vs. Blood vs. Urine

Conventional hormone replacement does not use testing. The recommended “end point” (goal of treatment) is alleviation of symptoms. Therefore, when a woman has stopped having hot flashes, for example, the dose is considered to be correct.

Most bHRT practitioners begin treatment with some form of hormone testing, using either saliva, blood or urine to evaluate hormone levels. Although there are many claims about the superiority of one form of testing over another, scientific studies are lacking.

Saliva testing is the least accurate measure of sex hormones. Numerous studies have failed to find a reliable correlation between saliva hormone levels and physiologic (body) hormone levels with the exception of cortisol measurement. (17,44-54)

Blood testing does not reveal the hourly variation and 24-hour cyclical nature of hormone release but it has been better studied. For this reason, blood testing is probably the second-best method of hormone testing.

Twenty-four hour urine testing may be the preferred method of hormone testing. In addition to evaluating hormone output including the 24-hour variation (a “video” instead of a “snapshot,”), urine testing also looks at biochemical intermediates which are independent indicators of hormone levels and hormone metabolism. Some intermediates, such as the 2:16alpha-hydroxyestrone ratio, may be potent predictors of increased risk for hormone-related cancers. (55-56) Fortunately, once known, these risks can be modified.

Dr. Myatt’s Hormone Balance Programs:
Which One is Right for You?

All bHRT programs in both men and women begin with a Brief Telephone Consultation. Together, we determine which program is right for you.

Depending on your age, symptoms, beliefs and what you hope to achieve, we work together to design and implement a complete program to optimize both hormone balance and overall health.

For some men and women, this will include the use of bio-identical hormone replacement therapy, as determined by laboratory testing (24-hour urine). The form may differ depending on which hormones are needed, but usually include both transdermal and oral hormone replacements.

Hormone balance and relief of symptoms can often be achieved without the use of hormone replacement therapy. The decision to use hormones should not be taken lightly and should be made in consultation with a physician who is well-versed in both bHRT and non-hormonal methods of achieving hormone balance.

Which Hormone-Balancing Program is Right for You ?

 The Bronze program is for:

• Peri-menopausal women
• Post-menopausal women
• Men over 35

For women and men desiring better hormone balance  without  the use of
bio-identical hormone replacement.

You will receive a Personalized Health Report and Phone Follow-Up of 60 mins

The Silver program is for:

• Peri-menopausal women
• Post-menopausal women
• Men over 35

For women and men desiring better hormone balance AND bone mineral density protection without using
bio-identical hormone replacement.

You will receive a Personalized Health Report and Phone Follow-Up of 120 mins

The Gold program is for:

• Peri-menopausal women
• Post-menopausal women
• Men over 35

For women and men desiring sex hormone optimization and breast/prostate cancer risk reduction using bHRT.

You will receive a Personalized Health Report and Phone Follow-Up of 360 mins

The Platinum program is for:

• Peri-menopausal women
• Post-menopausal women
• Men over 35

For women and men desiring anti-aging, full-scope endocrine balancing (including sex, thyroid and adrenal hormones) and
breast /prostate cancer risk reduction using bHRT.

You will receive a Personalized Health Report and unlimited Phone Follow-Up

 * saliva hormone testing not available in New York state.

References

1.) Corona G, Rastrelli G, Monami M, Guay A, Buvat J, Sforza A, Forti G, Mannucci E, Maggi M.
Hypogonadism as a risk factor for cardiovascular mortality in men: a meta-analytic study.
Eur J Endocrinol. 2011 Nov;165(5):687-701. Epub 2011 Aug 18.

2.) Corona G, et al “Low testosterone is associated with an increased risk of MACE lethality in subjects with erectile dysfunction” ECE 2010; Poster 149.

3.) Ohlsson C, Barrett-Connor E, Bhasin S, Orwoll E, Labrie F, Karlsson MK, Ljunggren O, Vandenput L, Mellström D, Tivesten A.High Serum Testosterone Is Associated With Reduced Risk of Cardiovascular Events in Elderly Men, J Am Coll Cardiol, 2011; 58:1674-1681

4.) Tivesten A, Mellström D, Jutberger H, Fagerberg B, Lernfelt B, Orwoll E, Karlsson MK, Ljunggren O, Ohlsson C. Low serum testosterone and high serum estradiol associate with lower extremity peripheral arterial disease in elderly men. The MrOS Study in Sweden. J Am Coll Cardiol. 2007 Sep 11;50(11):1070-6. Epub 2007 Aug 24.

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20.)  [No authors listed] Breast cancer and hormone replacement therapy: collaborative reanalysis of data from 51 epidemiological studies of 52,705 women with breast cancer and 108,411 women without breast cancer. Collaborative Group on Hormonal Factors in Breast Cancer. Lancet. 1997 Oct 11;350(9084):1047-59.

21.) de Villiers TJ, Stevenson JC. The WHI: the effect of hormone replacement therapy on fracture prevention. Climacteric. 2012 Jun;15(3):263-6.

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23.)  Cramer EH, Jones P, Keenan NL, Thompson BL. Is naturopathy as effective as conventional therapy for treatment of menopausal symptoms? J Altern Complement Med. 2003 Aug;9(4):529-38.

24.)  Ruiz AD, Daniels KR, Barner JC, Carson JJ, Frei CR. Effectiveness of compounded bioidentical hormone replacement therapy: an observational cohort study. BMC Womens Health. 2011 Jun 8;11:27.

25.) Genazzani AR, Pluchino N, Begliuomini S, Stomati M, Bernardi F, Pieri M, Casarosa E, Palumbo M, Genazzani AD, Luisi M. Long-term low-dose oral administration of dehydroepiandrosterone modulates adrenal response to adrenocorticotropic hormone in early and late postmenopausal women. Gynecol Endocrinol. 2006 Nov;22(11):627-35.

26.) Labrie F. DHEA, important source of sex steroids in men and even more in women.
Prog Brain Res. 2010;182:97-148.

27.) Pluchino N, Ninni F, Stomati M, Freschi L, Casarosa E, Valentino V, Luisi S, Genazzani AD, Potì E, Genazzani AR. One-year therapy with 10mg/day DHEA alone or in combination with HRT in postmenopausal women: effects on hormonal milieu. Maturitas. 2008 Apr 20;59(4):293-303. Epub 2008 Apr 3.

28.) Stomati M, Monteleone P, Casarosa E, Quirici B, Puccetti S, Bernardi F, Genazzani AD, Rovati L, Luisi M, Genazzani AR. Six-month oral dehydroepiandrosterone supplementation in early and late postmenopause. Gynecol Endocrinol. 2000 Oct;14(5):342-63.

29.) Aaronson AJ, Morrissey RP, Nguyen CT, Willix R, Schwarz ER. Update on the safety of  testosterone therapy in cardiac disease. Expert Opin Drug Saf. 2011 Sep;10(5):697-704. Epub 2011  Mar 22.

30.) De Maddalena C, Vodo S, Petroni A, Aloisi AM. Impact of testosterone on body fat composition. J Cell Physiol. 2012 Apr 11. doi: 10.1002/jcp.24096. [Epub ahead of print]

31.) Toma M, McAlister FA, Coglianese EE, Vidi V, Vasaiwala S, Bakal JA, Armstrong PW, Ezekowitz  JA. Testosterone supplementation in heart failure: a meta-analysis. Circ Heart Fail. 2012 May

32.) Vermeulen A. Ageing, hormones, body composition, metabolic effects. World J Urol. 2002 May;20(1):23-7.

33.) Vermeulen A, Goemaere S, Kaufman JM. Testosterone, body composition and aging. J Endocrinol Invest. 1999;22(5 Suppl):110-6. 1;5(3):315-21. Epub 2012 Apr 17.

34.)  Shifren JL, Desindes S, McIlwain M, Doros G, Mazer NA. A randomized, open-label, crossover study comparing the effects of oral versus transdermal estrogen therapy on serum androgens, thyroid hormones, and adrenal hormones in naturally menopausal women. Menopause. 2007 Nov-Dec;14(6):985-94.

35.)  L’hermite M, Simoncini T, Fuller S, Genazzani AR. Could transdermal estradiol + progesterone be a safer postmenopausal HRT? A review. Maturitas. 2008 Jul-Aug;60(3-4):185-201. Epub 2008 Sep 5.

36.) Leal M, Díaz J, Serrano E, Abellán J, Carbonell LF. Hormone replacement therapy for oxidative stress in postmenopausal women with hot flushes. Obstet Gynecol. 2000 Jun;95(6 Pt 1):804-9.

37.) Leal Hernández M, Abellán Alemán J, Carbonell Meseguer LF, Díaz Fernández J, García Sánchez FA, Martínez Selva JM. Influence of the presence of hot flashes during menopause on the metabolism of nitric oxide. Effects of hormonal replacement treatment]. Med Clin (Barc). 2000 Jan 22;114(2):41-5.

38.) North American Menopause Society. Treatment of menopause-associated vasomotor symptoms: position statement of The North American Menopause Society. Menopause. 2004 Jan-Feb;11(1):11-33.

39.) McKee J, Warber SL. Integrative therapies for menopause. South Med J. 2005 Mar;98(3):319-26.

40.) Low Dog T. Menopause: a review of botanical dietary supplements. Am J Med. 2005 Dec 19;118 Suppl 12B:98-108.

41.) Kronenberg F, Fugh-Berman A. Complementary and alternative medicine for menopausal symptoms: a review of randomized, controlled trials. Ann Intern Med. 2002 Nov 19;137(10):805-13.

42.) Geller SE, Studee L.Botanical and dietary supplements for menopausal symptoms: what works, what does not. J Womens Health (Larchmt). 2005 Sep;14(7):634-49.

43.) Øverlie I, Moen MH, Holte A, Finset A. Androgens and estrogens in relation to hot flushes during the menopausal transition. Maturitas. 2002 Jan 30;41(1):69-77.

44.) Gröschl M. Current status of salivary hormone analysis. Clin Chem. 2008 Nov;54(11):1759-69. Epub 2008 Aug 29.

45.) Hagen J, Gott N, Miller DR. Reliability of saliva hormone tests. J Am Pharm Assoc . 2003 Nov-Dec;43(6):724-6.

46.) Davison S. Salivary testing opens a Pandora’s box of issues surrounding accurate measurement of testosterone in women. Menopause. 2009;16:630-631.

47.) Flyckt RL, Liu J, Frasure H, Wekselman K, et al. Comparison of salivary versus serum testosterone levels in postmenopausal women receiving transdermal testosterone supplementation versus placebo. Menopause. 2009 Jul-Aug;16(4):680-8.

48.) Granger DA, Shirtcliff EA, Booth A, et al. The “trouble” with salivary testosterone. Psychoneuroendocrinology. 2004 Nov;29(10):1229-40.

49.) Mörelius E, Nelson N, Theodorsson E. Saliva collection using cotton buds with wooden sticks: a note of caution. Scand J Clin Lab Invest. 2006;66(1):15-8.

50.)  6.Lewis JG. Steroid analysis in saliva: an overview. Clin Biochem Rev. 2006 Aug;27(3):139-46.

51.) Stanczyk FZ, Paulson RJ, Roy S. Percutaneous administration of progesterone: blood levels and endometrial protection. Menopause. 2005 Mar;12(2):232-7.

52.) Lewis JG, McGill H, Patton VM, et al. Caution on the use of saliva measurements to monitor absorption of progesterone from transdermal creams in postmenopausal women. Maturitas. 2002 Jan 30;41(1):1-6.

53.) Wren BG, McFarland K, Edwards L, et al. Effect of sequential transdermal progesterone cream on endometrium, bleeding pattern, and plasma progesterone and salivary progesterone levels in postmenopausal women. Climacteric. 2000 Sep;3(3):155-60.

54.) Wood P. Salivary steroid assays – research or routine? . Ann Clin Biochem. 2009 May;46(Pt 3):183-96. Epub 2009 Jan 28.

55.) Kabat GC, Chang CJ, Sparano JA, Sepkovie DW, Hu XP, Khalil A, Rosenblatt R, Bradlow HL.Urinary estrogen metabolites and breast cancer: a case-control study. Cancer Epidemiol Biomarkers Prev. 1997 Jul;6(7):505-9.

56.) Muti P, Bradlow HL, Micheli A, Krogh V, Freudenheim JL, Schünemann HJ, Stanulla M, Yang J, Sepkovic DW, Trevisan M, Berrino F. Estrogen metabolism and risk of breast cancer: a prospective study of the 2:16alpha-hydroxyestrone ratio in premenopausal and postmenopausal women. Epidemiology. 2000 Nov;11(6):635-40.

Black Salve Intensive

Resources for Students

Hello Doctors, Herbalists and Interested Others!

Here is part of the promised follow-up resources from our Black Salve Intensive.

Please Note:

  • The information on this page is presented for educational purposes only.
  • This information is based on Dr. Myatt’s clinical experience with Black Salve. It is not intended as “how to” instruction for anyone using Black Salve.
  • As Dr. Myatt explained in her lectures, Black Salve is not recommended for the removal of cancers other than melanoma.
  • Removal of any cancer with Black Salve is “Chemical Surgery.” If you would not be comfortable cutting a lesion out with a scalpel then you should not be considering the use of Black Salve.

Malignant melanoma: practice visual diagnosis

Here are slides of melanoma, but also look at their NON-melanoma pages for comparison.

More practice pictures: comparisons of benign and malignant lesions

Remember, the “big deal” in dermatology is whether or not you can visually be sure of a melanoma. “When in doubt, cut it out (biopsy),” which in the case of melanoma means “cut it out with a big margin” (bummer, since most lesions are NOT melanoma)
OR
apply the black salve for 30 minutes and see if the lesion changes. If it does,
something is abnormal. Take it out. Here is what a suspicious lesion will look
like in 20-30 minutes after application of the black salve: (slide from the Black Salve Intensive will go here as soon as we convert the pic to digital!). Visualize that little white bump you saw in several slides at the conference.

Making Black and Other Salves

Black Salve

The primary ingredients in black salve are blood root (sanguinaria) and zinc chloride, although chaparral and other herbs have also been used.

Black Salve Recipe 1 & 2

Drawing Salve

Remember that drawing salves will contain charcoal and usually also bentonite  clay as the main “magic” in the formula.

Drawing salve #1

Healing Salve

Most healing salves contain some variation on a theme of comfrey, aloe vera, or calendula.

Healing salve with comfrey

Make this with chamomile and comfrey

I will post additional recipes as I find them. If any of you discover a good recipe, please forward it to me for addition to this page.

Buying Black and Other Salves

1.) Best on Earth I haven’t used their black salve but it’s got all the right ingredients and looks like it should work. They also have “after care” salve, AKA “healing salve.” They do NOT carry a drawing salve.

I have used their non-toxic sunscreen and I love it! It’s light, non-greasy, feels wonderful on the skin and doesn’t contain any potentially harmful ingredients. I now use this myself for my daily sunscreen (face and neck).

2.) Sun Spot (glycoalkaloid) cream (for non-melanoma — basal cell and squamous cells, actinic keratosies and other “pre-cancerous” lesions).

Misc. Black Salve Information

Ingredients, pictures and history of black salve. This is a great page with pictures and history of each ingredient.

Bone and Joint Health

Arthritis and Osteoporosis are NOT Inevitable

The bones and joints are often some of the first parts of the body to show signs of aging. Contrary to popular belief, however, the “wear and tear” theory of arthritis has been largely disproved. Although an injury can certainly cause joint damage, most causes of arthritis are not related to “overuse” or injury. We know this because senior marathon runners — who place a lot more “wear and tear” on their joints — actually suffer from less arthritis than non-runners of similar age.

If “wear and tear” isn’t the main causes of joint pain, osteoporosis and arthritis, what is? Decreasing male and female sex hormones, lack of bone nutrients, overweight and obesity, lack of exercise and body-wide inflammation and free-radical damage are some of the most common causes of joint pain and chronic changes such as arthritis. Low gastric acidity, common in people over age 50, impairs the body’s ability to assimilate bone nutrients such as calcium from food and supplements. This should be evaluated with a gastric acid self-test.

Here are some of the top recommendations for maintaining or restoring bone and joint health.

Top Bone and Joint Health Supplements and Herbs

Bone and Joint Therapies
Table of Contents

Bone and Joint
Health Concerns by Topic

Multiple Vitamin/Mineral Formula Arthritis-Osteoarthritis Bromelain Arthritis – Rheumatoid Cal-Mag Amino Back Pain COX2 Low Gastric Acidity Vitamin D Menopause, Female DHEA Menopause, Male (Andropause) Gastric Acid Self-Test Osteoporosis Melatonin Male hormones Female hormones Glucosamine sulfate Grape Seed Extract MSM Strontium Turmeric Other

Multi Vitamin/Mineral Formula – Not a “once per day” pill (they don’t contain enough of anything to have any effect except preventing severe deficiency disease). A complete bone and joint-protecting multiple should include optimal doses (not minimal doses) of B complex vitamins, C, D, K, calcium, magnesium, vanadium, zinc, and boron which are all especially important for strong bones.

If you only take ONE NUTRITIONAL FORMULA for your overall health plus bone and joint health, a quality Optimal Multiple Vitamin/Mineral such as Maxi Multi should be The One.

Bromelain Nature’s Premier Anti-Inflammatory herb,
Bromelain is a mixture of sulfur-containing, protein-digesting enzymes from the stem of Anansus cosmosis (pineapple). Since it was introduced as a medicinal agent in 1957, more than 200 scientific papers on bromelain’s medicinal uses have appeared in the medical literature. It is one of the safest, most well-studied anti-inflammatory herbs known.

Cal-Mag Amino The recommended calcium dose for post-menopausal women or for those with osteoporosis is 1,500 mg calcium with corresponding magnesium, boron and vitamin D. Maxi Multi Daily Multiple formula contains 1000 mg of calcium and 500 mg magnesium per day, which is optimal for most people. Post-menopausal women and anyone with a diagnosis of osteoporosis may need even higher doses. Cal-Mag Amino supplies additional calcium, magnesium, vitamin D and boron is easy-to-assimilate forms.

Cox-2-Support A superior anti-inflammatory herbal formula. Why take dangerous NSAID’s for pain relief when you can take safe this and effective combination?

Vitamin D increases calcium absorption. Deficiencies of Vitamin D are associated with osteoporosis, rheumatic pains, and dental disease. Many authorities are recommending that the RDA should be raised from 400 IU to 1,000 IU. Doses of 1,000-2,000 are not only safe, they may be needed for disease prevention.

DHEA is a steroid hormone secreted by the adrenal glands. It is a precursor (“master hormone”) for many other steroid hormones including male and female sex hormones (estrogen and testosterone) and corticosteroids. DHEA levels often decline dramatically with age.

Low DHEA levels in the brain and blood are thought to contribute to many of the problems associated with aging including age-related memory and mental decline, decreased strength and muscle mass, lowered immune system response, heart disease and atherosclerosis, and age-related weight gain.

Gastric Acid Function Studies have shown that stomach acid production declines with age. Why does this matter? Because a strong stomach acid is necessary to assimilate bone nutrients from food and supplements, including calcium and magnesium (the major bone nutrients). Surprisingly, even symptoms of “excess stomach acid” are usually caused by low, not high, stomach acid. Learn more about gastric acid function here.

Natural Hormone Replacement Therapy (estrogen, progesterone, testosterone, pregnenelone) Both women and men appear to benefit from natural hormone replacement therapy after age 40. By “natural,” I mean using hormones that are identical to what the body manufactures and in amounts that a healthy body produces in early adulthood. This is a very different type of hormone replacement from the semi-synthetic forms and doses used in conventional medicine.

Male hormones: testing and replacement

Female hormones: testing and replacement

Glucosamine Sulfate is the only form of glucosamine proven by over 300 scientific investigations and 20 double-blind studies to stimulate joint repair and relieve pain.

Glucosamine is a molecule manufactured by the body. Inside the joint, it stimulates the production of glycosaminoglycans (GAG’s) which are the main structural material of joints. Studies suggest that a decline of the body’s manufacture of glucosamine may be the primary cause of osteoarthritis.

Grape Seed Extract (OPC’s) is an antioxidant that exhibits 50 times more antioxidant power than vitamin E and 20 times more than vitamin C.

Grape Seed Extract (OPC’s) binds to collagen and helps increase elasticity of skin, muscles, tendons and ligaments. Grape seed extract (OPC’s) has been proven by over 25 years of clinical studies to be useful for stroke prevention (grape seed extract helps keep blood viscosity normal), skin rejuvenation and/or wrinkle prevention (strengthens collagen), arthritis and musculoskeletal complaints (antioxidant and strengthens collagen), blood clot prevention (improves blood viscosity), respiratory allergies (antihistamine), food allergies (antihistamine), asthma (antihistamine), ADHD (many cases are allergy-related), longevity and rejuvenation programs (blood viscosity and collagen-strengthening effects).

MSM (Methylsulfonylmethane)is a source of biologically active sulfur. Sulfur is a mineral that is plentiful in the human body and is found in particularly high concentrations in structural tissues (joints, skin, hair, nails). Unfortunately, sulfur is easily destroyed by cooking. This means that many people have a deficiency of this important joint and skin nutrient.

StrontiumThe “forgotten mineral” that not only prevents, but reverses, osteoporosis. If you are concerned about bone density, this is one mineral you should definitely supplement. Since it competes with calcium and magnesium for absorption, strontium should be taken separately from other bone-building formulas.

TurmericThis bright yellow spice herb is also one of nature’s most potent anti-inflammatory substances. Turmeric (and it’s active ingredient, curcumin), help reduce the pain and swelling of joint inflammation. Turmeric also helps the joints through it’s potent  antioxidant properties.

Other Joint and Bone-Healthy Supplements. Fish and flax oil, Mega Soy, Feverfew, Ginger.

Brain and Memory

Keep a Life-Long Healthy Brain and Memory

There are multiple factors that influence brain and memory health. Simple nutritional deficiencies, heavy metal toxicity, chronic inflammation, vascular disease and even stress are risk factors for memory changes and brain diseases.

Taking steps to prevent or slow memory loss is an important consideration for those people who are using anti-aging and longevity measures. Simple lifestyle, dietary and supplement measures can help ensure clear-thinking and good memory well into old age.

Top Brain and Memory Supplements and Herbs

Brain and Memory Therapies
Table of Contents

Brain and Memory
Health Concerns by Topic

Multiple Vitamin/Mineral Formula Alzheimer’s Disease Acetyl-L-Carnitine Anxiety CoQ10 ADD/ADHD DHEA Dementia (senility) DMAE Depression Essential Fatty Acids (EFA’s) Hypothyroid (Low Thyroid) Gastric Acid Self-Test Memory Loss Ginkgo Neurological Disease (ALS,MS) Ginseng (Panax) Parkinson’s Disease Huperizine Stress Melatonin Male hormones Female hormones Thyroid Vinpocetin

Multiple Vitamin/Mineral Formula. The Standard American Diet (S.A.D.) is typically deficient in essential vitamins, minerals and trace minerals. To compound this problem, older people are at even greater risk for nutrient deficiency because they tend to eat less, although their requirements for certain vitamins, such as B6, actually rise with age. Older people often also have problems with efficient absorption of nutrients from food because of low gastric acid function. Even healthy older people often have deficiencies of vitamin B6, vitamin B12, and folic acid, 3 “B complex” vitamins essential for brain and memory health.

Vitamins and certain minerals are involved in biochemical processes throughout the body and are necessary for protecting cognitive function. The B vitamins are especially important for normal brains and nervous system function and help the brain manufacture chemicals (neurotransmitters) that affect mood.

Filling in the “gaps” in diet with an optimal vitamin/mineral formula such as Maxi Multi is one of the most important steps you can take toward preserving good brain health and sharp memory.

Acetyl-L-Carnitine (ALC), a derivative of the amino acid L-carnitine, is a vitamin-like compound that transports fatty acids (“fuel”) into cells. It has been approved in Europe as a “drug” to treat heart and neurological disease. It also acts as a powerful antioxidant in the brain. The acetyl form of L-carnitine (ALC) was found to be substantially more active than L-carnitine in brain cells.

CoQ10 is a naturally-occurring antioxidant produced in the human body. It is vitally involved in energy production. CoQ10 functions as an “energizer” to mitochondria, the body’s energy producing units. Mitochondria, which produce about 95% of the body’s energy, require CoQ10 to “spark” their production of energy units (ATP). Muscles, and the heart in particular, have high requirements for CoQ10.

CoQ10 is essential to the functioning of the mitochondria and many age-related diseases have been linked to lower mitochondrial function. Since CoQ10 production typically declines by about 50% with age, most longevity specialists consider it one of the most important anti-aging nutrients to supplement.

DHEAis a steroid hormone secreted by the adrenal glands. It is a precursor (“master hormone”) for many other steroid hormones including male and female sex hormones (estrogen and testosterone) and corticosteroids. DHEA levels often decline dramatically with age.

Low DHEA levels in the brain and blood are thought to contribute to many of the problems associated with aging including age-related memory and mental decline, decreased strength and muscle mass, lowered immune system response, heart disease and atherosclerosis, and age-related weight gain.

DMAE (dimethylaminoethanol), found in highest concentrations in anchovies and sardines, is also produced in small amounts in the human brain. DMAE is a precursor to the neurotransmitters choline and acetylcholine, although DMAE crosses the blood-brain barrier faster than choline. Once inside brain cells, DMAE is converted to phosphatidylcholine, a substance used for maintenance and repair of cells, especially brain cells. Studies have shown DMAE to be useful for improved memory and short-term concentration and in
Alzheimer’s dementia.

Essential Fatty Acids(EFA’s). Omega-3 fatty acids, especially docosahexaenoic acid (DHA), has attracted significant attention for its ability to boost brain function. DHA is found in very high concentrations in cell membranes and is required by developing infant brains. Studies have shown that DHA helps protect brain cells by suppressing a neurotoxic substance called amyloid-beta (beta amyloid is a substance found in the brains of Alzheimer’s patients).

Ginkgo is one of the most well-studied herbs for age-related memory changes. It is also a potent antioxidant. Ginkgo increases circulation to small-diameter blood vessels (such as those in the brain and extremities) and inhibits platelet aggregation (decreases blood “stickiness”). Ginkgo also has anti-allergy effects. Ginkgo is one of the best-selling natural remedies worldwide. Many alternative physicians and researchers feel that ginkgo should be part of the Longevity Protocol for everyone over age 50.

Ginseng(Panax spp.) Panax ginseng was considered the “Herb of Emperors” in ancient China, and only the emperor was allowed to use ginseng. This was because the potent effects of ginseng were felt to be “too precious” for the common man.

Modern research has confirmed ginseng’s amazing powers. Ginseng improves immunity through a wide variety of mechanisms. It stimulates DNA synthesis and is useful for anti-aging and chronic disease. Studies have shown that ginseng improves both physical and mental stamina. “It’s not just for the emperor any more!”

Huperizine or Chinese Club moss, contains a substance (Huperizine A) which prevents the breakdown of acetylcholine in the brain. Acetylcholine is a neurotransmitter necessary for memory function. The most promising drugs for Alzheimer’s disease work in the same manner, although Huperizine appears to have a more precise mechanism whereby it protects acetylcholine. Huperizine may be useful for both Alzheimer’s and non-Alzheimer’s memory loss.

Melatonin, a hormone manufactured by the pineal gland, is best-known as an aid for insomnia. Beyond it’s use as a sleep aid, melatonin is also a powerful antioxidant that crosses the blood/brain barrier and helps protect the central nervous system against injury, disease, and aging. Melatonin levels decrease with age, and this reduction in melatonin levels results in many age-related concerns and complaints: sleep difficulties, an increased susceptibility to stress-related diseases, reduced immunity, and increased susceptibility to damage and disease caused by free radicals. Many researchers consider melatonin to be one of the most powerful anti-aging substances available.

Natural Hormone Replacement Therapy (estrogen, progesterone, testosterone, pregnenelone) Both women and men appear to benefit from natural hormone replacement therapy after age 40. By “natural,” I mean using hormones that are identical to what the body manufactures and in amounts that a healthy body produces in early adulthood. This is a very different type of hormone replacement from the semi-synthetic forms and doses used in conventional medicine.

Male hormones: testing and replacement

Female hormones: testing and replacement

Thyroid. Low thyroid function impairs memory and thinking. A test should be performed to determine thyroid function and natural supplements or thyroid replacement therapy should be started if thyroid levels are low.

Vinpocetin is derived from the periwinkle plant. More than 100 studies have shown that vinpocetin increases cerebral circulation (blood supply to the brain) AND improves brain energy production (ATP) and oxygen use. The potential benefits of vinpocetin include treatment of stroke, inner ear problems that result in dizziness, hearing loss, vision loss, neurological disorders, memory loss.

BENIGN PROSTATE ENLARGEMENT (BPH)

Natural Support For This Common Condition Of Older Men

An estimated 60% of men over age 40 have an enlarged prostate gland. Enlargement of the prostate gland causes obstruction of urine outflow. Symptoms include increased urinary frequency, nighttime urination, a sense of urgency, and reduced force of urine stream. At its most severe stage, an enlarged prostate gland can completely block the outflow of urine, resulting in urine retention in the blood.

The primary cause of an enlarged prostate is due to conversion of testosterone into dihydrotestosterone (DHT). Dihydrotestosterone is a hormone that stimulates the growth of prostate gland cells. High levels of DHT are associated with prostate gland enlargement, prostate gland cancer, and male pattern baldness. Excess estrogens in males can also aggravate the condition, as can elevated cholesterol levels.

Males 50 and over should have a PSA blood test performed annually. Normal levels are from 0-4. Numbers above this level suggest benign prostate enlargement or prostate cancer.

DIET AND LIFESTYLE RECOMMENDATIONS

  • Decrease consumption of carbohydrates and increase intake of protein. Soy and pumpkin seeds are especially beneficial.
  • Regular exercise improves circulation to the prostate gland AND helps normalize hormone levels.
  • Decrease or eliminate consumption of alcohol, caffeine, and sugar.
  • Maintain a normal weight. Overweight males have a two—fold increase in BPH.
  • Use soy foods 3 or more times per week. Soy is associated with decreased growth of prostate cells and also helps normalize cholesterol levels. (Soy protein powder or soy capsules can be used to supplement soy intake)
  • Don’t smoke. Cigarette smoke contains cadmium, which increases the enzyme that converts testosterone to DHT.

PRIMARY SUPPORT

  • Maxi Multi: 3 caps, 3 times per day with meals. Optimal (not minimal) doses of zinc are especially important.
  • Flax seed: 1 TBS. per day ground seed OR Flax seed oil: 2 caps, 3 times per day with meals.
  • Saw Palmetto: (160mg) 1-2 caps, 2 times per day. (Target dose: 160-320 mg per day).

TESTS:

DR. MYATT’S COMMENT:

Other herbs, such as pygeum and nettles, are also beneficial for prostate enlargement, but Saw Palmettohas by far the most research behind it. In clinical studies, Saw Palmetto has worked as well as the drug Proscar (finasteride) with no negative side effects. Always have a male hormone profile performed.

Beta Carotene

A Fat-soluble Antioxidant Vitamin

Carotenes are plant pigments with vitamin A and antioxidant activity. They perform many functions, including maintenance of eye health, cancer and cardiovascular disease prevention, immune-system enhancement and skin/epithelial health.

Dr. Myatt’s comment: Use only natural beta carotene. Synthetic carotenes have been shown to have negative health effects. Our Wellness Club beta carotene is from D. salina and contains 100% natural mixed carotenoids. [Henkel brand Betatene®, the best available].

Bio Pro (Thymic Protein A)

Increase Stamina and Boost Immunity

Bio Pro Thymic Protein AThe thymus gland is a small lymphoid organ located behind the sternum and between the lungs. It is the “bootcamp” where young immune cells, the “T cells,” go to mature. The thymus gland also produces peptide hormones that keep these same T cells active once they leave the thymus and begin their function as immune cells in the body. Damage to the thymus glad results in lowered immunity. The thymus gland tends to shrink with age, which may contribute to the decrease of immune response seen in aging.

T cells are that part of the immune system that helps protect us from fungus, viruses and cancer. Their role in cancer prevention is especially important. Mature T cells do not function correctly unless programmed by thymic hormones.

Studies have shown that many cancer patients live longer (often double their expectancy) when thymic hormones are used as an adjunct to conventional treatment. Researchers surmise that this is due to the immune-protecting effects of thymus hormones which help offset the immune-suppressing effects of most chemotherapy and radiation.

Thymic Protein A is a highly purified mix of bovine thymus hormones that is useful for a variety of immunocompromised conditions including:

  • early stage AIDS
  • hepatitis
  • autoimmune conditions
  • cancer
  • allergies
  • chronic infections
  • candidiasis
  • asthma
  • anti-aging protocols

Because the thymus gland tends to shrink with age, and because this shrinkage is associated with decreased immunity, many longevity specialists recommend thymus hormone supplementation as part of an anti-aging program.

Recommended dose: 2-4mcg per day.

Each (one) packet contains: 4mcg thymic protein with intact hormones. 30 packets per box.

Click here to
Order This Concierge Product Wellevate

This is a separate website and you will need to create a new account to order.

Black Cohosh Plus+

Menstrual and Menopausal Symptom Relief

Black Cohosh Plus+Black cohosh (Cimicifuga racemosa) has long been used in traditional medicine for relief of menstrual cramps and hot flashes. Western medical studies have confirmed Black cohosh’s estrogenic effects.

Dong Quai (Angelica sinensis) has known estrogenic effects coupled with the ability to stabilize blood vessels. This “stabilization” is believed to be partly responsible for menopausal hot flash relief.

Chasteberry (Vitex angus-castus) helps normalize sex hormone levels by acting on the pituitary gland and hypothalamus.

Black Cohosh Plus+ is a special formula of these three herbs designed especially for women experiencing the symptoms of menopause or menstrual cramping.

Each (1) Capsule contains:

  • Black Cohosh extract (Cimicifuga racemosa) 40 mg, standardized to 2.5% [1 mg] triterpene glycosides,
  • Chasteberry fruit powder (Vitex agnus-castus) 100 mg,
  • Dong Quai root (angelica sinensis) 100 mg.

Suggested dose 1-2 Capsules, 2 times per day with meals. Begin with 2 caps per day. If significant improvement in symptoms is not seen in 3 weeks, increase dose to 4 caps per day. This formula is safe to take indefinitely for menopausal symptoms.