Turmeric:


Powerful Cancer-fighting Herb
that drug companies are rushing to imitate.

An ever-growing body of scientific evidence demonstrates that turmeric — the bright yellow spice herb used in East Indian cooking — has potent anti-cancer properties. According to Bharat Aggarwal, chief of cytokine research at the University of Texas M.D. Anderson Cancer Center, the research to date shows that turmeric’s anti-cancer “promise is enormous.” This evidence and opinion was reported at the recent Society for Integrative Oncology conference and is also posted on the American Cancer Society’s website (www.cancer.org).

Turmeric, and it’s primary active ingredient curcumin, is the main ingredient in curry and a member of the ginger family. In addition to it’s anti-cancer properties, turmeric is a potent antioxidant, anti-inflammatory and liver-protecting herb. Expect to see and read a lot more about this herb in the future, although Wellness Club members have known about the benefits of turmeric for over a decade!

You can learn more about turmeric and find one of the most potent turmeric supplements available on The Wellness Club website by visiting Turmeric: Antioxidant, Anti-inflammatory and Anti-Cancer Herb.

References

1.) Curcumin inhibits the mammalian target of rapamycin-mediated signaling pathways in cancer cells. Beevers,Li,Liu,Huang. Int J Cancer. 2006 Mar 20
2.) Antitumor action of curcumin in human papillomavirus associated cells involves downregulation of viral oncogenes, prevention of NFkB and AP-1 translocation, and modulation of apoptosis. Divya CS, Pillai MR. Mol Carcinog. 2006 May;45(5):320-32.
3.) Curcumin mediates ceramide generation via the de novo pathway in colon cancer cells. Moussavi M, Assi K, Gomez-Munoz A, Salh B. Carcinogenesis. 2006 Feb 25; [Epub ahead of print]
4.) Overexpression of p65/RelA potentiates curcumin-induced apoptosis in HCT116 human colon cancer cells. Collett GP, Campbell FC. Carcinogenesis. 2006 Feb 23; [Epub ahead of print]
5.) Induction of G2/M arrest and inhibition of cyclooxygenase-2 activity by curcumin in human bladder cancer T24 cells. Park C, Kim GY, Kim GD, Choi BT, Park YM, Choi YH. Oncol Rep. 2006 May;15(5):1225-31.
6.) Molecular targets of dietary agents for prevention and therapy of cancer. Aggarwal BB, Shishodia S. Biochem Pharmacol. 2006 Feb 23; [Epub ahead of print]
7.) Inhibition of telomerase activity and induction of apoptosis by curcumin in K-562 cells. Chakraborty S, Ghosh U, Bhattacharyya NP, Bhattacharya RK, Roy M. Mutat Res. 2006 Jan 27; [Epub ahead of print]
8.) Curcumin differentially sensitizes malignant glioma cells to TRAIL/Apo2L-mediated apoptosis through activation of procaspases and release of cytochrome c from mitochondria. Gao X, Deeb D, Jiang H, Liu YB, Dulchavsky SA, Gautam SC. J Exp Ther Oncol. 2005;5(1):39-48.
9.) Multiple biological activities of curcumin: a short review. Maheshwari RK, Singh AK, Gaddipati J, Srimal RC. Life Sci. 2006 Mar 27;78(18):2081-7. Epub 2006 Jan 18.
10.) Curcumin, an atoxic antioxidant and natural NFkappaB, cyclooxygenase-2, lipooxygenase, and inducible nitric oxide synthase inhibitor: a shield against acute and chronic diseases. Bengmark S. JPEN J Parenter Enteral Nutr. 2006 Jan-Feb;30(1):45-51.
11.) Antiproliferation and apoptosis induced by curcumin in human ovarian cancer cells. Shi M, Cai Q, Yao L, Mao Y, Ming Y, Ouyang G. Cell Biol Int. 2006 Mar;30(3):221-6. Epub 2005 Dec 22.
12.) Synergistic inhibitory effects of curcumin and 5-fluorouracil on the growth of the human colon cancer cell line HT-29. Du B, Jiang L, Xia Q, Zhong L. Chemotherapy. 2006;52(1):23-8. Epub 2005 Dec 9.
13.) Curcumin induces human HT-29 colon adenocarcinoma cell apoptosis by activating p53 and regulating apoptosis-related protein expression. Song G, Mao YB, Cai QF, Yao LM, Ouyang GL, Bao SD. Braz J Med Biol Res. 2005 Dec;38(12):1791-8. Epub 2005 Nov 9.
14.) Inhibition of cellular proliferation and induction of apoptosis by curcumin in human malignant astrocytoma cell lines. Nagai S, Kurimoto M, Washiyama K, Hirashima Y, Kumanishi T, Endo S. J Neurooncol. 2005 Sep;74(2):105-11.
15.) Curcumin inhibits human colon cancer cell growth by suppressing gene expression of epidermal growth factor receptor through reducing the activity of the transcription factor Egr-1. Chen A, Xu J, Johnson AC. Oncogene. 2006 Jan 12;25(2):278-87.

 

 

Urinary Tract Health


Your Guide to a Healthy “Water Works”

The urinary tract — including the kidneys, bladder and urethra — don’t get as much “press” as other bodily systems. Since the urinary tract is responsible for much of the body’s waste removal, in addition to the role it plays in blood pressure regulation, keeping a healthy urinary tract is important for good health.

Many drugs cause damage to the kidneys, even those used to treat kidney infections! For this reason, I always prefer to use natural remedies as a first line of defense in keeping the urinary tract healthy.

Urinary Tract
 Nutrients and Herbs
Urinary-Tract
Health Concerns

B.A.M.
Bromelain
Cranberry
Echinacea/Goldenseal
Vitamin C Bladder Infection (Cystitis)
Kidney Stones
Prostate Enlargement

Urinary Tract Infection

 

Urinary Tract Infections (UTI’s)


Natural Ways to Overcome UTI’s

Urinary tract infections (UTI) are a common and uncomfortable condition that affects some 50 percent of all women and girls (and a lesser number of men and boys) over the course of a lifetime. UTIs account for 10 million doctor visits annually. Some people appear to be more susceptible than others. For example, women who experience one UTI are more likely to have recurrences from time to time.

Urinary tract infections can range from annoying to life-threatening. When confined to the bladder, most UTI’s are merely uncomfortable but can sometimes be downright painful. If bacteria ascends to the kidneys, serious kidney damage and even kidney failure can result.

Urinary Tract Terminology

When an infection involves only the urethra, the condition is called “urethritis.” When the bladder is involved, the condition is called “cystitis.” When the infection back all the way up to the kidneys, it is called “nephritis” or “pyelonephritis.”

Causes of UTI’s

Ninety percent (90%) of all UTI’s are caused by E. coli bacteria. E. coli is the most common “friendly” bacteria in the colon (large intestine). As long as it stays in the gut, things are fine. When e.coli bacteria make their way into the urinary tract, they can cause an infection. The remaining 10% of UTI’s are caused by other types of microbes including Chlamydia, Mycoplasma, Neisseria gonorrhoreae, and others. These type of “bugs” are typically spread by sexual contact and can cause the more serious types of infection.

Most bacteria that find a way into the urinary tract (as can occur during sexual intercourse) are simply washed out with the urine. E. coli can “grab” onto cells that line the urinary track by binding to a sugar-like molecule found on normal urinary tract cells.

Conventional Medical Treatment of UTI’s

Conventional medicine uses antibiotics to treat UTI’s, period. Antibiotics can be highly effective at knocking down a UTI, but there are numerous drawbacks.

Antibiotics not only kill bacteria in the urinary tract, but they can kill a lot of “friendly bacteria” in the gut as well. Destruction of protective GI bacteria can lead to yeast infections or worse, can allow “unfriendly” strains of bacteria to colonize the gut.

Disturbing the normal gut flora often leads to a secondary vaginal yeast infection. Many women who take antibiotics for UTI simply come to expect that they will have a vaginal yeast infection (requiring a second medication of an anti-fungal) for treatment.

Bacteria can become resistant to antibiotics. Not only can the antibiotic stop working (or become less effective) for treating the UTI, but antibiotics can become less effective for treating infections elsewhere in the body. Remember, overuse of antibiotics is the most common cause of “Super Bugs”— bacteria that do not respond to any known antibiotic.

Antibiotics can sometimes cause life-threatening allergic reactions. Other reactions to antibiotics include diarrhea or constipation, nausea, and sometimes vomiting. An estimated 25% of people who receive an antibiotic will develop a secondary gut infection of an organism called C. difficile.

Alternative Treatments for UTI

Most cases of UTI can be successfully treated without antibiotics. Because of the many drawbacks of antibiotics, I always prefer to try natural options first. Results are usually seen within 24 hours, so it is easy to tell if the natural treatment is working.

D-mannose is a sugar molecule and close cousin of glucose. Many alternative physicians have found that it can cure 90 percent of all UTIs within 1 to 2 days. Because D-mannose works by preventing bacteria from sticking to the lining of the urinary tract and not by direct antibiotic action, it does not have any of the potential for negative side-effects like antibiotics so.

D-mannose tastes good (because it is related to the sugar molecule, although it does not raise blood sugar levels). It is so safe that it can be used by pregnant women and young children. It is also one of the few “medicines” that children actually enjoy taking!

Although D-mannose is virtually unknown to conventional medical doctors, many research reports have proven its mode of action and effectiveness against E. coli, the microorganism that causes 90% of all UTIs. Moreover, nearly 15 years of clinical experience has also shown that it is just almost as effective at curing UTIs as antibiotic drugs but without any of the negative side-effects.

Vision Health


Maintain Good Eyesight Life-Long

Eye ChartDeclining vision is not a “requirement” of advancing years. It is possible to maintain good vision life-long by following a few simple health measures.

The eye requires a number of nutrients — vitamins, minerals and accessory nutrients — to remain healthy. Many of these nutrients are deficient in the Standard American Diet (S.A.D.). An optimum potency (not minimum potency) daily vitamin and mineral supplement such as Maxi Multi goes a long way toward preserving good vision. Nutrients contained in Maxi Multi that are particularly important for eye health include: beta carotene (natural source), carotenoids, vitamins A, E, C, B2, B3, selenium and zinc.

Lack of normal stomach acid (low gastric acid) and resultant failure to absorb nutrients from diet and supplementation can contribute to eye disease. I recommend a Gastric Acid Self-Test for anyone concerned about vision and eye health.

Visit this page for General Eye Health Recommendations.

Vision Health Supplements
Vision-Related
Health Concerns
Acetyl-L-Carnitine
Beta Carotene
Bilberry Plus+
CoEnzyme Q10 (CoQ10)
Eye Drops from Hell
Fish Oil
Ginkgo
Grape Seed Extract
Lutein Plus+
Lycopene
Maxi Greens
Maxi Multi
Melatonin
Vitamin C Cataracts
Glaucoma
Macular Degeneration

 

 

 

 

Prostate Cancer


:

Lecture Notes By Dr. Myatt

The text that follows is a transcript of the lecture notes for a lecture presented by Dr. Myatt in May of 2000 at the 2000 Pacific Northwest Herbal Symposium where Dr. Myatt was a featured lecturer speaking on several subjects. It is reproduced here in it’s entirety including annotations and references (as is expected of any lecture presented to a medical or scientific body) so that readers may verify the information for themselves and engage in further research. We hope that this will be information useful to persons with an interest in this disease.

Botanical and Nutritional Considerations in the Treatment of

Dana Myatt, N.M.D.

Abstract

Prostate carcinoma is a hormone-dependent cancer. Therefore, in addition to general immune enhancing and anti-cancer therapies, hormonal manipulation has a role to play in treatment of this disease.

Overview

Prostate carcinoma is the most common male cancer in the U.S. It accounts for an estimated 32% of all newly diagnosed cancers. (Other forms of prostate cancer, such as sarcoma, are rare and are not hormone-dependent). The incidence of disease increases with each decade of life over age 50. (1) Prostate cancer rates have risen 108% since 1950, believed due in part to earlier detection. Death rates from this disease have increased 23%. 
There is great debate in the medical community regarding the value of conventional treatment. Prostate cancer is, in most cases, slow-growing. Increased survival rates reported in some studies may be due to earlier detection, not treatment. Many newly diagnosed and early stage cancers in older men would never progress to morbidity or mortality. Considering the risk of impotence (50-60% with surgery), incontinence (from surgery or radiation) and other treatment side-effects, the value of conventional therapy must be questioned in all cases of cancer in older men.

Botanical and nutritional treatment for cancer can be considered an adjuvant therapy in all cases of prostate carcinoma and the sole therapy in many. Even when conventional treatment is deemed advisable, non-traditional uses of conventional drugs may be safer and more advantageous than standard therapy. This is because, in it’s early stages, prostate cancer is highly controllable with hormone-blocking therapy.

Laboratory Evaluation of

In additional to generalized immune testing and basic cancer workup (chemistry screen, CBC, TFT’s, etc.), several tests specific to prostate disease allow the clinician to track progression non-invasively and with greater accuracy. These tests include prostatic-specific antigen (PSA), free PSA, prostatic acid phosphatase (PAP), and prolactin. 

PSA is now used as the preferred screening test for both benign prostatic hypertrophy (BPH) and prostate cancer. Because PSA may be elevated in both benign and cancerous prostate disease, the test is not specific for prostate cancer. Values in the “indeterminate” range (4-12) present a special diagnostic dilemma. It is further estimated that 25% of men with prostate cancer will have PSA’s less than 4. Taken together, the PSA test poses a significant number of both false-negative and false-positive results. The PSA is an accurate measure of cancer cell activity once the diagnosis has been established.

Free-PSA is a more recent marker that has not yet been universally embraced by conventional medicine. Current research suggests that the free-PSA is a useful “next step” for evaluating elevated PSA’s. In men with PSA’s ranging from 4.1-10, higher levels of free-PSA (18.9 median value) correlated with benign disease while lower levels of free-PSA (10.1 median) correlated with cancer. It is estimated that 95% of “indeterminate” PSA readings could be clarified non-invasively with the additional use of the free-PSA test. (3)

Prostatic acid phosphatase (PAP) was the prostate cancer screening test that preceded use of the PSA. An elevated PAP in a patient with known prostate cancer is indicative of lymphatic spread of the disease. (4)

Prolactin hormone is an additional growth factor to the prostate gland, and rising prolactin levels correlate with progression in advanced prostate cancer cases. Prolactin receptors are found on prostate cancer cells, and it is postulated that these receptors may facilitate the entry of testosterone into the cell. Even with hormone ablation therapy, detectable androgen remains in the blood from adrenal sources. Blocking prolactin secretion may there fore be another method for slowing progression of the disease. It is recommended that prolactin levels be kept below 3 in all patients with hormone-responsive cancers. (5)

Specific Goals of Therapy

Testosterone, prolactin, cortisol, insulin, and arachidonic acid-derived prostaglandins (especially PGE2) act as growth factors for prostate cancer. Cyclooxygenase is the enzyme that catalyzes the conversion of arachidonic acid to prostaglandins. Decreasing circulating levels of these hormones and blocking inflammatory pathways should be undertaken in addition to non-specific cancer therapies such as immune enhancement.

References

1.) Beers, Mark M.D., Berkow, Robert M.D. , editors, The Merck Manual of Diagnosis and Therapy, Merck research Laboratories, 1999, p. 1918.
2.) Boik, John, Cancer and Natural Medicine, Oregon Medical Press, 1996, p. 87
3.) Faloon, William, Disease Prevention and Treatment Protocols, Life Extension foundation, Hollywood, FL, 1998, p. 192.
4.) Murphy, Gerald M.D., Lawrence, Walter Jr. M.D., Lenhard, Raymond M.D., Clinical Oncology, American Cancer Society, Atlanta, 1995, p. 315. [copies of this textbook may be obtained by calling your local branch of the American Cancer Society or call 1-800-ACS-2345].
5.) European Journal of Cancer, Vol 31A, No. 6, 1995.

Materia Medica classified by action

Reduce sex hormone bioavailability

Glycine max -soy
Linum ussatatissimum -flax
Arctium lappa -burdock
low dietary saturated fat
high dietary fiber

Decrease testosterone

Cannabis sativa- marijuana
Serenoa Spp.- Saw palmetto
Vitex spp
Rx: Casodex, flutamide, Lupron, Zoladex

Decrease prolactin

Vitex spp.
vegetarian diet
Rx: Bromocriptine, Pergolide, Dostinex

Botanical Materia Medica

Arctium lappa (Compositae)- Burdock

Burdock reduces sex hormone bioavailability, perhaps due to its lignan content.(1) In vitro, it induces differentiation and inhibits tumor cell proliferation. (2) Burdock is considered highly in both Western and Chinese medicine as a detoxifier and it is an ingredient in the Hoxey formula. it is thought to stimulate the removal of excess metabolic acids. (3)

Linum ussitatissimum (Linacea)- Linseed, flax seed

Flax seed is much higher in lignans than other plants. Lignans inhibit sex hormone availability. Antiinflammatory effects are attributed to the high omega-3 fatty acid content of the seed oil.

Glycine max (Leguminosae)-Soy

Soy beans contain protease inhibitors, fixed oils, coumestrol, isoflavones including daidzein and genistein, lecithin, protein, vitamins and minerals. Soy foods reduce hormone bioavailability and cholesterol levels through several possible mechanisms, including weak estrogenic effects of the phytoestrogenic isoflavones and fiber content. Genistein is cytotoxic, induces apoptosis and differentiation, inhibits angiogenesis and metastasis (4), and blocks protein kinase which is a cancer growth factor (11) . The isoflavones in soy are both antioxidant and antimutagenic.(5)

One study of 8,000 Japanese living in Hawaii found that men who had the highest intake of soy had the lowest incidence of prostate cancer. Soy-eaters diagnosed with prostate cancer nevertheless have the lowest death rate in the world from the disease.(6)

Cannabis sativa (Cannabinaceae)- Marijuana

Marijuana contains flavonoids, volatile oils, alkaloids and over 60 different cannabinoids including THC.(7) Smoking the herb reduced testosterone levels or inhibited testosterone receptors in both animals and humans. It is known that marijuana smoking decreases male fertility. (8,9,10)

Serenoa repens, S. serrulata (Palmaceae)- Saw palmetto

Saw palmetto blocks the conversion of testosterone to dihydrotestosterone (DHT) (11) and there is evidence that DHT may be five times as potent as testosterone in stimulating prostate cancer cell growth. (12)

Vitex agnus-castus, V. negundo (Verbenaceae)- Chaste berry

Vitex spp. decreases testosterone production in vivo (13) and inhibits prolactin synthesis and release in animal models (14). As the name “chaste tree” implies, this herb was traditionally used by monks to reduce libido.

PC-SPEC

PC-SPEC is a new and novel Chinese herb formula used in the treatment of prostate cancer. “Spec” is Latin for hope, and the formula is reported to be effective in extending quality and length of life even in advanced, hormone-refractory cancers. The formula is cytostatic and cytotoxic, and regulates apoptosis (1). It may stimulate T4 (helper) cells and macrophages (2) and lower PSA levels (3). The popularity of the formula was enhanced by a recent mention in the New England Journal of Medicine which reported that:

“We found PC-Spec…. has potent estrogenic activity in yeast, mice, and humans. In patients with prostate cancer, it causes clinically significant reductions in serum testosterone concentrations, decreases PSA, and with side effects similar to those of pharmacologic doses of estrogen….. PC-SPEC may prove useful in the treatment of hormonally sensitive prostate cancer…..”(3).

The formula contains herbs which may address prostate cancer on a number of levels. According to the book New Guidelines for Surviving (4), the herbs and actions of PC-SPEC include:

1.) Isatis indigotica (da qing ye) contains beta sitosterol, a phytosterol which lowers the bioavailability of estrogen and reduces tumor yield in animals.
2.) Glycyrrhiza spp. (gan cao) stimulates the immune system and possesses in vitro antitumor activity. It also helps lower testosterone levels.
3.) Panax pseudo-ginseng (san qi) stimulates NK cell activity.
4.) Ganoderma lucidum (ling zi) contain polysaccharides that inhibit cancer cells and extend the lifespan of test animal with lung cancer up to 195%.
5.) Scutellaria baicalensis (huang qin) promotes apoptosis, stimulates the immune system and inhibits tumor-cell proliferation.
6.) Dendranthema morifolium Tzvel (Chu-hua) is a lesser-known Chinese herb with reported antiviral and detoxifying properties.
7.) Rabdosia rubescens (don ling cau) is a pain-relieving herb with multiple antitumor effects. Increased survival rates have been noted in patients with esophageal cancer.
8.) Serenoa repens or S. serrulata (Saw palmetto) decreases the bioavailability of testosterone and is widely used in the treatment of BPH.

The recommended dose is 6-12 capsules per day depending on the stage of the disease. This puts the cost of the formula at $300-$600 per month. (CHT averages $800 per month to give some perspective). Since the formula is a non-FDA approved herbal combination, it is available without a prescription.

Dr. Myatt’s comment: This formula has gotten a lot of good press lately. I’d like to see if the results will meet the hype. Unfortunately, since the formula is a non-FDA approved herbal remedy, I have found it challenging to get patients to take it with consistency in the doses recommended. I have yet to see results in two patients who have used it with regularity. PC-SPEC may indeed represent a breakthrough in the treatment of cancer. It could also be that some herbal product manufacturers are getting as clever as the drug companies in creating “buzz,” and getting journal space, about new products. How many “breakthrough” drugs have come and gone? Let’s hope PC-SPEC fares better than the current conventional treatments for prostate cancer.

References

1.) Halicka HD et al.: Apoptosis and cell cycle effects induced by extracts of the Chinese herbal preparation PC-SPEC. Intl J Oncology, 1997;11:437-448.
2.) Whittaker J: The Art of Alternative Medicine. ACAM Conference Proceedings Notes, Nov. 1998.
3.) DiPaola RS et al.: Clinical and biologic activity of an estrogenic herbal combination (PC-SPEC) in prostate cancer. New Engl J Med, Sept. 17, 1998;339(12);785-791.
4.) Lewis, James Jr.: New Guidelines for Surviving , Westbury, NY: Health Education Library Publisher, 1998.

Nutritional Materia Medica

Vitamin D3 (cholecalciferol)

Vitamin D3 induces prostate cancer cell apoptosis by apparent translocation of the cancer cell androgen receptor. This makes the cell less susceptible to testosterone-induced proliferation (15). D3 induces differentiation, inhibits angiogenesis and shows antitumor activity. It may also upregulate vitamin A receptors. (16)

Because vitamin D has the potential to cause toxicity, doses over 1,000mg should be carefully monitored. Increased blood calcium levels can result from toxicity. In clinical practice, D3 appears to benefit metastatic bone disease in higher doses, perhaps because this vitamin is needed for normal calcification of bone matrix.

Food sources of vitamin D include cold water fish (salmon, mackerel, herring), butter, egg yolks and dark green leafy vegetables. Sunlight acting on the skin will also create vitamin D. In areas of decrease sunlight, increases of breast and colon cancer have been observed. (17)

Melatonin

Melatonin is a hormone produced by the pituitary gland. It regulates circadian rhythms and plays a role in sleep regulation. It is also a more potent antioxidant than glutathione or vitamin E (19). In vitro, melatonin demonstrates antiestrogen activity and immune stimulation (18). Recent research shows that melatonin inhibits cell proliferation profoundly in vivo but only weakly in vitro. It is synergistic with IL-2 and increases the effectiveness of IL-2 treatment. (20)
 

CoQ10 (ubiquinone)

CoQ10 is a vitamin-like substance that is involved in mitochondrial energy production. The heart is a high user of CoQ10, and many chemotherapeutic drugs deplete body stores of this nutrient. CoQ10 has been used successfully to reduce chemotherapy-induced cardiotoxicity.
In breast cancer patients, a dose of 90mg daily increase late-stage survival dramatically. Three cases of complete remission have been documented at higher doses (300-400mg) per day. (21)

Enzymes (multi enzymes)

Digestive enzymes, whether from animal sources (pancreatin, etc.) or botanical (bromelain, papain), have been shown to increase survival time, inhibit metastasis, and stimulate immune cells. Enzymes induce differentiation and inhibit angiogenesis (22), possibly through antifibrinolytic mechanisms. It has also been postulated that enzymes may help unmask tumor cells and make them more accessible to the immune system.

Dietary Guidelines

Low saturated fat diets decrease the body’s endogenous and exogenous hormone production. Conversely, diets high in saturated fats decrease NK cell activity and increase arachidonic acid, an inflammatory precursor. Rates of breast, colon, prostate, uterine, ovarian and testicular cancers are significantly higher in countries with high saturated fat intakes.

Saturated fats promote inflammatory prostaglandin synthesis while omega-3 fatty acids are antiinflammatory.

Low carbohydrate diets decrease the availability of glucose and insulin. Insulin is a growth factor for cancer and the primary metabolic pathway of cancer cells is anaerobic glycolysis, meaning that cancer cells thrive with a high glucose environment. In animal studies, even slight change toward metabolic acidosis resulted in tumor regression. A low carbohydrate diet which induces ketosis (metabolic acidosis) may duplicate this effect. Overweight patients can afford to lose weight on such a diet, to further reduce their endogenous hormone production. (Fat cells manufacture estrogen).
 

Foods of Special Benefit

garlic
lemon zest (the peel contains limonene)
fish
flax seed
soy and soy products
fresh vegetables (especially non-starchy, dark leafy greens)
olive oil
blueberries and other berries (high in flavonoids and low in sugars)
grains (whole grain only, to reduce insulin response and increase fiber content. Grains should be used sparingly. In patients with more than twenty pounds to lose, gains need not be used at all until desired weight is achieved)

Materia Medica References

1.) Boik, John: Cancer and Natural Medicine, Oregon Medical Press, 1995, p. 159
2.) Ibid., p. 177
3.) Tilgner, Sharol N.D.: Medicines from the Earth, Wise Acres Press, 1999, p. 44.
4.) Ibid, Boik, p. 184.
5.) Editors of time-Life Books: The Drug and Natural Medicine Advisor, time-Life Books, Alexandria, VA. 1997, p.704.
6.) Yeager, Selene, editor: Food Remedies., Prevention Health Books, Rodale Press, 1998, p. 494.
7.) Chevallier, Andrew: Encyclopedia of Medicinal Plants. DK Publishing, London, 1996, p.180.
8.) Barnett G.,Chaing CW, Licko V: Effects of Marijuana on testosterone in male subjects. J Theor Biol 1983 Oct 21; …104(4):685-92
9.) Fujimoto GI, Morrill GA, O’Connell ME, Kostello AB: Effects of cannabinoids given orally and reduced appetite on the male rat reproductive system. Pharmagology 1982;24(5):303-13.
10.) Purohoit V, Ahluwahlia BS, Vigersky RA: Marijuana inhibits dihydrotestosterone binding to the androgen receptor. Endocrinology, 1980 Sep; 107(3):848-50.
11.) Sultan C, Terraza A, Devillier C, Carilla E, et al.: Inhibition of androgen metabolism and binding by a liposteric extract of Serenoa repens B in human forskin fibroblasts. J Steroid Biochem 1984 Jan; 20(1):515-9.
12.) The effects of Flutamide on total DHT and nuclear DHT levles in the human prostate. Prostate, 1981, 2/3: 309-314.
13.) Bhargava SK: Antiandrogenic effects of a flavonoid-rich fraction of Vitex negundo seeds: a histological and biochemical study in dogs. J Ethnopharmacol 1989 Dec; 27(3):327-39.
14.) Bohnert KJ: The use of Vitex agnus castus for Hyperprolactinemia. Quarterly Review of Nat Med Spring 1997;19-20.
15.) Vitamin D and : 1,25 Dihydroxyvitamin D3 receptors and actions in human prostate cancer cell lines. Endocrin 1993;132(5):1952-60.
16.) Majewski S, Szmurlo A, Marczak M, Jablonska S, Bollag W: Inhibition of tumor-cell induced angiogenesis by retinoids, 1,25-dihydroxyvitamin D3 and their combination. Canceer Lett 1993 Nov 30; 75(1):35-9.
17.) Murray M: Encyclopedia of Nutritional Supplements. Prima Publishing, 1996: p.40.
18.) reiter RJ, Melchiorri D, Swewerynek E, Poeggeler B, et al.: A review of the evidence supporting melatonin’s role as an antioxidant. J Pineal Res 1995; 57:125-28.
19.) Hill SM, Spriggs LL, Simon MA: The growth inhibitory action of melatonin on human breast cancer cells is linked to the estrogen response system. Cancer Lett 1992 Jul 10;64(3):249-56.
20.) Lissoni P, Barni S, Cazzaniga M, et al.: Efficacy of the concommitant administration of the pineal hormone melatonin in cancer immunotherpay with low-dose IL-2 in patients with advanced solid tumors who had progressed on IL-2 therpay alone. Oncology 1994b Jul-Aug; 51(4):344-7.
21.) Boik, John: Cancer and Natural Medicine, Oregon Medical Press, 1995, p. 71.
22.) 22.) Ibid., p.184.

 

Psoriasis


Do You Suffer “The Heartbreak Of Psoriasis”?

Once thought to be little more than an annoying and unsightly skin condition, research now shows psoriasis to be a symptom of much more serious problems.

What is Psoriasis?

Psoriasis is an autoimmune disease with abnormally fast production of skin cells (up to 1,000 times normal) accompanied by inflammation.

Rapidly-multiplying skin cells pile up, creating a silvery scale. Skin underneath this scale is typically inflamed, itchy and painful. The condition is not contagious.

Psoriasis, once considered a “skin disease,”  is now recognized as a systemic (body-wide) autoimmune condition highly associated with:

  • Cardiovascular disease, high blood pressure and stroke (1-14)
  • Diabetes and metabolic syndrome (7-15)

Other conditions associated with psoriasis include depression, insomnia/sleep difficulties, COPD, GERD and arthritis.

What Causes Psoriasis?

The precise cause of psoriasis is not known but a number of factors and have been identified:

  • Genetic.  About one-third of people with psoriasis have a family member who also has the disease, suggesting a genetic component in some sufferers.
  • High cGMP to cAMP ratios
  • Excess inflammation
  • High inflammatory cytokines (immune-regulating communication molecules)
  • Auto-immune

In holistic medicine we also consider:

  • Incomplete digestion (especially protein digestion).
  • Bbowel dysbiosis
  • Impaired liver function
  • Food allergies
  • Nutritional deficiencies
  • Stress appears to worsen the condition, and stress-reducing practices have shown to be helpful in these cases.

Each individual case of psoriasis should be considered as some combination  of these factors.

Conventional medical treatment:

Topical treatments such as steroid cream can greatly help or even “cure” psoriasis. Unfortunately, steroid cream can cause skin atrophy, stretch marks, spider veins and easy bruising when used long-term. The effects can also become systemic and disrupt hormone levels, contributing to osteoporosis and even psychosis.

Steroid creams don’t work for everyone, and there is often a decreasing effect of treatment with continual use. There can also be serious rebound effects with sudden discontinuance.

Immune-suppressive drugs such as cyclosporin and methotrexate are used, but liver, kidney and blood values must be monitored regularly because of the toxicity of these drugs.

Dr. Myatt’s Holistic Self-Help Recommendations

Diet and Lifestyle

Primary Support

  • Maxi Multi: 3 caps, 3 times per day with meals. Maxi Multi contains optimal (not minimal) doses of all essential vitamins, minerals, and trace minerals, including those often deficient in psoriasis.  The most important deficiencies in psoriasis are:
    vitamin A, vitamin E, chromium, selenium, zinc, and vitamin D.
  • Omega 3 fatty acids: especially EPA and DHA as found in fish oil. Target dose is 1.8grams EPA and 1.2 grams DHA. This can be obtained from:
    Max EPA
    : 10 caps per day with meals
    OR
    Maxi Marine O-3: 4 caps per day with meals
  • Maxi-Flavone: 1-2 caps per day with meals. This ultra-potent formula contains herbs which decrease inflammatory cytokines.
  • Vitamin D: additional vitamin D as needed to obtain optimal blood levels. Learn about vitamin D testing here. Optimal vitamin D levels are very important for psoriasis success.

Additional Support

  • Forskolin: 1 cap, 2 times per day. This herb help normalize
    the cAMP /cGMP ratio which is imbalanced in psoriasis.
  • Treat GI Dysbiosis if present (highly likely), best done with the results of a Comprehensive GI Health Profile. Treatment may include goldenseal (hydrastis), milk thistle, probiotics, and other gut treatments.

Lifestyle / Topical Treatments

  • Sunlight. UVB exposure has long been known to aid psoriasis  This could be due to increased vitamin D production.
    Newer prescription creams for psoriasis include synthetic vitamin D, further showing the importance of vitamin D for psoriasis.
  • Topicals (how to wash and protect psoriatic skin).
    Wash – Use mild, chemical-free soaps and cosmetics. Harsh alkaline soaps can cause further irritation.
    Moisturize – Chemical-free, gentle moisturizers should be applied after every shower or bath.
    Bathe – baths with baking soda, oatmeal or bentonite clay can be very soothing and detoxifying. Soak for 15-20 minutes in warm water. Do NOT use a bath for cleansing, only for soaking. Be sure that you are using pure, uncontaminated water! Be sure that you are using pure, uncontaminated water! If you are unsure about your water quality you may need to consider adding a water filter to your home.
    Shower
    – for actual skin cleansing, take a shower. Use chemical-free oatmeal soap, other mild soap or Dove brand bar soap. But please remember, when you’re hot (and your skin’s pores are wide-open), you can absorb toxins from the water. Shower-head filters are inexpensive and reliable.
  • DON’T pick or scratch skin! Psoriatic lesions tend to grow at the site of skin injury. If itching is uncontrollable, use a skin brush to gently exfoliate without causing dermal injury.
  • Drink pure water – A Good Water Filter is a Cheap Investment in Your Health. A reliable, highly-effective under-sink water filter is an excellent health investment, especially when you consider how important water is to health. The human body is about 60% water. That means we can have 60% of our total body weight contaminated with a variety of toxins if we drink lousy water.

    The highest-rated water filters cost about the same as the cheap junk. Aquasana Water Purifiers  makes some of the highest-rated filters at the best prices

Tests

Dr. Myatt’s Comments

  • Diet and balanced digestion / gut function are primary
  • Correcting nutrient deficiencies with supplementation and ensuring optimal vitamin D levels are also very important

ALL psoriasis patients, whether symptomatic or not, should pay special attention to cardiovascular and metabolic risks. I recommend looking at cardio risk factors including the “other” risk factors at a regular interval.

Psoriasis can be challenging, but starting with the basics (good gut, adequate nutrients) often corrects or at least greatly improves symptoms. When natural, corrective treatment is used, improvement in skin lesions can be expected to include improvement associated risks such as heart disease and diabetes.

Topical treatments alone, even when they decrease skin lesions, do not correct systemic risks. Psoriasis should therefore be treated as a systemic disease, not a skin disease.

References:

  1. Abou-Raya A, Abou-Raya S. Inflammation: a pivotal link between autoimmune diseases and atherosclerosis. Autoimmun Rev. 2006 May;5(5):331-7. Epub 2006 Feb 3.
  2. Boehncke WH, Boehncke S. Research in practice: the systemic aspects of psoriasis. J Dtsch Dermatol Ges. 2008 Aug;6(8):622-5. Epub 2008 Jun 16.
  3. Gottlieb AB, Chao C, Dann F. Psoriasis comorbidities.J Dermatolog Treat. 2008;19(1):5-21.
  4. Kaplan MJ. Cardiometabolic risk in psoriasis: differential effects of biologic agents. Vasc Health Risk Manag. 2008;4(6):1229-35.
  5. Ludwig RJ, Herzog C, Rostock A, Ochsendorf FR, Zollner TM, Thaci D, Kaufmann R, Vogl TJ, Boehncke WH.Psoriasis: a possible risk factor for development of coronary artery calcification. Br J Dermatol. 2007 Feb;156(2):271-6.
  6. Wakkee M, Thio HB, Prens EP, Sijbrands EJ, Neumann HA. Unfavorable cardiovascular risk profiles in untreated and treated psoriasis patients. Atherosclerosis. 2007 Jan;190(1):1-9. Epub 2006 Aug 30.
  7. Wu Y, Mills D, Bala M. Psoriasis: cardiovascular risk factors and other disease comorbidities.J Drugs Dermatol. 2008 Apr;7(4):373-7.
  8. Kourosh AS, Miner A, Menter A. Psoriasis as the marker of underlying systemic disease. Skin Therapy Lett. 2008 Feb;13(1):1-5.
  9. Gottlieb AB, Dann F, Menter A. Psoriasis and the metabolic syndrome. J Drugs Dermatol. 2008 Jun;7(6):563-72.
  10. Sommer DM, Jenisch S, Suchan M, Christophers E, Weichenthal M. Increased prevalence of the metabolic syndrome in patients with moderate to severe psoriasis. Arch Dermatol Res. 2006 Dec;298(7):321-8. Epub 2006 Sep 22.
  11. Puig-Sanz L. [Psoriasis, a systemic disease?] Actas Dermosifiliogr. 2007 Jul-Aug;98(6):396-402. [article in Spanish]
  12. Azfar RS, Gelfand JM. Psoriasis and metabolic disease: epidemiology and pathophysiology. Curr Opin Rheumatol. 2008 Jul;20(4):416-22.
  13. Gisondi P, Girolomoni G. Psoriasis and atherothrombotic diseases: disease-specific and non-disease-specific risk factors. Semin Thromb Hemost. 2009 Apr;35(3):313-24. Epub 2009 May 18.
  14. Shapiro J, Cohen AD, David M, Hodak E, Chodik G, Viner A, Kremer E, Heymann A. The association between psoriasis, diabetes mellitus, and atherosclerosis in Israel: a case-control study.J Am Acad Dermatol. 2007 Apr;56(4):629-34. Epub 2006 Dec 8.
  15. Cohen AD, Sherf M, Vidavsky L, Vardy DA, Shapiro J, Meyerovitch J. Association between psoriasis and the metabolic syndrome. A cross-sectional study. Dermatology. 2008;216(2):152-5. Epub 2008 Jan 23.

 

Rosacea

A Challenging Condition That Can Respond Well To Natural Treatment Approaches

There are four main subtypes of rosacea:

Ocular rosacea leaves sufferers with red, dry and irritated eyes and eyelids and symptoms including  itching and burning and feelings of having dust or grit or a foreign body in the eye.

Erythematotelangiectatic rosacea causes a permanent redness of the skin with a tendency to blush or flush easily and frequently small blood vessels are visible near the surface of the skin.

Papulopustular rosacea can cause some permanent redness with red bumps and / or pus-filled bumps or lesions which usually last for 1 to 4 days – this can be easily mistaken for acne.

Phymatous rosacea is most commonly associated with rhinophyma, an enlargement of the nose. Symptoms include thickening of the skin, irregular surface nodules or bumps, and enlargement. Phymatous rosacea can also affect the chin, forehead, cheeks, eyelids, and ears. As with Erythematotelangiectatic rosacea small blood vessels visible near the surface of the skin (known as telangiectasias) may be present.

So, what causes rosacea and what can be done for it?

Conventional Medicine does not recognize any one specific cause for rosacea – but has several theories which involve things such as Cathelicidins, elevated levels of stratum corneum tryptic enzymes (SCTEs), overgrowth of intestinal bacteria, Demodex mites (which may be increased in steroid-induced rosacea), stress, sunburn, temperature extremes, alcohol, caffiene, histamine intolerance, drugs, and steroids – which are often prescribed to treat other skin conditions. Unfortunately for Conventional Medicine there is no one simple test to diagnose rosacea – leaving Conventional Doctors in the difficult position of having to “do it the old way” – by actually examining and listening to their patient!

The response to rosacea by Conventional Medicine is equally predictable – for it involves throwing a variety of patented Big Pharma drug offerings at the problem in the hopes that something will work and provide relief. Antibiotics are ever-popular as is clonidine (an antihypertensive drug that is also used to help addicts withdraw from opiates!) and other antihypertensive drugs. Of course, if all else fails (or even before all else fails) some Conventional Doctors may fall back to their old faithful, steroids – despite the fact that steroids can actually cause rosacea symptoms for many people.

Some more natural approaches to rosacea include:

Methylsulfonylmethane (MSM) and Silymarin – which have been clinically examined and found to be of benefit. MSM, a biologically active form of sulfur has a long history of benefit to the skin and silymarin – a flavonoid found in Milk Thistle is a powerful antioxidant with a special affinity for the liver.

High potency fish oil has a valuable place in the treatment of rosacea, for the powerful antiinflammatory effects of Omega-3 fatty acids EPA and DHA.

Antiinflammatory flavonoids such as are found in Dr. Myatt’s Maxi Flavone could be expected to reduce inflammation since Maxi Flavone contains contains optimal doses of the flavonoid herbs which quench Radical Oxygen Species (ROS), lower TNF alpha and NK cell activity and decrease excess inflammation. Maxi Flavone is a potent formula providing support for immune function, circulatory health, liver detoxification mechanisms, and antioxidant pathways.

High dose Folic Acid and Vitamin C have been investigated and found helpful in some cases of rosacea.

Vitamin D is becoming increasingly recognized for it’s relationship to overall health and skin health – and many Americans are deficient in this important vitamin. Fortunately, Vitamin D testing is easy and accurate, and supplementation is safe and effective in restoring Vitamin D to healthy levels. A warning though: vitamin D and retinoic acid may promote expression of cathelicidin, which has been implicated as a causitive factor for some rosacea sufferers. Other researchers take an opposing view, feeling that Vitamin D may play an important role in treatment because of the cathelicidins.

There are many other herbs that have been tried in the treatment of rosacea, with varying degrees of success. What seems to work for one sufferer often shows little benefit for another – underscoring the importance of an individualized and holistic approach to each individual.

Finally, digestive factors appear to be very important in almost all cases of rosacea that we have treated here at The Wellness Club. Many sufferers are found to be deficient in hydrochloric acid – a problem which initiates a whole cascade of other digestion-related problems. Fortunately, Gastric Acid Function Self Testing is quick and easy and gives a very clear indication of a person’s gastric acid function. For those deficient in stomach acid, Betaine Hydrochloride can provide what may seem like a “miracle cure” to symptoms of rosacea.

Food allergies have also been implicated in rosacea – and many sufferers are well aware of certain foods that exacerbate their symptoms. For others, the allergens may not be so obvious, and Food Intolerance Testing may be indicated. In difficult cases further digestive system testing such as Gastro-Intestinal (GI) Health Profile with Parasitology to rule out bacterial and parasitic infections (remember, even Conventional Medicine is now grudgingly accepting that bacterial overgrowth may be a causative factor in rosacea) and Intestinal Permeability testing because of the relationship between intestinal permeability (AKA “Leaky Gut Syndrome”) and generalized inflammation and toxicity may be needed.

So there you have it: Rosacea can be an embarassing condition and difficult to treat – but a good holistic doctor who is willing to take the time and make the effort to work with a sufferer can usually work wonders!

References:

Berardesca E, Cameli N, Cavallotti C, Levy JL, Piérard GE, de Paoli Ambrosi G (2008). “Combined effects of silymarin and methylsulfonylmethane in the management of rosacea: clinical and instrumental evaluation”. J Cosmet Dermatol 7 (1): 8–14.

Yamasaki, Kenshi; Di Nardo, Anna; Bardan, Antonella; Murakami, Masamoto; Ohtake, Takaaki; Coda, Alvin; Dorschner, Robert A.; Bonnart, Chrystelle; Descargues, Pascal; Hovnanian, Alain; Morhenn, Vera B.; Gallo, Richard L. (2007)     Increased serine protease activity and  cathelicidin  promotes skin inflammation in rosacea Nature Medicine 13(8),  975-980.

Journal of Investigative Dermatology (2008) 128, 773–775. doi:10.1038/jid.2008.35 Vitamin D Regulation of Cathelicidin in the Skin: Toward a Renaissance of Vitamin D in Dermatology? Siegfried Segaert

Saturated Fats and The Big Fat Lie 


“For every complicated problem there is a solution that is simple, direct, understandable, and wrong.” — H.L. Mencken

 Everybody knows that saturated fats are unhealthy, just like everybody knew once upon a time that the earth was flat. The saturated fat myth has seriously compromised the heart-health of Americans, and it’s all based on a Big Fat Lie. Here’s how this fairy tale came to be….

How Bad Science (And Urban Health Legends) Get Started

Once upon a time, not so very long ago in a place called Nebraska (where the corn grows as high as an elephant’s eye) there lived a handsome young man who was very wealthy and powerful and kept himself very fit. This young man worked hard making millions of dollars in the construction industry and he loved to eat hamburgers. Though he was a very happy young man with a fine family and a successful business, all was not well. One day the young man became very sick. He suffered a heart attack, and almost died.

The young man’s doctors were very skilled and they saved the his life, but this turn of events frightened the young man very much and he set out to discover why such a dreadful thing happened to him. He found out that his blood cholesterol was high and his doctors told him that this was the cause of his heart attack. Without questioning whether this was true or not, the young man made up his mind to ensure that this would never happen again. He set out to learn as much as he could about heart disease and cholesterol, and quickly decided that the foods he was eating were to blame for his troubles. You see, the experts at that time believed that certain kinds of fats called saturated fats would cause high blood cholesterol and dangerous buildups of a substance called plaque in peoples blood vessels. The young man listened carefully to these “experts,” and being a fine young man who wished to help others avoid the troubles that he had experienced, he decided that he would do everything in his power to make sure that saturated fats never ever harmed anyone again.

The young man wrote many letters and spent much of his own money to take out big newspaper ads telling people how they were being poisoned by saturated fats. He made a lot of people believe in the same things that he believed – that is, that saturated fats were bad and would make them sick and had no place in a healthy diet. The young man’s efforts were quite successful and many big companies were forced to change the way they cooked their foods. They stopped using the saturated fats, and began to use fats that were created especially for them by big industries in big factories. They said that these fats were healthier, and the young man was pleased.

The young man became very popular, and dedicated the rest of his life to his mission of spreading the word about “bad saturated fats” and cholesterol to all who would listen. He didn’t live happily ever after, but he did live a long life, and became known as “America’s Number One Cholesterol Fighter” before he became sick with heart failure and passed away just a few years ago.

While this sounds like a fairy tale, it really isn’t. Philip Sokolof was a handsome and wealthy young man who suffered a heart attack that was blamed on high cholesterol and who dedicated himself and his millions to becoming a self-described “amateur cardiologist” and championing the cause of removing the saturated fats that he believed caused elevated blood cholesterol levels from the American diet. While his intentions were good, his science was shaky (he was a high school graduate, not a biochemist or a doctor – much less a cardiologist) and his misguided campaign resulted in the replacement of stable, healthy saturated fats with artificially created trans fatty acids that we now know as extremely dangerous “trans fats.”

Big Business (Can You Say “Proctor and Gamble”?) Helps Promote the Sat Fat Myth

While Sokolof was largely responsible for the vilification of saturated fats in America, he was not alone. The campaign against saturated fats actually began many years earlier, and Sokolof’s efforts were going on at the same time as the efforts from other political organizations were gathering momentum. A few years prior to Sokolof’s efforts, in 1986, the American Soybean Association began a campaign protesting the importation of competing palm and coconut oils. Two years later the “watchdog” organization, the Center for Science in the Public Interest, took up the cry against saturated fats with the publication of a booklet that was later found to contain mistakes, errors of biochemistry, and erroneous statements about the fat composition of foods. This concerted campaign against saturated tropical oils paid off, and ” fats” have been considered poison ever since by mainstream medicine and nutrition “experts.”

To discover why saturated fats have been given such a bad rap we need to go a little further back into history – perhaps as far back as the riverboat days of Mark Twain, but at least to the Second World War, when Japanese forces occupied much of the south Pacific and supplies of most of the tropical oils in the US were cut off for a number of years. Americans turned to home-grown substitutes: polyunsaturated oils such as corn, peanut, cottonseed, and a product of the aforementioned American Soybean Association, soy oil. As the use of these oils grew the growers and industries involved in their production became more powerful and eager to protect their market at any cost.

At this same time, in the early 1950′s, America began to notice a sharp increase in rates of cardiovascular disease and researchers were looking for answers. A study conducted by a Russian researcher found that rabbits, fed with animal fats (cholesterol) added to their feed developed fatty deposits in their skin and other tissues, including their blood vessels. (I’ll bet those normally vegetarian bunnies wondered what they were being fed!) Another sensational study relied on autopsies of American soldiers that had died in the Korean conflict and found that many of those examined had buildups of arterial plaque – atherosclerosis. (Which surely couldn’t have had anything to do with the military diet of the day, right? Or with the popularity of cigarette smoking?) This study, which made major news at the time, overshadowed other studies of the period which showed similar degrees of atherosclerosis in populations which had less mortality from heart disease despite high fat and high meat diets, or that ate far more vegetarian diets and suffered similar degrees of atherosclerosis, and generally indicated that the thickening of the arterial walls is a natural and unavoidable process. The press took the headline-grabbing autopsy results and ran with them using their usual logic of “the rooster crows every morning, and then the sun rises: therefore, the crowing of the rooster is what makes sunrise happen!”

During the 1960′s the attack on saturated fats continued with unabated vigor: despite scientific studies showing a decided lack of benefits companies such as Mazola and Proctor and Gamble promoted their vegetable oil creations as being especially healthy, and medical journals of the day promoted Fleischman’s unsalted margarine as being especially good for patients with high blood pressure. The American Medical Association was initially skeptical of all this hype but after the American Heart Association published its dietary guidelines damning animal fats and praising vegetable oils the AMA quickly fell into line. In 1966 a little self-help book called “Your Heart Has Nine Lives” advocated the substitution of vegetable oils for butter and other so-called “artery clogging” saturated fats. This book was sponsored by makers of Mazola Corn Oil and Mazola Margarine – no surprise – and was widely and freely circulated.

And that brings us to the handsome young man with his clogged arteries. Despite volumes of evidence to the contrary, saturated fats have been the “fall guy” for coronary artery disease since the 1950′s when in fact, as early as 1956 one researcher had suggested that the increasing use of hydrogenated vegetable oils might be the underlying cause of the CAD epidemic. Unwilling to stand idly by and let profits be imperiled by such things as health or humanitarian concerns, the massive and powerful edible oil industry in the United States has obfuscated, bullied, manipulated, and outright lied to protect it’s burgeoning market share. Supporting the flawed science of Philip Sokolof and pressuring legislators to adopt the anti-saturated fat / tropical oils legislation that he promoted was just good business.

Setting the Record Straight about Sat Fats

So, just what are these so-called saturated fats, where do they come from, and what are they used for? Well, the answers to these questions might be a surprise – sat fats are not what we have been led to believe. The most exact answers to the question “what is a saturated fat?” require some tedious and complicated science, and there are varying degrees of saturation. It is easier to simply think of the properties of “hardness” of fats.

A fat that is fully “saturated” would be as hard as wax, and quite indigestible. Fats that are almost totally “unsaturated” are very liquid, easily absorbed, and not at all common in the natural food supply. This “hardness” of fats is also dependant upon temperature. Many fats are liquid when warm, and solid when cold. Butter, for example, is quite hard when refrigerated, but soft at room temperature. Animal fats such as beef fat, lard, or chicken fat, while usually called “saturated fats” are actually not so: they are mixtures of naturally occurring fats and are actually less than half “saturated.” So-called “saturated fats” include things such as cocoa butter, dairy fats (milk fats and butter for example), palm oil, and tallow. Even breast milk is high in saturated fats! Monounsaturated fats include most animal fats, olive oil, canola oil, and peanut oil. Polyunsaturated fats include corn, cotton, and soybean oils, borage and primrose oil, flax seed oil, and fish oil.

Then there are the “modified” oils: oils that have been altered through a process called “hydrogenation” to make them more useful for certain applications. Margarine is a perfect example of hydrogenation: liquid oil such as cottonseed oil or corn oil, something that humans would never eat in nature, is altered to make it more solid and hard at room temperature. Crisco is another example – the name stands for CRyStalized Cottonseed Oil. The degree of hydrogenation is varied according to the desired use of the oil. Heavily hydrogenated oils might become stick margarine, while less hydrogenated or “partially hydrogenated” oils would become “spreads” or other “food products.”

Then there are the “trans fats” that have been in the news lately. These are fats that have had their molecular geometry altered, either on purpose or accidentally, and they are with very few and minor exceptions, not found in nature. Trans fats, when eaten by humans, tend to have some very bad effects on our bodies as they enter our cells and change how the cell walls function. Effects of trans fats in humans (and animals too) range from unfavorable changes in cholesterol levels to causing blood to become more “sticky”, to reduced ability to utilize insulin and increased blood sugar levels and increased weight, to alterations in hormone balances, and more. Trans fats are really only a very small step away from polyunsaturated fats – many polyunsaturated fats can be turned “trans” simply by heating them too much in cooking!

So, what does all this mean in more practical terms? It means that we must choose our fats carefully, and use them wisely. It means that we must cautiously weigh the claimed benefits of the vegetable-based hydrogenated “designer fats” that are so very commonplace in our modern “fast foods / prepared foods” diet against the known benefits of those traditional and natural fats that have been a part of mankind’s diet for millions of years.

We humans have evolved over the millennia as creatures that are well-adapted to, and in fact require, animal fats and proteins in our diets for optimal health – the claims of the vegetarian and vegan folks notwithstanding. Indeed, our very first meal, at our mother’s breast, supplied us with a high energy drink that gave our tiny bodies the cholesterol needed for development, and a special fat called Lauric Acid. This Lauric Acid, which is also found in the now-vilified tropical oils coconut oil and palm kernel oil has very strong antifungal and antibacterial properties and helps our tiny infant bodies develop strong immune systems. We are very well equipped to utilize fatty acids in the form of saturated fats such as dairy fats, and monounsaturated fats such as animal fats and olive oil. It is only with the advent of modern industrial processes that polyunsaturated fats such as corn and soybean oils have been available for our consumption – though fish oils (a form of polyunsaturated animal fat) have historically been considered to be healthy.

Why You Should Eat Butter and Lard

Butter, as another example, has a far healthier composition as a saturated fat than the synthesized creations that are the various margarines. Being a combination of saturated, monounsaturated, and polyunsaturated fats it is not as “stable” as margarine – that is, it will turn rancid (a form of turning “trans”) if not refrigerated. But then, who would eat rancid butter? It also contains a variety of health-giving vitamins, minerals, and other nutrients.

Does anyone remember the jar of bacon grease that was a fixture in every kitchen before the days of “spray-on” cooking oils, non-stick fry pans and fat-phobia? My mother carefully saved the grease from the morning bacon, and it was used to cook all sorts of wonderful things, from our morning eggs to delectable entrees and even desserts. We keep a jar of bacon grease in our own kitchen – it is far healthier than the canola oil and soy lecithin and “propellants” (your guess?) that are in our can of “no stick cooking spray.”

Then there is our obsession with “vegetable oils” as found in the aforementioned Crisco shortening. It is interesting to note that Proctor and Gamble, perhaps seeing the writing on the wall, or perhaps in a belated fit of conscience, has sold off the Crisco name and product. This “all vegetable oil” creation, once made from cottonseed oil, is now made from canola oil which must be hydrogenated (as was the cottonseed oil) to make it semi-solid. Smuckers, the new owners of Crisco, claims “Our entire line of Crisco Shortening products have been reformulated to contain zero grams trans fat per serving”. Can anyone reading this remember the days when lard was used? All-natural, no-trans-fat lard that made such wonderfully fluffy pastries and flaky pie crusts? Do we really think that humans are well-equipped to consume the kinds of oils that require bushels of rape seed or corn or soybeans per gallon to produce? Any more than we might be equipped to consume petroleum oils – no matter how they are “modified”?

Just like our handsome young man who made it his life’s mission to vilify healthful fats, we live in a fairy-tale world where we are led to believe that with a little help from chemistry and science we can fool mother nature into allowing us to consume “food products” that our bodies were never intended to have to deal with. Unfortunately, life in that fairy tale world is having very real and very serious consequences for Americans and people around the world who are buying into the anti-sat-fat fantasy being promoted by the vegetable oils industry. We are gambling our health and our lives and our future on a grand industrial experiment, and it is paying off with increasing rates of heart disease, cancer, diabetes, obesity, and more.

At the beginning of the last century, most of the fats in our forefathers diet were either saturated or monounsaturated, mostly from butter, lard, tallow, coconut oil and small amounts of olive oil. Today most of the fats in our diet are polyunsaturated from vegetable oils mostly from soy, as well as from corn, safflower and canola. Before 1920 coronary heart disease was a rarity in America, causing no more than 10% of all deaths. Today heart disease accounts for at least 40% of all deaths. Is there a connection? We believe there is, and a growing body of scientists, researchers, and health care professionals is beginning to stand up to the politically correct diet dogma that is dictating low fat diets and vegetable fats instead of animal or tropical fats. For a historically interesting end to this article we go back to 1956 when Dr. Dudley White, in a television interview, noted that heart disease in the form of myocardial infarction (heart attack) was almost nonexistent in 1900 when egg consumption was three times what it was in 1956 and when corn oil was unavailable. When pressed to support the low-fat, vegetable oil based “Prudent Diet”, Dr. White replied: “See here, I began my practice as a cardiologist in 1921 and I never saw an MI patent until 1928. Back in the MI free days before 1920, the fats were butter and lard and I think that we would all benefit from the kind of diet that we had at a time when no one had ever heard the word corn oil.”

Former surgeon general Dr. C. Everett Koop even said, during congressional hearings in 1988: “the coconut scare is foolishness. . . To get the word to commercial interests terrorizing the public about nothing is another matter.” Could it be that it is time to turn away from the dangerous designer oils and fats of Big Industry and return to the animal and tropical fats that served our ancestors so well? We think it is!

Finally, let’s look briefly at this current medical fad that demands that we reduce cholesterol levels in our bloodstream to the lowest possible levels. Remember, cholesterol is essential to life; so essential that your liver will make it “de novo” – from new – if your body senses that it doesn’t have enough of this precious material. Even conventional medicine, in the form of The Framingham Report – the oldest, longest, and biggest study into heart disease in history – determined that when total serum cholesterol is reduced below 160 the risk of heart disease actually increases. Even more interestingly, the Director of The Framingham Study, Dr. William Castelli said in the July 1992 issue of the Archives of Internal Medicine “At Framingham, we found that the people who ate the most saturated fat, the most cholesterol and the most calories weighed the least, were more physically active and had the lowest serum cholesterol levels.” We can only imagine the dismay that this information must have cause for Philip Sokolof; he must have been aware of it as it was published over a decade before his death. Nevertheless, Sokolof persisted in his efforts to vilify saturated fats and remove cholesterol from the American diet and we can only guess as to why he would continue these efforts in the face of research showing them to be wrong, even harmful. Was he simply too stubborn to accept the facts that proved him wrong, or was he too fully caught up in the whirlwind of Big Politics, Big Industry, Big Agriculture, and Big Pharmacy to be able to change? We’ll never know…

References
1.) Sokolof article http://www.cbsnews.com/stories/2003/11/26/health/main585849.shtml
2.) Sokolof death http://www.blogofdeath.com/archives/000902.html
3.) D Groom, “Population Studies of Atherosclerosis,” Annals of Int Med , July 1961, 55:1:51-62; W F Enos, et al, “Pathogenesis of Coronary Disease in American Soldiers Killed in Korea,” JAMA , 1955, 158:912
4.) “Hydrogenated vegetable oils might be the underlying cause of the CAD epidemic”
A Keys, “Diet and Development of Coronary Heart Disease,” J Chron Dis, Oct 1956, 4(4):364-380
5.) Excerpt from “The Coconut Diet: The Secret Ingredient That Helps You Lose Weight While You Eat Your Favorite Foods” by Cherie Calbom http://www.enotalone.com/article/3242.html
6.) http://easydiagnosis.com/articles/oiling.html “The Oiling of America” by Enig and Fallon – many rerferences following this 4 part series.
7.) http://www.westonaprice.org/knowyourfats/skinny.html#lipid
The Weston A Price Society Enig & Fallon article “The Skinny on Fats”
8.) Framingham Study reports re: total cholesterol <160:
“There is a direct association between falling cholesterol levels over the first 14 years and mortality over the following 18 years” (11% overall and 14% CVD death rate increase per 1 mg/dL per year drop in cholesterol levels). Anderson KM JAMA 1987
9.) The Honolulu Heart Study:
“Our data accord with previous findings of increased mortality in elderly people with low serum cholesterol, and show that long-term persistence of low cholesterol concentration actually increases the risk of death. Thus, the earlier that patients start to have lower cholesterol concentrations, the greater the risk of death.” Lancet Aug 2001.

 

Senior Health


Good Health for the Golden Years

Healthy, Active SeniorsAs I wrote in one HealthBeat article, “The ‘golden years’ can kiss my grits.” What I meant was that “The Golden Years” — that time in life when the family is raised and we are “hopefully” financially secure enough to stop working full time, and to travel or work at our favorite hobbies if we so choose — are often tarnished by failing health. I think that’s a pity, but it doesn’t have to be that way.

If you read the discussion on aging at the Anti-Aging Health Solution Center, you know that the human life expectancy should be on the order of 120 years. I’m not talking about just living long, either. I’m talking about spending those years in good health. Many people start crawling toward the grave from young or middle adulthood, plagued with aches, pains and illnesses. That’s not the way it is in many cultures.

By following some Basic Rules of Good Health and choosing natural, corrective measures over often-dangerous drugs and surgical “band aids,” a longer, healthier life is certainly possible.

Please visit these various areas of our site to find out how to be healthy and happy well into old age.

The Health Solutions Center at Left is a Great Place to Begin Your Search for Better Health.

Here are some additional articles for past HealthBeat News that you may find of benefit:

Neurological Disease: What You’re NOT Going to Hear From Your Conventional Doctor

Rejuvenate Your Heart in 9 Simple Steps

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Sex Hormone Balance:


For Serious Anti-Aging and Disease Prevention

In both males and females, a decline or imbalance of the sex hormones is associated with a wide variety of health problems.

Imbalanced or decreased sex hormones in women can cause:

  • Acne or oily skin
  • Bloating
  • Bone loss
  • Breast disease including cancer
  • Cancer (hormone-related: breast, ovary, uterus)
  • Decreased fertility
  • Depression
  • Endometriosis
  • Excess facial and body hair
  • Heart disease
  • Heavy or painful periods
  • Hot flashes
  • Irregular periods
  • Irritability
  • Loss of muscle mass
  • Loss of scalp hair
  • Low libido
  • Memory lapses
  • Menstrual irregularities
  • Mood swings
  • Nervousness
  • Night sweats
  • Osteoporosis
  • Polycystic ovarian syndrome (PCOS)
  • Poor concentration
  • Sleep disturbances
  • Tender or fibrocystic breasts
  • Urinary incontinence
  • Vaginal dryness
  • Weight gain

Imbalanced or decreased sex hormones in men can cause:

  • Bone loss
  • Decreased mental clarity
  • Decreased muscle strength
  • Decreased stamina
  • Decreased urine flow
  • Depression
  • Erectile dysfunction
  • Heart disease
  • Hot flashes
  • Increased abdominal fat
  • Increased urge to urinate
  • Irritability
  • Low sex drive
  • Mood swings
  • Night sweats
  • Poor concentration
  • Sleep disturbances

Youthful hormone balance, achieved with natural (“bio-identical”) hormone replacement therapy is considered a main-stay of anti-aging and longevity medicine.

Best Test for Sex Hormone Balance

The sex hormones can be tested in blood, saliva or urine. Urine provides the most accurate results, saliva is next best and blood testing is least accurate. Here’s why:

The sex hormones are released in “pulsed” doses throughout a 24-hour period. One hour, the output may be high, the next hour it may be low. This is a normal pattern for both sex and adrenal hormone excretion.

A blood sample gives us only a “photograph” of the hormones present at the time the blood is drawn. It tells us nothing about the 24-hour average of hormones (which is the real number we are concerned with). Blood testing is the least accurate measure of sex and adrenal hormones.

Saliva, which reflects an “average” of the 24-hour hormone content of the blood, is the next most accurate.

Because a 24-hour urine test “captures” both the highs and lows of hormone output for an entire 24-hour time period and averages them, this method of hormone testing is in my opinion the “Gold Standard” of hormone testing.

I currently recommend urine hormone testing for any patient who has concerns of hormone balance (which should be everyone over age 35-40!). Saliva testing is next best but does not appear to be as accurate.

What’s Your EQ?

Do you know what your EQ — estrogen quotient — is? You should, because this may be the single most important piece of information for preventing breast and prostate cancer. Here’s why:

Estriol (E3) is a “good” estrogen and higher levels of estriol are associated with less cancer risk. Estriol appears to block many of the effects of the carcinogenic estrogens, estradiol (E2), estrone (E1), and other related “pro-carcinogenic” estrogens. How do you find out if you have enough estriol to protect you from cancer? You calculate your EQ.

Studies done in the 19060’s and 1970’s showed that women with an EQ above 1.0 had a significantly lower risk of breast cancer. Many women today have EQ’s of less than 1.0, and breast cancer rates are on the rise. This is no coincidence.

Although the EQ ratio has been best-studied in women, it appears that a similar ratio may be predictive for prostate cancer in men.

I now recommend that my patients who have hormone testing done have the EQ performed at the same time. The results, if unfavorable, are easily improved with dietary changes, supplements, iodine therapy or other natural measures. Where cancer is concerned, “prevention” trumps “early detection” every time.

Learn more about urinary sex hormone testing, The “Gold Standard” of hormone testing, here: Comprehensive Plus Hormone Testing