CoQ10 (ubiquinone)

Super-Energizer and Potent Antioxidant

CoQ10 is a naturally-occurring antioxidant produced in the human body. It is vitally involved in energy production. CoQ10 functions as an “energizer” to mitochondria, the body’s energy producing units. Mitochondria, which produce energy the body’s “energy currency,” ATP, require CoQ10 to “spark” their production of energy units (ATP). Muscles, and the heart in particular, have high requirements for CoQ10.

CoQ10 is a potent antioxidant beneficial for:

• Heart Disease (angina, arrhythmia, atherosclerosis, cardiomyopathy, heart failure, congestive heart failure, myocardial infarction (1-18)
• High Blood Pressure (1,3,4,14, 53, 55)
• Neurological disease (Alzheimer’s, Huntington’s, Parkinson’s) (19-37)
• Immune deficiency and AIDS (40-45,52)
• Periodontal disease (38-39)
• Cancer (40, 44-49)
• Chemotherapy side-effects (50-52)
• Diabetes (53-56)
• Muscular dystrophy (57-58)
• fatigue / chronic fatigue / fibromyalgia (59-61)
• migraine headache (62-63)
• enhancing athletic performance (64-68)
• male infertility (69-73)

CoQ10 is produced by the body, but age, nutrient deficiencies, disease and some medications can lower the body’s CoQ10 levels. Cholesterol-lowering drugs (statins) deplete CoQ10. (15,54,74-77)

Studies have shown that the oil-preserved form is up to 3 times better absorbed than other forms. (78-80)

Although many claims are currently made for a “new” form (ubiquinol) being “more absorbable” than ubiquinone, this has never been proven or well-studied. Learn more about this issue here:Ubiquinone (CoQ10) versus Ubiquinol: Which Is Better?

CoQ10 and it’s use in CHF (Congestive Heart Failure):

http://www.ncbi.nlm.nih.gov/pubmed/19966871
“… Coenzyme Q10 (CoQ10) is essential for electron transport within the mitochondria and hence for ATP generation and cellular energy production. We recently demonstrated that plasma levels of CoQ10 are an independent predictor of survival in a cohort of 236 patients with chronic heart failure (CHF) followed for a median of 2.69 years. This is consistent with previous studies which have shown myocardial CoQ10 depletion in CHF, and correlated with the severity of the underlying disorder. Several intervention studies have been undertaken with CoQ10 in CHF, including randomized controlled trials with mostly positive outcomes in relation to improvement in plasma levels of CoQ10. A meta-analysis showed that CoQ10 resulted in an improvement in ejection fraction of 3.7% (95%CI 1.59-5.77) and the mean increase in cardiac output was 0.28 L/minute (95%CI 0.03-0.53). In a subgroup analysis, studies with patients not taking ACE inhibitors found a 6.7% increase in ejection fraction. The ongoing Q-SYMBIO trial will address whether CoQ10 supplementation improves survival in CHF patients. CoQ10 depletion may also be a contributory factor for why statin intervention has not improved outcomes in CHF. There is an emerging evidence base in support of CoQ10 as an adjunctive therapy in CHF.”

http://faculty.washington.edu/ely/coenzq10.html
“…The majority of the clinical studies concerned the treatment of heart disease and were remarkably consistent in their conclusions: that treatment with CoQ10 significantly improved heart muscle function while producing no adverse effects or drug interactions. …”

Dr. Myatt’s Conclusion:
CoQ10 is beneficial for nearly every type of Heart Disease (angina, arrhythmia, atherosclerosis, cardiomyopathy, heart failure, congestive heart failure, myocardial infarction (1-18)

Suggested dose:

50-100 mg per day for health maintenance and anti-aging / longevity programs.

200 to 400 mg per day for heart problems, cancer, weight loss programs and other indications.

Studies performed by the National Institutes of Health (NIH) using Vitaline ™ brand CoQ10, have used 300-400 mg (or more under medical direction) per day.

Each Capsule contains:

50 or 100 mg capsules are Wellness Club brand oil-preserved CoQ10 in easy to swallow gel Caps with Vitamin E & Beta carotene as natural preservatives.

300 and 400mg tablets are Vitaline/Integrative Therapeutics chewable wafers, the exact formulas used in the NIH Parkinson’s trials.Vitaline CoQ10

Vitaline brand CoQ10 is THE CoQ10 that has been the subject of NIH studies and a recent trial showing its potential value in Parkinson’s patients.

Co10 has been shown to be potentially helpful for:

• neurological health
• cardiovascular health
• anti-aging and longevity

THESE ARE ALL THE EXACT SAME PRODUCT That Is Used In The NIH Studies
All are made by Vitaline and given different labels.

Product # N334 Vitaline (60 chewable wafers 300 mg WITHOUT Vit. E)97.00

Vitaline, Vitamin E, and Vitamin E safety:

Some people (including some doctors) have a mistaken fear of Vitamin E, believing that “too much is dangerous.”

We have been unable to find any evidence in medical or scientific literature of any danger from taking large doses of Vitamin E. The National Institutes for Health (NIH) a US government authority places the maximum daily intake of Vitamin E at 1500 IU for healthy adults.

High intake of Vitamin E intake does tend to “thin” the blood, affecting coagulation by inhibiting platelet aggregation. People using antigoagulants or who bleed too easily may wish to discuss the use of Vitamin E with theri doctor.It has also been reported that Vitamin E in high doses may block the action of Vitamin K which is known as “the clotting factor.”

According to the label information and the Enzymatic Therapy website:

Vitaline® CoQ10 – 300 mg WITH Vitamin E contains 300 IU Vitamin E per chewable tab.

Vitaline® CoQ10 – 400 mg WITH Vitamin E contains 200 IU Vitamin E per chewable tab.

In order to achieve the daily intake of Vitamin E that you or your health care provider wish you to have you can either use a different tablet strength, either 300 or 400 mg to achieve 1200mg per day or mix your intake between Vitaline WITH and Vitaline WITHOUT Vitamin E to achieve your preferred daily intake of Vitamin E.