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Chitosan

Nature’s “Fat Grabber”

ChitosanChitosan is a weight-loss aid from the sea. Chitosan, a fibrous material derived from the outer shell(exoskeleton) of crustaceans, absorbs dietary fat and carries it through the G.I. tract without being digested. Chitosan also helps lower cholesterol levels. Unlike dangerous and ineffective diet drugs which have marginal weight-loss benefits, chitosan has proven more effective for weight loss. It also has been shown to lower blood pressure in weight loss studies.

Chitosan is also effective in kidney disease and kidney failure, helping prevent further deterioration of function.

Dosage: For weight loss, take 6 capsules at the beginning of a high-fat meal. Be sure to drink 8 ounces of water with each dose. For kidney failure, 3-6 caps, 3 times per day between meals or as directed by a physician.

Dr. Myatt’s Comment: Use with high-fat meals. Great support formula for weight loss plans. Because your body needs certain fats (Essential Fatty Acids), and fat-soluble vitamins, chitosan is not recommended for use at every meal, only high-fat meals.

Each capsule contains:

Serving Size: 4 capsules
Servings Per Container: 45

Amount Per Serving:

  • LipoSan ULTRA™ (high density chitosan marine fiber concentrate) 1000 mg
  • Citric Acid 300 mg
  • Lipase (3000 lipase units) 100 mg

Other Ingredients: gelatin, vegetable stearate

Contains ocean shrimp, soybean, wheat

Suggested Use: As a dietary supplement, take 4 capsules with 8 ounces of water, three times daily, before or immediately after meals, or as directed by a doctor.

Click here to
Order This Concierge Product Wellevate

This is a separate website and you will need to create a new account to order.

Related articles

Embarrassing Diet Drug Gets FDA OTC Approval

References:

1.) FDA News, February 7, 2007.http://www.fda.gov/bbs/topics/NEWS/2007/NEW01557.html
2.) Comparison of orlistat and sibutramine in an obesity management program: efficacy, compliance, and weight regain after noncompliance. Eat Weight Disord. 2006 Dec;11(4):e127-32.
3.) Efficacy and safety comparative evaluation of orlistat and sibutramine treatment in hypertensive obese patients. Diabetes Obes Metab. 2005 Jan;7(1):47-55.
4.) Baseline serum folate level may be a predictive factor of weight loss in a morbid-obesity-management programme. Br J Nutr. 2006 Nov;96(5):956-64.
5.) Drug treatments for obesity: orlistat, sibutramine, and rimonabant. Lancet. 2007 Jan 6;369(9555):71-7. Summary: There are no studies to show if these drugs are safe for long-term use.
6.) Effect of chitosan on renal function in patients with chronic renal failure. J Pharm Pharmacol. 1997 Jul;49(7):721-3.
7.) Effect of chitosan in complex management of obesity. Pol Merkur Lekarski. 2002 Aug;13(74):129-32.

L-Lysine

An Essential Amino Acid

Amino acids have many functions in the body. They are the building blocks for all body proteins – structural proteins that build muscle, connective tissues, bones and other structures, and functional proteins in the form of thousands of metabolically active enzymes

Amino acids provide our body with nitrogen that is essential for growth and maintenance of all tissues.

Because our body can’t make lysine, we must get it in the foods we eat. In people for whom wheat (breads) is the predominant food staple, lysine deficiency can occur, because only small amounts of lysine are found in grain.

Low dietary lysine may lead to overall protein deficiency symptoms, such as a compromised immune system and failure to grow, and also to heightened levels of stress and anxiety.

In the April 2004 issue of the “Proceedings of the National Academy of Sciences,” researchers reported that supplementing cereal-based diets with lysine reduced chronic anxiety and stress in a population that consumed wheat as a primary diet component. This suggests that Lysine supplementation may improve your mental well-being if this amino acid is lacking in your diet.

Though conventional medicine tries to claim there is no proof, many people report great success in using L-lysine to combat the herpes simplex virus that produces common “cold sores” and genital herpes sores. Lysine exerts it’s antiviral effects by inhibiting the replication of the herpes simplex virus. By holding the virus in check L-lysine may decrease the number of cold sores or genital herpes outbreaks, and it may also help the sores heal more quickly. Users find that supplementing with 1 to 3 grams of lysine each day may limit recurrences, and taking it as soon as symptoms are noticed may reduce the length of time that herpes outbreaks last.

Since the virusis similar, some practitioners and researchers feel that L-lysine may have a beneficial effect toward reducing outbreaks of herpes zoster or “shingles.”

There is also evidence that L-lysine may be helpful in alleviating post-herpetic neuralgia.

L-lysine can help the gastrointestinal tract absorb calcium and reduce how much of this mineral is excreted in urine. Supplementing with both lysine and arginine, another protein-building amino acid, stimulates the cellsthat build new bone tissue. This combination of amino acids can also increase the synthesis of collagen, a structural protein important in maintaining the health of connective tissue, including cartilage, tendons and skin.

It should be noted that arginine is contra-indicated for those with the herpes virus as it can precipitate herpes outbreaks.

L-Lysine 500mg 250 caps # N263 – $19.95

Enter Quantity Desired and Click “Add To Cart” Button

Supplement Facts:

Serving Size: One (1) Capsule

Servings Per Container: 250

Amount Per Serving %DV: L-Lysine 500 mg **

** Daily Value Not Established. Percent Daily Values are based on a 2,000 calorie diet.

Other Ingredients: Cellulose, Gelatin Capsule, Stearates (Vegetable Source)

Directions: As a dietary supplement, one (1) capsule daily, or more as directed by your healthcare professional. Keep out of the reach of children. Store in a cool, dry place.

References:

Lysine fortification reduces anxiety and lessens stress in family members in economically weak communities in Northwest Syria. http://www.pnas.org/content/101/22/8285.full

Lysine – University of Maryland Medical Center http://umm.edu/health/medical/altmed/supplement/lysine

HealthBeat News

In This Issue:

The Product EVERYONE should have on hand! This simple, inexpensive supplement can protect you from a serious consequence of radiation and nuclear fallout. Remember Chernobyl?

Skin Rejuvenation Protocol. Find out the best methods for renewing a youthful appearance to skin. Dr. Myatt summarizes the research, then puts it all together in a comprehensive “Skin Renewal” program. A MUST for Summer skin care!

Member News and Notes

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The Product EVERYONE Should Have On Hand!

ARE YOU PREPARED FOR A RADIATION EMERGENCY?

Potassium Iodide (KI) Can Shield You From Thyroid Cancer

With 103 active commercial nuclear reactors in the United States, we live in constant threat of a nuclear emergency every day. A terrorist attack on any one of these facilities, or the release of a “dirty bomb” is also a possibility in today’s “highly charged” world. In fact, in an emergency, if you live within 200 miles of a nuclear reactor, you have a high risk of being exposed to significant doses of radioactive isotopes. In the event of a nuclear accident or attack radioactive materials can be released into the atmosphere, a high percentage of which is radioactive iodine. When a radioactive iodine cloud passes through a populated area, the radiation is concentrated into the thyroid gland of those exposed. The result is irreparable damage to the thyroid, which can lead to cancer. The 1986 Chernobyl accident in the Ukraine is a tragic example.

The best protection against thyroid damage and thyroid cancer induced by radioactive iodine exposure is Potassium Iodide. This simple compound protects the thyroid by saturating all of the iodine binding sites in the gland, leaving no room for the binding of radioactive iodine. Potassium Iodide is a low-cost way to protect yourself and your family against the long-term consequences of exposure to radiation. When used correctly, potassium iodide tablets can prevent or reduce the amount of radioactive iodine taken up by the thyroid gland. Even the government and the military stocks up on potassium iodide in case of nuclear disaster.

The body can’t distinguish between radioactive and the benign version of iodine, which is necessary for thyroid function. Taking 130 mg of potassium iodide, the dosage widely recommended for the blocking of radioactive iodine in the event of a nuclear disaster, can quickly and completely protect the thyroid gland, which is one of the organs most commonly damaged by radioactive fallout. Dr. Myatt’s Wellness Club offers a supplement that contains 14 x 130 mg tablets of potassium iodide. Tablets are scored for easy breakage in the case of any need for dosages smaller than 130 mg, as recommended for children and pets.

How many packages do you need?

The FDA recommends that you have one package per person available.* Remember that during an emergency, you may not be able to get to your home, thus it is recommended to have packages stored in several places as well. Since the shelf life of this product is virtually unlimited, you should have to purchase your supply only once. Have this on hand for your family, and remember the children, pets, grandchildren, too!

* To view home preparation procedures for emergency administration of potassium iodide, visit the FDA website at http://www.fda.gov/cder/drugprepare/kiprep.htm Only take potassium iodide tablets when guided by health officials in your area and follow guidelines included with each bottle.

Skin Rejuvenation Protocol

The skin (integument) is the body’s first line of defense in protection from the external environment. If it also one of the first things people notice about us. Healthy skin is both a cosmetic blessing and a sign of a healthy underlying system, yet few people know how best to take care of this important organ. Let’s focus on some of the most important things we can do to protect this amazing bit of our architecture!

A Basic Regimen for Skin Care

    1. Nutrition: Beauty from the Inside Out. Healthy skin requires water, essential fatty acids and nutrients to be truly healthy. No amount of topical cosmetics will make up the difference to skin that is under-nourished. The skin requires the following:

A.) Water ! The body is 60% or more water. Even a subtle dehydration makes lines and wrinkles appear deeper, whereas being well hydrated “plumps” skin and minimizes the appearance of lines. Drink 64 ounces of PURE water per day, especially in the Summer,

B.) UV Light: Small amounts of UV are beneficial to the skin, but excess amounts can cause premature aging and contribute to skin cancer. Ten minutes of early-morning sun several times per week is sufficient for skin health. Beyond that, always wear a UVA/UVB sunscreen with an SPF of 15, especially on the face.

C.) Smoking (and second-hand smoke): Causes a constriction of the small blood vessels that bring nutrients to the skin, depriving skin of both water, vitamins and minerals, and fatty acids. Smoking is one of the absolute WORST things you can do to skin. Don’t go there!

D.) Nutrients:

  1. Multiple Vitamin/Mineral Supplements: An optimal vitamin/mineral/trace mineral formula such as Maxi Multi supplies the important micronutrients required for healthy skin.
  2. Essential fatty Acids: The skin needs essential fats from the inside out to stay moisturized. EFA’s are supplied by flaxseed oil, flaxseed meal, or fish oil. Be sure to take 1-2 TBS of flax oil or 3 Caps of fish oil per day, and include fatty fish such as salmon in the diet twice per week. (You’ll learn more about Essential fats in upcoming installments of The New Keto Diet).
  3. Grape seed extract: 50-100 mg, 2-3 times per day is an optional “metanutrient” that aids the skin by improving collagen formation (the underlying structural material of skin) AND by acting as a potent antioxidant to protect skin from oxidation. (The human equivalent of “rust”!)
    1. A Basic Regimen for Skin Care

I.) Cleanse: The purpose is to gently remove surface debris without stripping natural oils. Most soaps are highly alkali and strip skin of natural oils. Wash skin twice per day in a mild soap like Dove or Ivory (both are highly recommended by many dermatologists).

II.) Skin Cream: Proven ingredients helpful for topical application include antioxidants (A,C,E, alpha lipoic acid) in a form that is easily absorbed by the skin (micronized). Glycolic acid helps break down old cells so they can be replaced more quickly with new cells from beneath. DMAE (dimethylaminoethanol) helps firm sagging skin, NaPCA aids moisture retention and Sunscreens that protect from UVA, UVB, and UVC are all useful in keeping skin radiant.

I have found it difficult if not impossible to find a good cream that contains all of these important ingredients until now. Rejuvenex is the first cosmetic preparation that I am aware of to combine the finest, proven ingredients into one easy formula. You can try to duplicate all of these skin essentials yourself, but you will be working hard and paying far more for the individual preparations. (Believe me, I know from experience. That’s how I’ve been making my own cream until now!).

In order to introduce you to the benefits of this formula, plus help you get started on a skin rejuvenation and protection program of your own (especially important as the Summer sun heats up), we have special-purchased Rejuvenex so we can offer it to you at a lower introductory price.

This cream is rich, wonderful, contains “all the right stuff” as listed above, and more, and a little goes a long way. You need only apply it morning and evening to get great results. Both men and women will benefit. As an alternative, you can do as I was doing and mix your own ingredients, just be sure to include the above-listed items for best results.

To order Rejuvenex, CLICK HEREor call 1-800-376-9288

Telephone Consultations with Dr. Myatt

Telephone Consultations
with Dr. Myatt

Get Fast Health Answers from a Natural Health Expert OR a Doctor-Designed Advanced Natural Health Program In the Comfort and convenience of Your Own Home

Would You Like to Turn the Clock Back 10 Years or More
And Have a Brand-New Lease on Life?

  • Brief Telephone Consultations (20 minutes)
  • General Health and Wellness Package
  • Health Recovery Program
  • Health Optimization Program (Anti-aging and Longevity)
  • Advanced Disease Rescue

What Natural Medicine Can Do for You — That Conventional Medicine Can’t

Modern conventional medicine performs amazing “heroic” care. If your broken body is found at the site of a serious car accident, conventional medicine’s ability to air-lift you to a hospital, CT scan you, set and pin broken bones, and keep you on life-support while you heal is what high-tech conventional medicine does best. And we are great at that — probably some of the best in the world.

But modern conventional U.S. medicine is NOT the best at everything. It it NOT the best solution for most day-to-day problems and most diseases. If it were, we would have some of the longest life expectancy — and health expectancy —- in the world. Yet here’s what the statistics show about health in the U.S.A.:

  • Americans spend 17+% of their GNP for health care, more than any other country in the world.
  • Life expectancy in America ranks 49th in the world, lagging far behind many countries who spend far less than we do for health (disease) care. (1)
  • Sixty-eight percent (two-thirds!) of Americans are overweight, thirty-three percent of these SEVERELY overweight (obese). (2)
  • Over ten million Americans take anti-depressants.
  • 50 percent of people over 85 will have Alzheimer’s Disease.
  • * Someone dies of heart disease every 34 seconds.
  • * One in six Americans suffers from an Anxiety Disorder.
  • * One in six Americans is either pre-diabetic or diabetic.

Modern medicine is an all but complete failure at curing or controlling chronic diseases such as cancer, heart disease, diabetes, obesity and anxiety/depression. Instead, the best conventional medicine can offer is a temporary “patch” for the major diseases of our time. In many instances, such as cancer treatment, the “medicine” often kills the patient before the disease would.

Beyond Conventional Drugs and Surgery — Natural Medicine Treats the Cause, Not Just the Symptom

Natural medicine and lifestyle counseling can prevent and reverse disease. This is because natural medicine looks for the cause of disease instead of merely treating symptoms. For example: depression has never been shown to be caused by a Prozac deficiency! But B complex vitamin deficiencies, lack of precursor amino acids (which are necessary to manufacture neurotransmitters), food allergies, heavy metal or other toxicities and emotional factors can all cause depression. Why mask a problem when the cause can be found and corrected? Genuine cure is more profound and certain than a Band-Aid will ever be.

Natural Medicine Treats the Patient, Not the Disease

No two people with the same disease have that disease for the exact same reason. Therefore, there can be no effective “one size fits all” medicine, yet this is how we are trained to treat people in the conventional medical model. For example: one person with irritable bowel syndrome is suffering because of a food allergy. Another may have the exact same diagnosis because of a lack of gastric acid function. A third may have IBS because of a yeast overgrowth in the colon. Yet the drugs prescribed for each of these patients is the same. Does this seem right to you?

Dr. Myatt Isn’t “Against” Drugs! (Especially Safe and Effective Ones)

Dr. Myatt practice complementary, integrative medicine, which means that she will use or recommend the best available treatment from both conventional and natural medicine. When  a drug or surgery seems like the best option, that is the advice she will give you.

If in her opinion you will benefit from a drug, that is what she will recommend and prescribe.

So often, however, our conventional drugs and treatments cause more harm than good. As a Naturopathic Medical Doctor, Dr. Myatt is trained to look for the cause of disease. Once the cause is known, there is opportunity for a genuine cure. The cure almost always entails natural methods, such as good nutrition, eliminating aggravating factors and restoring the body to a state of balance. These things are rarely if ever accomplished by drugs alone.

Dr. Myatt Finds “The Rest of The Story” that Modern Medicine Overlooks

If a person has a clear-cut set of symptoms, conventional medicine is good at giving the problem a name. We call this “diagnosis.” Just because we have named the problem does not imply that we know the cause, and in conventional medicine, it doesn’t even mean that we continue to look for a cause. You suffer from arthritis? There — we’ve got a name and we have a small collection of drugs that we will try until you feel pain relief. When your pain stops, our work is done. If none of our drugs stop your pain, oh well, we’ll just keep trying different drugs in different combinations.

The problem with this method of diagnosis and treatment is several-fold. First, because we are treating symptoms and not the cause, we might not be able to “cure” the problem with any of our available drugs. Secondly, since the treatment is a band-aid and doesn’t address the cause, the underlying problem is still going on with all the associated negative physical consequences. Finally, the drugs themselves usually have adverse consequences, up to and including death. Conventional treatment might offer some temporary pain relief, but at what cost?

Dr. Myatt looks for “the rest of the story.” If your diagnosis is arthritis, wouldn’t you like to know why your joints are deteriorating? The “wear and tear” theory has never been proven to be a cause of arthritis. Elderly marathon runners suffer far less arthritis than age-matched non-exercisers.

Is it a lack of bone and joint nutrients in the diet? An excess of inflammatory substances in the blood (which also increases heart disease and cancer risk)? A food allergy? Excess of a toxic substances or heavy metals? Once the underlying cause or causes are found, we not only have a better idea of how to stop pain, we have a genuine shot at a cure. And the side effects from natural remedies are that other complaints are often also corrected! Good things happen when we look for and treat the cause of a problem, not just the symptoms.

When No One Knows What’s Wrong

In conventional medicine, if your complaint fits into a neat little category that we can give a name to, we also know the drugs or surgeries that we are supposed to prescribe. They are in “the doctor cookbook.” But what if you have vague or unusual symptoms that don’t fit into any existing diagnosis?

If you have good insurance, you’ll get ATKTM — All Tests Known To Man (or all tests know to modern medicine). You may find yourself being CAT-scanned for an irritable bowel complaint and MRI’d for joint pains. Such ATKTM only rarely finds an anatomical cause for disease, and it NEVER locates a functional cause of disease.

Diagnostic tests are supposed to complement the doctor’s comprehensive evaluation, helping to “rule in” or “rule out” a suspected cause. Today, however, many physicians order tests in lieu of careful case study and patient evaluation. This “hit and miss” method of diagnosis is expensive, time-consuming and rarely productive. And when ATKTM comes back negative and you still have the complaint, then what? For conventional doctors it’s time to give you a “head med,” because if modern medical tests haven’t shown anything, the problem must be in your head.

The natural medical approach, which is Dr. Myatt’s approach, is to do a meticulous case study. By reviewing your symptoms, lab work, lifestyle and diet histories, family and personal medical histories, she is able to develop a solid “rule out” list of possible causes of your complaint.

Next, medical tests are ordered if they will rule in or out each of the items on the list. Like peeling the layers of an onion, she carefully explores the potential causes of your complaint until she finds it. In rare cases finding a cause is impossible, but most times it is merely difficult!

Using a combination of both conventional and alternative diagnostic measures, Dr. Myatt is able to find answers for many people who have been “given up on” by conventional medicine.

Why Dr. Myatt is The Doctor of First Resort — Prevention is Easier than Cure

Or stated differently, “If it ain’t broke, fix it before it breaks!”

Dr. Myatt and her team specialize in Health Optimization — making diet, lifestyle and other changes to prevent disease before it can establish a foot-hold.

Why wait until you have diabetes to make positive diet changes? Early signs, symptoms and lab abnormalities can predict your risk factors for many diseases years before they appear. The easiest time to correct a problem is before it even gets started. This is known as “preventive medicine,” and it is one of Dr. Myatt’s specialties. In the case of Health Optimization, a yearly review of your diet, symptoms, and lab results are recommended. From this, Dr. Myatt formulates a “Health Optimization Protocol” which is your personal guide to continued wellness for the coming year.

And Why She Is The Doctor of Last Resort — For “The Incurables” 

Prevention is always easier than cure, but perhaps you are past the point of prevention. If you already have a medical condition — even a serious one — Dr. Myatt can help. Her patients include people with advanced metastasized cancer, life-threatening heart conditions, autoimmune problems, neurological diseases and numerous other “incurable” problems.

With careful case-study and evaluation, Dr. Myatt makes health and life-saving recommendations to patients with all types of serious medical conditions.

Dr. Myatt’s patients have proven time and again that “where there’s life, there’s hope.”

Anti-Aging and Longevity Are Within Reach

Scientists estimate that the genetic lifespan of humans should be on the order of 120 years, yet the average US life expectancy for men and women is in the 70’s (and we rank 49th in the world for life expectancy).

For those who manage to live to 70’s 80’s and beyond, the way is often fraught with disease and disability for the last 20 or more years of life (the number of years of life spent in good health is known as “Health Span”). Why are we falling so short of our genetic potential for both lifespan and healthspan, in spite of the fact that we spend more on “health care” than any other nation on earth?

Modern medicine doesn’t really deliver “health care.” Instead, it is a model of “disease care,” waiting for a problem to happen  before taking action. Even then, the “action” taken is usually a Band-Aid instead of a cure. When it comes to prevention, health optimization and advanced methods of life extension, conventional medicine is woefully inadequate.

By identifying obstacles to good health and utilizing the vast body of longevity-enhancing techniques available, it is possible to extend both lifespan and healthspan. Much more is known about anti-aging and longevity than we currently utilize in conventional medicine.

Fortunately, alternative and complementary medical practices take advantage of this knowledge. Anti-aging and Longevity is one area of special interest and study for Dr. Myatt. She can help you know how to take advantage of your genetic potential for long life and good health.

You Can Consult Dr. Myatt In The Comfort of Your Home…. by Phone

Health Optimization requires careful medical detective work. Dr. Myatt evaluates your family history, personal past medical history, diet, lifestyle, risk factors, symptom profile and physiological stressors. She carefully reviews your laboratory reports and medical records, all pertinent medical data, and medications. Finally and most importantly, she listens carefully to your description of symptoms, complaints, and health goals. All of these factors are carefully weighed as Dr. Myatt and her medical team perform an exhaustive evaluation of your case.

Following your telephone consultation and case study by Dr. Myatt, you will receive your personalized Health Optimization Protocol. This report will include specific recommendations for diet, exercise, nutritional supplements, herbs and other conventional and/or complementary care — a complete “action plan” to put you on the path to Optimal Health, whether you are already healthy and looking to stay that way, or you suffer from a serious medical condition, or something in-between.

How Can Dr. Myatt Help Me Without Seeing Me in Person?

Dr. Myatt’s care does not replace your personal general physician. In fact, she insists that everyone have a personal family doctor in their local area. When the need arises, you should have someone locally who can listen to your lungs and heart with a stethoscope, perform routine examinations and stitch up boo-boos. Everyone needs a general family physician.

Dr. Myatt practices the advanced medical specialty of holistic and integrative medicine. Her evaluation of your case will go far beyond the type of medicine practiced conventionally. And because Dr. Myatt is also trained in conventional medicine, she can review and incorporate your conventional medical evaluations as part of your comprehensive work-up.

If you have asthma, for example, your local physician or health professional will have already listened to your lungs, referred your for breathing tests and prescribed medication. Dr. Myatt does not need to repeat this basic medical evaluation. She will, however, refer you to the appropriate type of medical practitioner when it appears that you have not had the complete “look” that should have been done. And she may suggest additional testing which has not been done by your conventional physician if it appears appropriate and necessary. This is all arranged by distance. Dr. Myatt writes prescriptions and lab orders for patients in every state and in countries around the world.

How Do I Enlist Dr. Myatt’s Services?

Use this link to schedule a brief telephone consultation. After you have completed purchase of your brief consultation, Dr. Myatt’s office will be in touch with you via email to schedule a time for this initial visit. Brief consultations can usually be scheduled quickly, usually within a matter of days.

All advanced patient programs begin with a brief telephone consultation. During this time, you will discuss your case with Dr. Myatt so that she can advise you as to which program / patient track is best suited to your unique situation.

If you elect to become a patient of Dr. Myatt’s after this initial visit, the cost of your brief phone consultation will be deducted from your program fees.

Next Steps: If You Are Accepted As a Patient

Before your initial one-hour intake visit, you will be asked to complete the following:

Patient information – This form explains your relationship with Dr. Myatt, and how you will work together towards your best health ever.
Authorization to Release Medical Records – This form, signed and given to your other health care providers will allow them to send your medical records to Dr. Myatt for her study and analysis.
Patient Registration and Comprehensive Intake – This form sounds simple, but here you will provide a great deal of information about yourself, your health, family history, medical history, diet, history of current illness and what you wish to achieve as you work together with Dr. Myatt.
Comprehensive Symptom Survey – This 9 page health questionnaire and symptom survey will make you think hard. By completing it fully and honestly, you will provide Dr. Myatt with valuable insights to your body systems and clues to help her in her investigations as she develops your personalized Health Action Plan.

Copies of available medical records should be included (a records request form is included in case it is needed).

On the appointed day and time, Dr. Myatt will call you for your appointment. This initial “visit” is one hour long. Your Health Optimization Protocol will be mailed to you several days to a week later (to allow sufficient time for case study) and will contain a complete set of instructions and recommendations for everything needed to begin a healthier lifestyle.

Follow-Up and Ongoing Care

Everyone has different needs, hence the different levels of programs and services. A person with advanced heart disease or cancer will require much more contact and ongoing monitoring that a healthy person seeking to improve further on their good health. These factors are taken into account when Dr. Myatt advises which level of service your care requires.

Unless you are quite healthy and simply seeking expert advice on the best diet and nutritional supplement program, you will need to follow-up with Dr. Myatt via phone and internet (email) to insure proper execution of your program.

Adjustments and corrections may need to be made to your protocol, depending in large part on how you respond to treatment, your ability to follow the program as closely as possible, and other intervening factors. Dr. Myatt has taken the requisite follow-ups into account in the various levels of service she provides.

Your care will include follow-up and a “retainer”-based program for the email answers and other feedback you may need to keep you moving toward health at the fastest, most effective pace.

How Come Dr. Myatt Charges More Than Other Doctors?

She doesn’t. A specialist who sees you in-office for 15 minutes, for example, may charge $90. However, after you leave the office, this doctor spends no additional time reviewing your case.

Dr. Myatt will spend an initial hour discussing your health concerns, then she and her team go to work studying your case, including review of all relevant medical data. This “case study” typically takes from 4-12 hours depending on the nature and complexity of your health concerns. This often involves not just case study but also medical research on your behalf. Then and only then does Dr. Myatt create your “Recommendations,” a complete, written protocol for you to follow. When you consider the level of time, care and attention that each patient receives, Dr. Myatt’s fees are a bargain.

Why the “Retainer” and Pre-Paid Follow-Up Visits?

Dr. Myatt has found that the inclusive follow-ups and retainer program is in the best interest of her patients for the following reasons:

  1. Patients who have made a commitment are more likely to follow through. Follow-through produces positive results.
  2. Prevents “treatment failures.”  The initial recommendations are a solid “starting place” for good health, but the program must be adjusted and “tweaked” as circumstances change, new information becomes available and patient health improves.Some patients, after paying the initial consult fee, either drop out (fail to follow-through) because they don’t want to incur additional visit expenses OR because they expect unlimited email follow-up at no charge.By incorporating the predicted follow-up visits into program costs, patients are far more likely to follow-up. Making the necessary “course corrections” with Dr. Myatt’s careful guidance produces far better results than an initial visit with no follow-up.
  3. Get the answers you need — ALL of them. Your program fees include significant email follow-up. Got a question? No reason to stumble on your health program, get bad advice off the internet, or simply let a question go answered. All you have to do is email Dr. Myatt and she will respond with the information, assurance and guidance you need to keep you on track to a healthier life.
  4. Better cost predictions. How much will that “only $90” visit cost if you have to return to the doctor dozens of times over the same health concern? Costs for holistic care can add up to a big “unknown.” Although it is possible that a person may exceed their annual program allowance with Dr. Myatt, this is unusual. By having pre-paid for your care and follow-up, you can have a much better idea of what your advanced holistic care will cost.

Can Anyone Become a Patient? Why Does Dr. Myatt “Screen” New Patients?

Dr. Myatt is big on results, something even her advanced cancer patients will attest to.  Because of this, she is very particular about who she will accept as a patient. Only those who seem truly ready to put forth the necessary effort to get well, or improve health, are accepted.

And because each individual patient is given so much time and attention, Dr. Myatt must necessarily limit her services to only as many patients as she can truly devote herself to at any one time. When you are under Dr. Myatt’s care, you can rest assured that you are being watched over very carefully. She does not “spread herself thin” and accept more patients than she can be totally devoted to.

There are also some patients who have ideas and desires that would make them unsuited to Dr. Myatt’s method of practice.

For example, Dr. Myatt is a firm believer in scientific holistic medicine. She does not practice “esoteric” or unproven techniques although she is familiar with most of them. Patients who want “chakra balancing,” “aura cleansing” or recommendation of nutritional supplements by crystal pendulum dowsing would not be happy with Dr. Myatt’s highly scientific, well-researched and proven methods of practice.

How Dr. Myatt’s Health Optimization Program is Different from other Healthcare Practices

  • Dr. Myatt takes the time to listen. No “quickie” initial or follow-up visits. Dr. Myatt takes the time to truly listen to your symptoms, complaints, questions and health goals. She and her team also spend an extensive amount of time reviewing your individual case. Very few physicians — even holistic and naturopathic practitioners — spend so much time entirely devoted to each individual patient.
  • Dr. Myatt and Team perform an in-depth analysis for each patient. Our testing is typically more comprehensive than traditional laboratory testing. We use “optimal,” not just “normal” values for lab interpretation. We look beyond the bounds of conventional “disease diagnosis” and try to truly understand the underlying causes and imbalances contributing to an individual’s symptoms.
  • “Tolle causum” — treat the cause. We are totally devoted to discovering the “hidden causes” of your health challenges in a way that goes far beyond conventional medical diagnosis and treatment. From this, we develop a customized treatment plan exclusively for you. No two people, even with the same diagnosis, will have the same treatment plan because all of our work is highly individualized.
  • “Vis Medicatrix Naturae” — with the healing power of nature. The human body is, to a great extent, self-healing when given the proper conditions. We cooperate with nature by using TLC — Therapeutic Lifestyle Changes — and natural remedies to stimulate the body to heal itself.

Modalities that Dr. Myatt Uses to Treat Disease and Optimize Health

Dr. Myatt is trained and licensed in conventional medical treatment including convention laboratory and physical diagnosis of disease. She can write prescriptions for drugs, deliver babies, commit surgeries, and sign death certificates.

However, her primary methods of treatment — “Vis Medicatrix Naturae” — include:

  • Diet and nutrition / nutritional supplements
  • Botanical medicine
  • Exercise and fitness programs
  • Bio-identical hormone therapy
  • Detoxification programs
  • Immune Enhancement
  • Lifestyle Counseling

Dr. Myatt’s Specialties Include:

  • Anti-aging and Longevity Medicine
  • ADD / ADHD
  • Auto-immune Disease
  • Heart Disease Prevention and Reversal
  • Cancer Prevention and Treatment Options
  • Natural (bio-identical) Hormone Replacement Therapy
  • Diabetes Managements and Type II Diabetes CURE
  • Anxiety, Depression and other Mood Disorders
  • Adrenal and Thyroid Dysfunction
  • Weight Loss and Maintenance
  • Digestive Difficulties (IBS, constipation, diarrhea, GERD)
  • Osteopenia / Osteoporosis
  • Infertility
  • Health Optimization
  • “Real” — Carefully Researched And Considered — Second Opinions

What Level of Care Best Suits Your Needs?

Health and Wellness Review 1 *Health and Wellness Review 2 *Anti-aging / Health OptimizationHealth Recovery ProgramAdvanced Health Rescue
Who is this for?People with no diagnosed disease and minor or no health problems who want an holistic review of their diet, lifestyle, and recent medical (lab) reportsPeople with diagnosed disease and minor to moderate health problems who want an holistic review of their diet, lifestyle, and recent medical (lab) reportsHealthy people (no disease) who want to optimize their health further and implement an anti-aging programPeople with health problems for which no conventional diagnosis has been found OR with non-life threatening diagnoses not well-addressed by conventional medicinePeople with serious medical conditions: heart disease, cancer (stage 3-4),  diabetes, auto-immune disease, etc.
Initial visit
Personal Health Report
Phone
Follow-Up		30 mins60 minsunlimitedunlimitedunlimited
Email
Follow-up		60 mins60 minsunlimitedunlimitedunlimited
Investment$2995*$5995*$9995**$13995**$20,995***
* Health and Wellness Review follow-ups must be completed within 45 days** This is a Six Month Program** This is a Six Month Program** This is a Six Month Program*** Can be paid in monthly installments / one year program

Please Note: Dr. Myatt will apply the cost of the Health and Wellness Review toward any of her more advanced care programs.

Most people spend more money maintaining their car than they do maintaining their health. Dr. Myatt’s patients recognize that an investment in their health is one of the best investments they can make. Without your health, all other things in life — family, friends, possessions, hopes, dreams and plans for the future cannot be enjoyed to their fullest. What is your health worth to you?

What is it worth to add 10, 20, or more active years to your life?
What is it worth to have a slim, fit figure?
What is it worth to avoid a fatal heart attack? A stroke?
What is it worth to put an advanced cancer into remission?
What is it worth to turn back the clock and be healthy and full of life again?

Health Optimization Programs with Dr. Myatt: Affordable.
Good Health: PRICELESS.

Book A Brief Consultation Here To Get Started

Learn More About Consulting With Dr. Myatt Including “The Ultimate House Call”!

References

1.) CIA World Factbook accessed 10-29-10. https://www.cia.gov/library/publications/the-world-factbook/rankorder/2102rank.html
2.) Flegal, KM, Carroll, MD, Ogden, CL, Curtin, LR. Prevalence and Trends in Obesity Among US Adults, 1999–2008. Journal of the American Medical Association. 2010; 235–241.

Turmeric 500mg 60 caps

Powerful Cancer-fighting Herb
that drug companies are rushing to imitate.

An ever-growing body of scientific evidence demonstrates that turmeric — the bright yellow spice herb used in East Indian cooking — has potent anti-cancer properties. According to Bharat Aggarwal, chief of cytokine research at the University of Texas M.D. Anderson Cancer Center, the research to date shows that turmeric’s anti-cancer “promise is enormous.” This evidence and opinion was reported at the recent Society for Integrative Oncology conference and is also posted on the American Cancer Society’s website (www.cancer.org).

Turmeric, and it’s primary active ingredient curcumin, is the main ingredient in curry and a member of the ginger family. In addition to it’s anti-cancer properties, turmeric is a potent antioxidant, anti-inflammatory and liver-protecting herb. Expect to see and read a lot more about this herb in the future, although Wellness Club members have known about the benefits of turmeric for over a decade!

Turmeric (Curcuma longa)
Antioxidant, Anti-inflammatory and Anti-Cancer Herb
TurmericTurmeric (also known as curcumin), the bright yellow root used for centuries as a cooking spice, is also a potent medicinal herb.

Turmeric is:
anti-inflammatory
antioxidant
liver-protective (on a par with milk thistle)
anti-tumorogenic (helps prevent and may even help reverse tumors)
and helps maintain normal blood viscosity.
What more could you ask for in a non-toxic, beautiful, fragrant herb?

Turmeric (Curcuma longa) This herb is a potent antioxidant and anti-inflammatory. An ever-growing body of evidence suggests that turmeric may both help prevent AND help reverse already-existing cancers.

Each High-Potency Capsule contains: 500 mg of turmeric, standardized to 95% curcuminoids. (475mg active curcuminoids).

Suggested dose 1 capsule, 2-3 times per day.

You can learn more about turmeric and find one of the most potent turmeric supplements available on The Wellness Club website by visiting Turmeric: Antioxidant, Anti-inflammatory and Anti-Cancer Herb.

References

1.) Curcumin inhibits the mammalian target of rapamycin-mediated signaling pathways in cancer cells. Beevers,Li,Liu,Huang. Int J Cancer. 2006 Mar 20
2.) Antitumor action of curcumin in human papillomavirus associated cells involves downregulation of viral oncogenes, prevention of NFkB and AP-1 translocation, and modulation of apoptosis. Divya CS, Pillai MR. Mol Carcinog. 2006 May;45(5):320-32.
3.) Curcumin mediates ceramide generation via the de novo pathway in colon cancer cells. Moussavi M, Assi K, Gomez-Munoz A, Salh B. Carcinogenesis. 2006 Feb 25; [Epub ahead of print]
4.) Overexpression of p65/RelA potentiates curcumin-induced apoptosis in HCT116 human colon cancer cells. Collett GP, Campbell FC. Carcinogenesis. 2006 Feb 23; [Epub ahead of print]
5.) Induction of G2/M arrest and inhibition of cyclooxygenase-2 activity by curcumin in human bladder cancer T24 cells. Park C, Kim GY, Kim GD, Choi BT, Park YM, Choi YH. Oncol Rep. 2006 May;15(5):1225-31.
6.) Molecular targets of dietary agents for prevention and therapy of cancer. Aggarwal BB, Shishodia S. Biochem Pharmacol. 2006 Feb 23; [Epub ahead of print]
7.) Inhibition of telomerase activity and induction of apoptosis by curcumin in K-562 cells. Chakraborty S, Ghosh U, Bhattacharyya NP, Bhattacharya RK, Roy M. Mutat Res. 2006 Jan 27; [Epub ahead of print]
8.) Curcumin differentially sensitizes malignant glioma cells to TRAIL/Apo2L-mediated apoptosis through activation of procaspases and release of cytochrome c from mitochondria. Gao X, Deeb D, Jiang H, Liu YB, Dulchavsky SA, Gautam SC. J Exp Ther Oncol. 2005;5(1):39-48.
9.) Multiple biological activities of curcumin: a short review. Maheshwari RK, Singh AK, Gaddipati J, Srimal RC. Life Sci. 2006 Mar 27;78(18):2081-7. Epub 2006 Jan 18.
10.) Curcumin, an atoxic antioxidant and natural NFkappaB, cyclooxygenase-2, lipooxygenase, and inducible nitric oxide synthase inhibitor: a shield against acute and chronic diseases. Bengmark S. JPEN J Parenter Enteral Nutr. 2006 Jan-Feb;30(1):45-51.
11.) Antiproliferation and apoptosis induced by curcumin in human ovarian cancer cells. Shi M, Cai Q, Yao L, Mao Y, Ming Y, Ouyang G. Cell Biol Int. 2006 Mar;30(3):221-6. Epub 2005 Dec 22.
12.) Synergistic inhibitory effects of curcumin and 5-fluorouracil on the growth of the human colon cancer cell line HT-29. Du B, Jiang L, Xia Q, Zhong L. Chemotherapy. 2006;52(1):23-8. Epub 2005 Dec 9.
13.) Curcumin induces human HT-29 colon adenocarcinoma cell apoptosis by activating p53 and regulating apoptosis-related protein expression. Song G, Mao YB, Cai QF, Yao LM, Ouyang GL, Bao SD. Braz J Med Biol Res. 2005 Dec;38(12):1791-8. Epub 2005 Nov 9.
14.) Inhibition of cellular proliferation and induction of apoptosis by curcumin in human malignant astrocytoma cell lines. Nagai S, Kurimoto M, Washiyama K, Hirashima Y, Kumanishi T, Endo S. J Neurooncol. 2005 Sep;74(2):105-11.
15.) Curcumin inhibits human colon cancer cell growth by suppressing gene expression of epidermal growth factor receptor through reducing the activity of the transcription factor Egr-1. Chen A, Xu J, Johnson AC. Oncogene. 2006 Jan 12;25(2):278-87.

Fertility Restore CoQ10 100mg (60 softgel caps)

CoQ10 (ubiquinone)

Super-Energizer and Potent Antioxidant

CoQ10 is a naturally-occurring antioxidant produced in the human body. It is vitally involved in energy production. CoQ10 functions as an “energizer” to mitochondria, the body’s energy producing units. Mitochondria, which produce energy the body’s “energy currency,” ATP, require CoQ10 to “spark” their production of energy units (ATP). Muscles, and the heart in particular, have high requirements for CoQ10.

CoQ10 is a potent antioxidant beneficial for:

  • Heart Disease (angina, arrhythmia, atherosclerosis, cardiomyopathy, heart failure, congestive heart failure, myocardial infarction (1-18)
  • High Blood Pressure (1,3,4,14, 53, 55)
  • Neurological disease (Alzheimer’s, Huntington’s, Parkinson’s) (19-37)
  • Immune deficiency and AIDS (40-45,52)
  • Periodontal disease (38-39)
  • Cancer (40, 44-49)
  • Chemotherapy side-effects (50-52)
  • Diabetes (53-56)
  • Muscular dystrophy (57-58)
  • fatigue / chronic fatigue / fibromyalgia (59-61)
  • migraine headache (62-63)
  • enhancing athletic performance (64-68)
  • male infertility (69-73)

CoQ10 is produced by the body, but age, nutrient deficiencies, disease and some medications can lower the body’s CoQ10 levels. Cholesterol-lowering drugs (statins) deplete CoQ10. (15,54,74-77)

Studies have shown that the oil-preserved form is up to 3 times better absorbed than other forms. (78-80)

Although many claims are currently made for a “new” form (ubiquinol) being “more absorbable” than ubiquinone, this has never been proven or well-studied. Learn more about this issue here:Ubiquinone (CoQ10) versus Ubiquinol: Which Is Better?

CoQ10 and it’s use in CHF (Congestive Heart Failure):

http://www.ncbi.nlm.nih.gov/pubmed/19966871
“… Coenzyme Q10 (CoQ10) is essential for electron transport within the mitochondria and hence for ATP generation and cellular energy production. We recently demonstrated that plasma levels of CoQ10 are an independent predictor of survival in a cohort of 236 patients with chronic heart failure (CHF) followed for a median of 2.69 years. This is consistent with previous studies which have shown myocardial CoQ10 depletion in CHF, and correlated with the severity of the underlying disorder. Several intervention studies have been undertaken with CoQ10 in CHF, including randomized controlled trials with mostly positive outcomes in relation to improvement in plasma levels of CoQ10. A meta-analysis showed that CoQ10 resulted in an improvement in ejection fraction of 3.7% (95%CI 1.59-5.77) and the mean increase in cardiac output was 0.28 L/minute (95%CI 0.03-0.53). In a subgroup analysis, studies with patients not taking ACE inhibitors found a 6.7% increase in ejection fraction. The ongoing Q-SYMBIO trial will address whether CoQ10 supplementation improves survival in CHF patients. CoQ10 depletion may also be a contributory factor for why statin intervention has not improved outcomes in CHF. There is an emerging evidence base in support of CoQ10 as an adjunctive therapy in CHF.”

http://faculty.washington.edu/ely/coenzq10.html
“…The majority of the clinical studies concerned the treatment of heart disease and were remarkably consistent in their conclusions: that treatment with CoQ10 significantly improved heart muscle function while producing no adverse effects or drug interactions. …”

Dr. Myatt’s Conclusion:
CoQ10 is beneficial for nearly every type of Heart Disease (angina, arrhythmia, atherosclerosis, cardiomyopathy, heart failure, congestive heart failure, myocardial infarction (1-18)

Suggested dose:

50-100 mg per day for health maintenance and anti-aging / longevity programs.

200 to 400 mg per day for heart problems, cancer, weight loss programs and other indications.

Studies performed by the National Institutes of Health (NIH) using Vitaline ™ brand CoQ10, have used 300-400 mg (or more under medical direction) per day.

Each Capsule contains:

50 or 100 mg capsules are Wellness Club brand oil-preserved CoQ10 in easy to swallow gel Caps with Vitamin E & Beta carotene as natural preservatives.

300 and 400mg tablets are Vitaline/Integrative Therapeutics chewable wafers, the exact formulas used in the NIH Parkinson’s trials.

Product # 134 Wellness Club CoQ10 (60 softgel Caps 50 mg) 35.95

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Product # 135 Wellness Club (60 softgel Caps 100 mg) 62.95

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Vitaline CoQ10

Vitaline brand CoQ10 is THE CoQ10 that has been the subject of NIH studies and a recent trial showing its potential value in Parkinson’s patients.

Co10 has been shown to be potentially helpful for:

  • neurological health
  • cardiovascular health
  • anti-aging and longevity

NOTE: Vitaline® brand CoQ10 is available under several different labels.
Integrative Therapeutics
is the “Doctors Only” label		 Enzymatic Therapy
is the “Health Food Store” label		 Vitaline under the “Vitaline Formulas” Label is the same product

THESE ARE ALL THE EXACT SAME PRODUCT That Is Used In The NIH Studies
All are made by Vitaline and given different labels.

Product # N313 Vitaline (60 chewable wafers 300 mg With Vitamin E)97.00

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Product # N334 Vitaline (60 chewable wafers 300 mg WITHOUT Vit. E)97.00

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Product # N314 Vitaline (90 chewable wafers 400 mg With Vitamin E)197.00

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Product # N335 Vitaline (90 chewable wafers 400 mg WITHOUT Vit. E)197.00

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Vitaline, Vitamin E, and Vitamin E safety:

Some people (including some doctors) have a mistaken fear of Vitamin E, believing that “too much is dangerous.”

We have been unable to find any evidence in medical or scientific literature of any danger from taking large doses of Vitamin E. The National Institutes for Health (NIH) a US government authority places the maximum daily intake of Vitamin E at 1500 IU for healthy adults.

High intake of Vitamin E intake does tend to “thin” the blood, affecting coagulation by inhibiting platelet aggregation. People using antigoagulants or who bleed too easily may wish to discuss the use of Vitamin E with theri doctor.It has also been reported that Vitamin E in high doses may block the action of Vitamin K which is known as “the clotting factor.”

According to the label information and the Enzymatic Therapy website:

Vitaline® CoQ10 – 300 mg WITH Vitamin E contains 300 IU Vitamin E per chewable tab.

Vitaline® CoQ10 – 400 mg WITH Vitamin E contains 200 IU Vitamin E per chewable tab.

In order to achieve the daily intake of Vitamin E that you or your health care provider wish you to have you can either use a different tablet strength, either 300 or 400 mg to achieve 1200mg per day or mix your intake between Vitaline WITH and Vitaline WITHOUT Vitamin E to achieve your preferred daily intake of Vitamin E.

Vitaline 400 mg WITHOUT Vitamin E (Cherry-Vanilla flavor)
Serving Size: 3 Chewable wafers Amount/Serving %DV
Calories 35
Calories from fat 15
Total fat 1.5 gm 2%**
Total Carbohydrate 5 gm 2%**
Sugars 5 gm *
Natural Coenzyme Q10 (trans-CoQ10) (ubiquinone 10) 1.2 gm *
This product does not contain

  • all colors used are from natural sources
  • artificial flavoring
  • corn
  • dairy products
  • gluten
  • ingredients of animal origin
  • preservatives
  • salt
  • soy
  • sucrose
  • wheat
  • yeast

Notes

If pregnant, nursing, or taking prescription drugs, consult your healthcare practitioner prior to use.

Manufactured by a Drug GMP audited facility.

**Based on 2000 calorie diet.

Other Ingredients

fructose, dextrose, beet juice color, silicon dioxide, natural flavors, hydrogenated vegetable oil, magnesium stearate, and malic acid.
Vitaline 400 mg WITH Vitamin E (Orange flavor)
Serving Size: 3 Chewable wafers Amount/Serving %DV
Calories 35
Calories from fat 15
Total fat 1.5 gm 2 %**
Total Carbohydrate 5 gm 2 %**
Sugars 5 gm *
Natural Coenzyme Q10 (trans-CoQ10) (ubiquinone 10) 1.2 gm *
Vitamin E (as dl-alpha tocopheryl acetate) 600 IU 2000 %
This product does not contain

  • all colors used are from natural sources
  • artificial flavoring
  • corn
  • dairy products
  • gluten
  • ingredients of animal origin
  • preservatives
  • salt
  • soy
  • sucrose
  • wheat
  • yeast

Notes

If pregnant, nursing, or taking prescription drugs, consult your healthcare practitioner prior to use.

Manufactured by a Drug GMP audited facility.

**Based on 2000 calorie diet.

Other Ingredients

dextrose, fructose, silicon dioxide, hydrogenated vegetable oil, natural flavor, citric acid, and magnesium stearate.
Vitaline 300 mg WITH Vitamin E (Maple Nut flavor)
Serving Size: 4 Chewable wafers Amount/Serving %DV
Calories 35
Calories from fat 10
Total fat 1.5 gm 2 %**
Total Carbohydrate 5 gm 2 %**
Sugars 5 gm *
Natural Coenzyme Q10 (trans-CoQ10) (ubiquinone 10) 1.2 gm *
Vitamin E (as dl-alpha tocopheryl acetate) 1200 IU 4000 %
This product does not contain

  • all colors used are from natural sources
  • artificial flavoring
  • corn
  • dairy products
  • gluten
  • ingredients of animal origin
  • preservatives
  • salt
  • soy
  • sucrose
  • wheat
  • yeast

Notes

If pregnant, nursing, or taking prescription drugs, consult your healthcare practitioner prior to use.

Manufactured by a Drug GMP audited facility.

**Based on 2000 calorie diet.

Other Ingredients

dextrose, fructose, silicon dioxide, hydrogenated vegetable oil (cottonseed), natural vanilla flavor, magnesium stearate, and natural maple nut flavor.
Vitaline 300 mg WITHOUT Vitamin E (Maple Nutflavor)
Serving Size: 4 Chewable wafers Amount/Serving %DV
Calories 35
Calories from fat 15
Total fat 1.5 gm 2%**
Total Carbohydrate 3 gm 2%**
Sugars 3 gm *
Natural Coenzyme Q10 (trans-CoQ10) (ubiquinone 10) 1.2 gm *
This product does not contain

  • all colors used are from natural sources
  • artificial flavoring
  • corn
  • dairy products
  • gluten
  • ingredients of animal origin
  • preservatives
  • salt
  • soy
  • sucrose
  • wheat
  • yeast

Notes

If pregnant, nursing, or taking prescription drugs, consult your healthcare practitioner prior to use.

Manufactured by a Drug GMP audited facility.

**Based on 2000 calorie diet.

Other Ingredients

dextrose, fructose, cellulose, hydrogenated vegetable oil, partially hydrogenated soybean oil, silicon dioxide, natural vanilla flavor, magnesium stearate, sodium caseinate (milk), and natural maple nut flavor.

References:

1.) Adarsh K, Kaur H, Mohan V. Coenzyme Q10 (CoQ10) in isolated diastolic heart failure in hypertrophic cardiomyopathy (HCM). Biofactors. 2008;32(1-4):145-9.
2.) Berman M, Erman A, Ben-Gal T, Dvir D, Georghiou GP, Stamler A, Vered Y, Vidne BA, Aravot D. Coenzyme Q10 in patients with end-stage heart failure awaiting cardiac transplantation: a randomized, placebo-controlled study. Clin Cardiol. 2004 May;27(5):295-9.
3.) Hodgson JM, Watts GF, Playford DA, Burke V, Croft KD. Coenzyme Q10 improves blood pressure and glycaemic control: a controlled trial in subjects with type 2 diabetes. Eur J Clin Nutr. 2002 Nov;56(11):1137-42.
4.) Kumar A, Kaur H, Devi P, Mohan V. Role of Coenzyme Q10 (CoQ10) in Cardiac disease, Hypertension and Meniere- like syndrome. Pharmacol Ther. 2009 Jul 25. [Epub ahead of print]
5.) Langsjoen PH, Folkers K, Lyson K, Muratsu K, Lyson T, Langsjoen P. Pronounced increase of survival of patients with cardiomyopathy when treated with coenzyme Q10 and conventional therapy. Int J Tissue React. 1990;12(3):163-8.
6.) Langsjoen PH, Folkers K, Lyson K, Muratsu K, Lyson T, Langsjoen P. Effective and safe therapy with coenzyme Q10 for cardiomyopathy. Klin Wochenschr. 1988 Jul 1;66(13):583-90.
7.) Langsjoen P, Langsjoen A, Willis R, and Folkers K. The Aging Heart: Reversal of Diastolic Dysfunction Through the Use of Oral CoQ10 in the Elderly. Anti-Aging Medical Therapeutics. Klatz RM and Goldman R (eds.). Health Quest Publications. 1997;113-120.
8.) Langsjoen PH, Langsjoen A, Willis R, Folkers K. Treatment of hypertrophic cardiomyopathy with coenzyme Q10. Mol Aspects Med. 1997;18(S):s145-s151.
9.) Langsjoen PH, Vadhanavikit S, Folkers K. Response of patients in classes III and IV of cardiomyopathy to therapy in a blind and crossover trial with coenzyme Q10. Proc Natl Acad Sci U S A. 1985 Jun;82(12):4240-4.
10.) Mabuchi H, Higashikata T, Kawashiri M, Katsuda S, Mizuno M, Nohara A, Inazu A, Koizumi J, Kobayashi J. Reduction of serum ubiquinol-10 and ubiquinone-10 levels by atorvastatin in hypercholesterolemic patients. Journal of Atheroscler Thromb. 2005;12(2):111-9.
11.) Molyneux SL, Florkowski CM, George PM, Pilbrow AP, Frampton CM, Lever M, Richards AM. Coenzyme Q10: an independent predictor of mortality in chronic heart failure. J Am Coll Cardiol. 2008 Oct 28;52(18):1435-41.
12.) Mortensen SA. Overview on coenzyme Q10 as adjunctive therapy in chronic heart failure. Rationale, design and end-points of “Q-symbio”–a multinational trial. Biofactors. 2003;18(1-4):79-89.
13.) Mortensen S.A., Vadhanavikit S., Muratsu K., Folkers K. (1990) Coenzyme Q10: Clinical benefits with biochemical correlates suggesting a scientific breakthrough in the management of chronic heart failure. In: Int. J. Tissue React., Vol. 12 (3), pp 155-162.
14.) Rosenfeldt F, Hilton D, Pepe S, Krum H. Systematic review of effect of coenzyme Q10 in physical exercise, hypertension, and heart failure. Biofactors. 2003;18(1-4):91-100.
15.) Silver MA, Langsjoen PH, Szabo S, Patil H, Zelinger A. Effect of atorvastatin on left ventricular diastolic function and ability of coenzyme Q10 to reverse that dysfunction. Am J Cardiol. 2004 Nov 15;94(10):1306-10.
16.) Singh RB; Wander GS et al Randomized, double-blind placebo-controlled trial of coenzyme Q10 in patients with acute myocardial infarction. Cardiovasc Drugs Ther, 12(4):347-53 1998 Sep.
17.) Singh RB; Wander GS et al Cardiovasc Drugs Ther, 12(4):347-53 1998 Sep.
18.) Weant KA, Smith KM. The role of coenzyme Q10 in heart failure. Ann Pharmacother. 2005;39(9):1522-6.
19.) Beal MF. Coenzyme Q10 as a possible treatment for neurodegenerative diseases. Free Radic Res. 2002 Apr;36(4):455-60.
20.) Fallon J, Matthews RT, Hyman BT, Beal MF. MPP+ produces progressive neuronal degeneration which is mediated by oxidative stress. Exp Neurol. 1997 Mar;144(1):193-8.
21.) Feigin A, Kieburtz K, Como P, Hickey C, Claude K, Abwender D, Zimmerman C, Steinberg K, Shoulson I. Assessment of coenzyme Q10 tolerability in Huntington’s disease. Mov Disord. 1996;11(3):321-323.
22.) Ferrante KL, Shefner J, Zhang H, et al. Tolerance of high-dose (3,000 mg/day) coenzyme Q10 in ALS. Neurology. 2005 Dec 13;65(11):1834-1836.
23.) Flint Beal M, Matthews RT, Tieleman A, Shults CW. Coenzyme Q10 attenuates the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) induced loss of striatal dopamine and dopaminergic axons in aged mice. Brain Res. 1998;783:109-114.
24.) Flint Beal M, Matthews RT. Coenzyme Q10 in the central nervous system and its potential usefulness in the treatment of neurodegenerative diseases. Mol Aspects Med. 1997;18(S);s169-s179.
25.) Flint Beal M, Henshaw DR, Jenkins BG, Rosen BR, Schulz JB. Coenzyme Q10 and nicotinamide block striatal lesions produced by the mitochondrial toxin malonate. Ann Neurol. 1994;36:882-888.
26.) Jenkins BG, Brouillet E, Chen YC, Storey E, Schulz JB, Kirschner P, Beal MF, Rosen BR. Non-invasive neurochemical analysis of focal excitotoxic lesions in models of neurodegenerative illness using spectroscopic imaging. J Cereb Blood Flow Metab. 1996 May;16(3):450-61.
27.) Koroshetz WJ, Jenkins BG, Rosen BR, Flint Beal M. Energy metabolism defects in Huntington’s disease and effects of coenzyme Q10. Ann Neurol. 1997;41:160-165.
28.) Matthews RT, Yang L, Brown S, Baik MF. Coenzyme Q10 administration increases brain mitochondrial concentration and exerts neuroprotective effects. Proc Natl Acad Sci USA. 1998;95:8892-8897.
29.) Schilling G, Coonfield ML, Ross CA, Borchelt DR. Coenzyme Q10 and remacemide hydrochloride ameliorate motor deficits in a Huntington’s disease transgenic mouse model. Neurosci Lett. 2001 Nov 27;315(3):149-53.
30.) Shults CW, Oakes D, Kieburtz K, et al. Effects of Coenzyme Q10 in Early Parkinson’s Disease. Arch Neurol. 2002:59:1541-1550.
31.) Schulz B, Matthews RT, Henshaw DR, Beal MF. Neuroprotective strategies for treatment of lesions produced by mitochondrial toxins: implications for neurodegenerative diseases. Neuroscience. 1996;71(4):1043-1048.
32.) Shults CW, Flint Beal M, Fontaine D, Nakano K, Haas RH. Absorption, tolerability, and effects on mitochondrial activity of oral coenzyme Q10 in parkinsonian patients. Neurology. 1998;50:793-795.
33.) Shults CW, Haas RH, Passov D, Beal MF. Coenzyme Q10 levels correlate with the activities of complexes I and II/III in mitochondria from parkinsonian and nonparkinsonian subjects. Ann Neurol. 1997 Aug;42(2):261-4.
34.) Schulz JB, Henshaw R, Matthews RT, Flint Beal M. Coenzyme Q10 and nicotinamide and a free radical spin trap protect against MPTP neurotoxicity. Exp Neurol. 1995;132:279-283.
35.) Shults CW, Flint Beal M, Song D, Fontaine D. Pilot trial of high dosages of coenzyme Q10 in patients with Parkinson’s disease. Exp Neurol. 2004 Aug;188(2):491-4.
36.) The Huntington Study Group. A Randomized, Placebo-Controlled Trial of Coenzyme Q10 and Remacemide in Huntington’s Disease. Neurology. 2001:57:397-404.
37.) Yang L, Calingasan NY, Wille EJ, Cormier K, Smith K, Ferrante RJ, Beal MF. Combination therapy with coenzyme Q10 and creatine produces additive neuroprotective effects in models of Parkinson’s and Huntington’s diseases. J Neurochem. 2009 Jun;109(5):1427-39.
38.) Hanioka T, Tanaka M, Ojima M, Shizukuishi S, Folkers K. Effect of topical application of coenzyme Q10 on adult periodontitis. Mol Aspects Med. 1994;15 Suppl:s241-8.
39.)Nakamura R, Littarru GP, Folkers K, Wilkinson EG. Study of CoQ10-enzymes in gingiva from patients with periodontal disease and evidence for a deficiency of coenzyme Q10. Proc Natl Acad Sci U S A. 1974 Apr;71(4):1456-60.
40.) Folkers K, Hanioka T, Xia LJ, McRee JT Jr, Langsjoen P. Coenzyme Q10 increases T4/T8 ratios of lymphocytes in ordinary subjects and relevance to patients having the AIDS related complex. Biochem Biophys Res Commun. 1991 Apr 30;176(2):786-91.
41.) Folkers K, Langsjoen P, Nara Y, Muratsu K, Komorowski J, Richardson PC, Smith TH. Biochemical deficiencies of coenzyme Q10 in HIV-infection and exploratory treatment. Biochem Biophys Res Commun. 1988 Jun 16;153(2):888-96.
42.) Folkers K, Wolaniuk A. Research on coenzyme Q10 in clinical medicine and in immunomodulation. Drugs Exp Clin Res. 1985;11(8):539-45.
43.) Ravaglia G, Forti P, Maioli F, Bastagli L, Facchini A, Mariani E, Savarino L, Sassi S, Cucinotta D, Lenaz G. Effect of micronutrient status on natural killer cell immune function in healthy free-living subjects aged >/=90 y. Am J Clin Nutr. 2000 Feb;71(2):590-8.
44.) Folkers K, Morita M, McRee J Jr. The activities of coenzyme Q10 and vitamin B6 for immune responses. Biochem Biophys Res Commun. 1993 May 28;193(1):88-92.
45.) Folkers K, Brown R, Judy WV, Morita M. Biochem Biophys Res Commun. 1993 Apr 15;192(1):241-5.Survival of cancer patients on therapy with coenzyme Q10.
46.) Judy WV. Nutritional intervention in cancer prevention and treatment. American College for Advancement in Medicine Spring Conference, Ft. Lauderdale, FL. May 3, 1998.
47.) Lockwood K, Moesgaard S, Folkers K. Partial and complete regression of breast cancer in patients in relation to dosage of coenzyme Q10. Biochem Biophys Res Commun 1994;199:1504–8.
47.) Lockwood K, Moesgaard S, Hanioka T, Folkers K. Apparent partial remission of breast cancer in ‘high risk’ patients supplemented with nutritional antioxidants, essential fatty acids and coenzyme Q10. Mol Aspects Med. 1994;15 Suppl:s231-40.
48.) Lockwood K, Moesgaard S, Yamamoto T, Folkers K. Progress on therapy of breast cancer with vitamin Q10 and the regression of metastases. Biochem Biophys Res Commun 1995;212:172–7.
49.) Perumal SS, Shanthi P, Sachdanandam P. Energy-modulating vitamins–a new combinatorial therapy prevents cancer cachexia in rat mammary carcinoma.Br J Nutr. 2005 Jun;93(6):901-9.
50.) Conklin KA. Coenzyme q10 for prevention of anthracycline-induced cardiotoxicity. Integr Cancer Ther. 2005 Jun;4(2):110-30.
51.) Domae N, Sawada H, Matsuyama E, Konishi T, Uchino H. Cardiomyopathy and other chronic toxic effects induced in rabbits by doxorubicin and possible prevention by coenzyme Q10. Cancer Treat Rep. 1981 Jan-Feb;65(1-2):79-91.
52.) Folkers K, Wolaniuk A. Research on coenzyme Q10 in clinical medicine and in immunomodulation. Drugs Exp Clin Res. 1985;11(8):539-45.
53.) Chew GT, Watts GF, Davis TM, Stuckey BG, Beilin LJ, Thompson PL, Burke V, Currie PJ. Hemodynamic effects of fenofibrate and coenzyme Q10 in type 2 diabetic subjects with left ventricular diastolic dysfunction. Diabetes Care. 2008 Aug;31(8):1502-9. Epub 2008 May 16.
54.) Hamilton SJ, Chew GT, Watts GF. Coenzyme Q10 improves endothelial dysfunction in statin-treated type 2 diabetic patients. Diabetes Care. 2009 May;32(5):810-2. Epub 2009 Feb 19.
55.) Hodgson JM, Watts GF, Playford DA, Burke V, Croft KD. Coenzyme Q10 improves blood pressure and glycaemic control: a controlled trial in subjects with type 2 diabetes. Eur J Clin Nutr. 2002 Nov;56(11):1137-42.
56.) Watts GF, Playford DA, Croft KD, Ward NC, Mori TA, Burke V. Coenzyme Q(10) improves endothelial dysfunction of the brachial artery in Type II diabetes mellitus. Diabetologia. 2002 Mar;45(3):420-6.
57.) Folkers K, Simonsen R.Two successful double-blind trials with coenzyme Q10 (vitamin Q10) on muscular dystrophies and neurogenic atrophies. Biochim Biophys Acta. 1995 May 24;1271(1):281-6.
58.) Folkers K, Wolaniuk J, Simonsen R, Morishita M, Vadhanavikit S.Biochemical rationale and the cardiac response of patients with muscle disease to therapy with coenzyme Q10. Proc Natl Acad Sci U S A. 1985 Jul;82(13):4513-6.
59.) Bentler SE, Hartz AJ, Kuhn EM. Prospective observational study of treatments for unexplained chronic fatigue. J Clin Psychiatry. 2005 May;66(5):625-32.
60.) Cordero MD, Moreno-Fernández AM, deMiguel M, Bonal P, Campa F, Jiménez-Jiménez LM, Ruiz-Losada A, Sánchez-Domínguez B, Sánchez Alcázar JA, Salviati L, Navas P. Coenzyme Q10 distribution in blood is altered in patients with fibromyalgia. Clin Biochem. 2009 May;42(7-8):732-5. Epub 2008 Dec 25.
61.) Lister RE. An open, pilot study to evaluate the potential benefits of coenzyme Q10 combined with Ginkgo biloba extract in fibromyalgia syndrome. J Int Med Res. 2002 Mar-Apr;30(2):195-9.
62.) Sándor PS, Di Clemente L, Coppola G, Saenger U, Fumal A, Magis D, Seidel L, Agosti RM, Schoenen J. Efficacy of coenzyme Q10 in migraine prophylaxis: a randomized controlled trial. Neurology. 2005 Feb 22;64(4):713-5.
63.) Rozen TD, Oshinsky ML, Gebeline CA, Bradley KC, Young WB, Shechter AL, Silberstein SD. Open label trial of coenzyme Q10 as a migraine preventive. Cephalalgia. 2002 Mar;22(2):137-41.
64.) Cohen B, Gold D. Mitochondrial cytopathy in adults: What we know so far. Cleveland Clinic J Medicine 2001, 68:7,625-642.
65.) Cooke M, Iosia M, Buford T, Shelmadine B, Hudson G, Kerksick C, Rasmussen C, Greenwood M, Leutholtz B, Willoughby D, Kreider R.Effects of acute and 14-day coenzyme Q10 supplementation on exercise performance in both trained and untrained individuals. J Int Soc Sports Nutr. 2008 Mar 4;5:8.
66.) Gökbel H, Gül I, Belviranl M, Okudan N. The Effects Of Coenzyme Q10 Supplementation on Performance During Repeated Bouts of Supramaximal Exercise in Sedentary Men. J Strength Cond Res. 2009 Jul 28. [Epub ahead of print]
67.) Kon M, Tanabe K, Akimoto T, Kimura F, Tanimura Y, Shimizu K, Okamoto T, Kono I. Reducing exercise-induced muscular injury in kendo athletes with supplementation of coenzyme Q10. Br J Nutr. 2008 Feb 20;1-7. 68.) Mizuno K, Tanaka M, Nozaki S, Mizuma H, Ataka S, Tahara T, Sugino T, Shirai T, Kajimoto Y, Kuratsune H, Kajimoto O, Watanabe Y. Antifatigue effects of coenzyme Q10 during physical fatigue. Nutrition. 2008 Feb 11.
69.) Balercia G, Buldreghini E, Vignini A, Tiano L, Paggi F, Amoroso S, Ricciardo-Lamonica G, Boscaro M, Lenzi A, Littarru G. Coenzyme Q10 treatment in infertile men with idiopathic asthenozoospermia: a placebo-controlled, double-blind randomized trial. Fertil Steril. 2009 May;91(5):1785-92. 70.) Balercia G, Mancini A, Paggi F, Tiano L, Pontecorvi A, Boscaro M, Lenzi A, Littarru GP. COENZYME Q10 AND MALE INFERTILITY. J Endocrinol Invest. 2009 May 21. [Epub ahead of print]
71.) Balercia G, Mosca F, Mantero F, Boscaro M, Mancini A, Ricciardo-Lamonica G, Littarru G. Coenzyme Q(10) supplementation in infertile men with idiopathic asthenozoospermia: an open, uncontrolled pilot study. Fertil Steril. 2004 Jan;81(1):93-8.
72.) Littarru GP, Tiano L. Bioenergetic and antioxidant properties of coenzyme Q10: recent developments. Mol Biotechnol. 2007 Sep;37(1):31-7.
73.) Mancini A, De Marinis L, Littarru GP, Balercia G. An update of Coenzyme Q10 implications in male infertility: biochemical and therapeutic aspects. Biofactors. 2005;25(1-4):165-74.
74.) Joy TR, Hegele RA. Narrative review: statin-related myopathy. Ann Intern Med. 2009 Jun 16;150(12):858-68.
75.) Langsjoen PH, Langsjoen AM. The clinical use of HMG CoA-reductase inhibitors and the associated depletion of coenzyme Q10. A review of animal and human publications. Biofactors. 2003;18(1-4):101-11.
76.) Langsjoen PH, Langsjoen JO, Langsjoen AM, Lucas LA. Treatment of statin adverse effects with supplemental Coenzyme Q10 and statin drug discontinuation. Biofactors. 2005;25(1-4):147-52.
77.) Caso G, Kelly P, McNurlan MA, Lawson WE. Effect of coenzyme q10 on myopathic symptoms in patients treated with statins. Am J Cardiol. 2007 May 15;99(10):1409-12. Epub 2007 Apr 3.
78.) Bhagavan HN, Chopra RK. Plasma coenzyme Q10 response to oral ingestion of coenzyme Q10 formulations. Mitochondrion. 2007 Jun;7 Suppl:S78-88. Epub 2007 Mar 27.
79.) Chopra RK, Goldman R, Sinatra ST, Bhagavan HN. Relative bioavailability of coenzyme Q10 formulations in human subjects. Int J Vitam Nutr Res 1998;68:109–13.
80.)Weiss M, Mortensen SA, Rassig MR, et al. Bioavailability of four oral coenzyme Q10 formulations in healthy volunteers. Molec Aspects Med 1994;15:273–80

 

Vitaline Co-Q10 300 mg 60 chewable wafers With Vit. E

CoQ10 (ubiquinone)

Super-Energizer and Potent Antioxidant

CoQ10 is a naturally-occurring antioxidant produced in the human body. It is vitally involved in energy production. CoQ10 functions as an “energizer” to mitochondria, the body’s energy producing units. Mitochondria, which produce energy the body’s “energy currency,” ATP, require CoQ10 to “spark” their production of energy units (ATP). Muscles, and the heart in particular, have high requirements for CoQ10.

CoQ10 is a potent antioxidant beneficial for:

  • Heart Disease (angina, arrhythmia, atherosclerosis, cardiomyopathy, heart failure, congestive heart failure, myocardial infarction (1-18)
  • High Blood Pressure (1,3,4,14, 53, 55)
  • Neurological disease (Alzheimer’s, Huntington’s, Parkinson’s) (19-37)
  • Immune deficiency and AIDS (40-45,52)
  • Periodontal disease (38-39)
  • Cancer (40, 44-49)
  • Chemotherapy side-effects (50-52)
  • Diabetes (53-56)
  • Muscular dystrophy (57-58)
  • fatigue / chronic fatigue / fibromyalgia (59-61)
  • migraine headache (62-63)
  • enhancing athletic performance (64-68)
  • male infertility (69-73)

CoQ10 is produced by the body, but age, nutrient deficiencies, disease and some medications can lower the body’s CoQ10 levels. Cholesterol-lowering drugs (statins) deplete CoQ10. (15,54,74-77)

Studies have shown that the oil-preserved form is up to 3 times better absorbed than other forms. (78-80)

Although many claims are currently made for a “new” form (ubiquinol) being “more absorbable” than ubiquinone, this has never been proven or well-studied. Learn more about this issue here:Ubiquinone (CoQ10) versus Ubiquinol: Which Is Better?

CoQ10 and it’s use in CHF (Congestive Heart Failure):

http://www.ncbi.nlm.nih.gov/pubmed/19966871
“… Coenzyme Q10 (CoQ10) is essential for electron transport within the mitochondria and hence for ATP generation and cellular energy production. We recently demonstrated that plasma levels of CoQ10 are an independent predictor of survival in a cohort of 236 patients with chronic heart failure (CHF) followed for a median of 2.69 years. This is consistent with previous studies which have shown myocardial CoQ10 depletion in CHF, and correlated with the severity of the underlying disorder. Several intervention studies have been undertaken with CoQ10 in CHF, including randomized controlled trials with mostly positive outcomes in relation to improvement in plasma levels of CoQ10. A meta-analysis showed that CoQ10 resulted in an improvement in ejection fraction of 3.7% (95%CI 1.59-5.77) and the mean increase in cardiac output was 0.28 L/minute (95%CI 0.03-0.53). In a subgroup analysis, studies with patients not taking ACE inhibitors found a 6.7% increase in ejection fraction. The ongoing Q-SYMBIO trial will address whether CoQ10 supplementation improves survival in CHF patients. CoQ10 depletion may also be a contributory factor for why statin intervention has not improved outcomes in CHF. There is an emerging evidence base in support of CoQ10 as an adjunctive therapy in CHF.”

http://faculty.washington.edu/ely/coenzq10.html
“…The majority of the clinical studies concerned the treatment of heart disease and were remarkably consistent in their conclusions: that treatment with CoQ10 significantly improved heart muscle function while producing no adverse effects or drug interactions. …”

Dr. Myatt’s Conclusion:
CoQ10 is beneficial for nearly every type of Heart Disease (angina, arrhythmia, atherosclerosis, cardiomyopathy, heart failure, congestive heart failure, myocardial infarction (1-18)

Suggested dose:

50-100 mg per day for health maintenance and anti-aging / longevity programs.

200 to 400 mg per day for heart problems, cancer, weight loss programs and other indications.

Studies performed by the National Institutes of Health (NIH) using Vitaline ™ brand CoQ10, have used 300-400 mg (or more under medical direction) per day.

Each Capsule contains:

50 or 100 mg capsules are Wellness Club brand oil-preserved CoQ10 in easy to swallow gel Caps with Vitamin E & Beta carotene as natural preservatives.

300 and 400mg tablets are Vitaline/Integrative Therapeutics chewable wafers, the exact formulas used in the NIH Parkinson’s trials.

 Vitaline CoQ10

Vitaline brand CoQ10 is THE CoQ10 that has been the subject of NIH studies and a recent trial showing its potential value in Parkinson’s patients.

Co10 has been shown to be potentially helpful for:

  • neurological health
  • cardiovascular health
  • anti-aging and longevity

NOTE: Vitaline® brand CoQ10 is available under several different labels.
Integrative Therapeutics
is the “Doctors Only” label		 Enzymatic Therapy
is the “Health Food Store” label		 Vitaline under the “Vitaline Formulas” Label is the same product

THESE ARE ALL THE EXACT SAME PRODUCT That Is Used In The NIH Studies
All are made by Vitaline and given different labels.

Product # N313 Vitaline (60 chewable wafers 300 mg With Vitamin E)97.00

Vitaline, Vitamin E, and Vitamin E safety:

Some people (including some doctors) have a mistaken fear of Vitamin E, believing that “too much is dangerous.”

We have been unable to find any evidence in medical or scientific literature of any danger from taking large doses of Vitamin E. The National Institutes for Health (NIH) a US government authority places the maximum daily intake of Vitamin E at 1500 IU for healthy adults.

High intake of Vitamin E intake does tend to “thin” the blood, affecting coagulation by inhibiting platelet aggregation. People using antigoagulants or who bleed too easily may wish to discuss the use of Vitamin E with theri doctor.It has also been reported that Vitamin E in high doses may block the action of Vitamin K which is known as “the clotting factor.”

According to the label information and the Enzymatic Therapy website:

Vitaline® CoQ10 – 300 mg WITH Vitamin E contains 300 IU Vitamin E per chewable tab.

Vitaline® CoQ10 – 400 mg WITH Vitamin E contains 200 IU Vitamin E per chewable tab.

In order to achieve the daily intake of Vitamin E that you or your health care provider wish you to have you can either use a different tablet strength, either 300 or 400 mg to achieve 1200mg per day or mix your intake between Vitaline WITH and Vitaline WITHOUT Vitamin E to achieve your preferred daily intake of Vitamin E.

Vitaline 300 mg WITH Vitamin E (Maple Nut flavor)
Serving Size: 4 Chewable wafers Amount/Serving %DV
Calories 35
Calories from fat 10
Total fat 1.5 gm 2 %**
Total Carbohydrate 5 gm 2 %**
Sugars 5 gm *
Natural Coenzyme Q10 (trans-CoQ10) (ubiquinone 10) 1.2 gm *
Vitamin E (as dl-alpha tocopheryl acetate) 1200 IU 4000 %
This product does not contain

  • all colors used are from natural sources
  • artificial flavoring
  • corn
  • dairy products
  • gluten
  • ingredients of animal origin
  • preservatives
  • salt
  • soy
  • sucrose
  • wheat
  • yeast

Notes

If pregnant, nursing, or taking prescription drugs, consult your healthcare practitioner prior to use.

Manufactured by a Drug GMP audited facility.

**Based on 2000 calorie diet.

Other Ingredients

dextrose, fructose, silicon dioxide, hydrogenated vegetable oil (cottonseed), natural vanilla flavor, magnesium stearate, and natural maple nut flavor.

References:

1.) Adarsh K, Kaur H, Mohan V. Coenzyme Q10 (CoQ10) in isolated diastolic heart failure in hypertrophic cardiomyopathy (HCM). Biofactors. 2008;32(1-4):145-9.
2.) Berman M, Erman A, Ben-Gal T, Dvir D, Georghiou GP, Stamler A, Vered Y, Vidne BA, Aravot D. Coenzyme Q10 in patients with end-stage heart failure awaiting cardiac transplantation: a randomized, placebo-controlled study. Clin Cardiol. 2004 May;27(5):295-9.
3.) Hodgson JM, Watts GF, Playford DA, Burke V, Croft KD. Coenzyme Q10 improves blood pressure and glycaemic control: a controlled trial in subjects with type 2 diabetes. Eur J Clin Nutr. 2002 Nov;56(11):1137-42.
4.) Kumar A, Kaur H, Devi P, Mohan V. Role of Coenzyme Q10 (CoQ10) in Cardiac disease, Hypertension and Meniere- like syndrome. Pharmacol Ther. 2009 Jul 25. [Epub ahead of print]
5.) Langsjoen PH, Folkers K, Lyson K, Muratsu K, Lyson T, Langsjoen P. Pronounced increase of survival of patients with cardiomyopathy when treated with coenzyme Q10 and conventional therapy. Int J Tissue React. 1990;12(3):163-8.
6.) Langsjoen PH, Folkers K, Lyson K, Muratsu K, Lyson T, Langsjoen P. Effective and safe therapy with coenzyme Q10 for cardiomyopathy. Klin Wochenschr. 1988 Jul 1;66(13):583-90.
7.) Langsjoen P, Langsjoen A, Willis R, and Folkers K. The Aging Heart: Reversal of Diastolic Dysfunction Through the Use of Oral CoQ10 in the Elderly. Anti-Aging Medical Therapeutics. Klatz RM and Goldman R (eds.). Health Quest Publications. 1997;113-120.
8.) Langsjoen PH, Langsjoen A, Willis R, Folkers K. Treatment of hypertrophic cardiomyopathy with coenzyme Q10. Mol Aspects Med. 1997;18(S):s145-s151.
9.) Langsjoen PH, Vadhanavikit S, Folkers K. Response of patients in classes III and IV of cardiomyopathy to therapy in a blind and crossover trial with coenzyme Q10. Proc Natl Acad Sci U S A. 1985 Jun;82(12):4240-4.
10.) Mabuchi H, Higashikata T, Kawashiri M, Katsuda S, Mizuno M, Nohara A, Inazu A, Koizumi J, Kobayashi J. Reduction of serum ubiquinol-10 and ubiquinone-10 levels by atorvastatin in hypercholesterolemic patients. Journal of Atheroscler Thromb. 2005;12(2):111-9.
11.) Molyneux SL, Florkowski CM, George PM, Pilbrow AP, Frampton CM, Lever M, Richards AM. Coenzyme Q10: an independent predictor of mortality in chronic heart failure. J Am Coll Cardiol. 2008 Oct 28;52(18):1435-41.
12.) Mortensen SA. Overview on coenzyme Q10 as adjunctive therapy in chronic heart failure. Rationale, design and end-points of “Q-symbio”–a multinational trial. Biofactors. 2003;18(1-4):79-89.
13.) Mortensen S.A., Vadhanavikit S., Muratsu K., Folkers K. (1990) Coenzyme Q10: Clinical benefits with biochemical correlates suggesting a scientific breakthrough in the management of chronic heart failure. In: Int. J. Tissue React., Vol. 12 (3), pp 155-162.
14.) Rosenfeldt F, Hilton D, Pepe S, Krum H. Systematic review of effect of coenzyme Q10 in physical exercise, hypertension, and heart failure. Biofactors. 2003;18(1-4):91-100.
15.) Silver MA, Langsjoen PH, Szabo S, Patil H, Zelinger A. Effect of atorvastatin on left ventricular diastolic function and ability of coenzyme Q10 to reverse that dysfunction. Am J Cardiol. 2004 Nov 15;94(10):1306-10.
16.) Singh RB; Wander GS et al Randomized, double-blind placebo-controlled trial of coenzyme Q10 in patients with acute myocardial infarction. Cardiovasc Drugs Ther, 12(4):347-53 1998 Sep.
17.) Singh RB; Wander GS et al Cardiovasc Drugs Ther, 12(4):347-53 1998 Sep.
18.) Weant KA, Smith KM. The role of coenzyme Q10 in heart failure. Ann Pharmacother. 2005;39(9):1522-6.
19.) Beal MF. Coenzyme Q10 as a possible treatment for neurodegenerative diseases. Free Radic Res. 2002 Apr;36(4):455-60.
20.) Fallon J, Matthews RT, Hyman BT, Beal MF. MPP+ produces progressive neuronal degeneration which is mediated by oxidative stress. Exp Neurol. 1997 Mar;144(1):193-8.
21.) Feigin A, Kieburtz K, Como P, Hickey C, Claude K, Abwender D, Zimmerman C, Steinberg K, Shoulson I. Assessment of coenzyme Q10 tolerability in Huntington’s disease. Mov Disord. 1996;11(3):321-323.
22.) Ferrante KL, Shefner J, Zhang H, et al. Tolerance of high-dose (3,000 mg/day) coenzyme Q10 in ALS. Neurology. 2005 Dec 13;65(11):1834-1836.
23.) Flint Beal M, Matthews RT, Tieleman A, Shults CW. Coenzyme Q10 attenuates the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) induced loss of striatal dopamine and dopaminergic axons in aged mice. Brain Res. 1998;783:109-114.
24.) Flint Beal M, Matthews RT. Coenzyme Q10 in the central nervous system and its potential usefulness in the treatment of neurodegenerative diseases. Mol Aspects Med. 1997;18(S);s169-s179.
25.) Flint Beal M, Henshaw DR, Jenkins BG, Rosen BR, Schulz JB. Coenzyme Q10 and nicotinamide block striatal lesions produced by the mitochondrial toxin malonate. Ann Neurol. 1994;36:882-888.
26.) Jenkins BG, Brouillet E, Chen YC, Storey E, Schulz JB, Kirschner P, Beal MF, Rosen BR. Non-invasive neurochemical analysis of focal excitotoxic lesions in models of neurodegenerative illness using spectroscopic imaging. J Cereb Blood Flow Metab. 1996 May;16(3):450-61.
27.) Koroshetz WJ, Jenkins BG, Rosen BR, Flint Beal M. Energy metabolism defects in Huntington’s disease and effects of coenzyme Q10. Ann Neurol. 1997;41:160-165.
28.) Matthews RT, Yang L, Brown S, Baik MF. Coenzyme Q10 administration increases brain mitochondrial concentration and exerts neuroprotective effects. Proc Natl Acad Sci USA. 1998;95:8892-8897.
29.) Schilling G, Coonfield ML, Ross CA, Borchelt DR. Coenzyme Q10 and remacemide hydrochloride ameliorate motor deficits in a Huntington’s disease transgenic mouse model. Neurosci Lett. 2001 Nov 27;315(3):149-53.
30.) Shults CW, Oakes D, Kieburtz K, et al. Effects of Coenzyme Q10 in Early Parkinson’s Disease. Arch Neurol. 2002:59:1541-1550.
31.) Schulz B, Matthews RT, Henshaw DR, Beal MF. Neuroprotective strategies for treatment of lesions produced by mitochondrial toxins: implications for neurodegenerative diseases. Neuroscience. 1996;71(4):1043-1048.
32.) Shults CW, Flint Beal M, Fontaine D, Nakano K, Haas RH. Absorption, tolerability, and effects on mitochondrial activity of oral coenzyme Q10 in parkinsonian patients. Neurology. 1998;50:793-795.
33.) Shults CW, Haas RH, Passov D, Beal MF. Coenzyme Q10 levels correlate with the activities of complexes I and II/III in mitochondria from parkinsonian and nonparkinsonian subjects. Ann Neurol. 1997 Aug;42(2):261-4.
34.) Schulz JB, Henshaw R, Matthews RT, Flint Beal M. Coenzyme Q10 and nicotinamide and a free radical spin trap protect against MPTP neurotoxicity. Exp Neurol. 1995;132:279-283.
35.) Shults CW, Flint Beal M, Song D, Fontaine D. Pilot trial of high dosages of coenzyme Q10 in patients with Parkinson’s disease. Exp Neurol. 2004 Aug;188(2):491-4.
36.) The Huntington Study Group. A Randomized, Placebo-Controlled Trial of Coenzyme Q10 and Remacemide in Huntington’s Disease. Neurology. 2001:57:397-404.
37.) Yang L, Calingasan NY, Wille EJ, Cormier K, Smith K, Ferrante RJ, Beal MF. Combination therapy with coenzyme Q10 and creatine produces additive neuroprotective effects in models of Parkinson’s and Huntington’s diseases. J Neurochem. 2009 Jun;109(5):1427-39.
38.) Hanioka T, Tanaka M, Ojima M, Shizukuishi S, Folkers K. Effect of topical application of coenzyme Q10 on adult periodontitis. Mol Aspects Med. 1994;15 Suppl:s241-8.
39.)Nakamura R, Littarru GP, Folkers K, Wilkinson EG. Study of CoQ10-enzymes in gingiva from patients with periodontal disease and evidence for a deficiency of coenzyme Q10. Proc Natl Acad Sci U S A. 1974 Apr;71(4):1456-60.
40.) Folkers K, Hanioka T, Xia LJ, McRee JT Jr, Langsjoen P. Coenzyme Q10 increases T4/T8 ratios of lymphocytes in ordinary subjects and relevance to patients having the AIDS related complex. Biochem Biophys Res Commun. 1991 Apr 30;176(2):786-91.
41.) Folkers K, Langsjoen P, Nara Y, Muratsu K, Komorowski J, Richardson PC, Smith TH. Biochemical deficiencies of coenzyme Q10 in HIV-infection and exploratory treatment. Biochem Biophys Res Commun. 1988 Jun 16;153(2):888-96.
42.) Folkers K, Wolaniuk A. Research on coenzyme Q10 in clinical medicine and in immunomodulation. Drugs Exp Clin Res. 1985;11(8):539-45.
43.) Ravaglia G, Forti P, Maioli F, Bastagli L, Facchini A, Mariani E, Savarino L, Sassi S, Cucinotta D, Lenaz G. Effect of micronutrient status on natural killer cell immune function in healthy free-living subjects aged >/=90 y. Am J Clin Nutr. 2000 Feb;71(2):590-8.
44.) Folkers K, Morita M, McRee J Jr. The activities of coenzyme Q10 and vitamin B6 for immune responses. Biochem Biophys Res Commun. 1993 May 28;193(1):88-92.
45.) Folkers K, Brown R, Judy WV, Morita M. Biochem Biophys Res Commun. 1993 Apr 15;192(1):241-5.Survival of cancer patients on therapy with coenzyme Q10.
46.) Judy WV. Nutritional intervention in cancer prevention and treatment. American College for Advancement in Medicine Spring Conference, Ft. Lauderdale, FL. May 3, 1998.
47.) Lockwood K, Moesgaard S, Folkers K. Partial and complete regression of breast cancer in patients in relation to dosage of coenzyme Q10. Biochem Biophys Res Commun 1994;199:1504–8.
47.) Lockwood K, Moesgaard S, Hanioka T, Folkers K. Apparent partial remission of breast cancer in ‘high risk’ patients supplemented with nutritional antioxidants, essential fatty acids and coenzyme Q10. Mol Aspects Med. 1994;15 Suppl:s231-40.
48.) Lockwood K, Moesgaard S, Yamamoto T, Folkers K. Progress on therapy of breast cancer with vitamin Q10 and the regression of metastases. Biochem Biophys Res Commun 1995;212:172–7.
49.) Perumal SS, Shanthi P, Sachdanandam P. Energy-modulating vitamins–a new combinatorial therapy prevents cancer cachexia in rat mammary carcinoma.Br J Nutr. 2005 Jun;93(6):901-9.
50.) Conklin KA. Coenzyme q10 for prevention of anthracycline-induced cardiotoxicity. Integr Cancer Ther. 2005 Jun;4(2):110-30.
51.) Domae N, Sawada H, Matsuyama E, Konishi T, Uchino H. Cardiomyopathy and other chronic toxic effects induced in rabbits by doxorubicin and possible prevention by coenzyme Q10. Cancer Treat Rep. 1981 Jan-Feb;65(1-2):79-91.
52.) Folkers K, Wolaniuk A. Research on coenzyme Q10 in clinical medicine and in immunomodulation. Drugs Exp Clin Res. 1985;11(8):539-45.
53.) Chew GT, Watts GF, Davis TM, Stuckey BG, Beilin LJ, Thompson PL, Burke V, Currie PJ. Hemodynamic effects of fenofibrate and coenzyme Q10 in type 2 diabetic subjects with left ventricular diastolic dysfunction. Diabetes Care. 2008 Aug;31(8):1502-9. Epub 2008 May 16.
54.) Hamilton SJ, Chew GT, Watts GF. Coenzyme Q10 improves endothelial dysfunction in statin-treated type 2 diabetic patients. Diabetes Care. 2009 May;32(5):810-2. Epub 2009 Feb 19.
55.) Hodgson JM, Watts GF, Playford DA, Burke V, Croft KD. Coenzyme Q10 improves blood pressure and glycaemic control: a controlled trial in subjects with type 2 diabetes. Eur J Clin Nutr. 2002 Nov;56(11):1137-42.
56.) Watts GF, Playford DA, Croft KD, Ward NC, Mori TA, Burke V. Coenzyme Q(10) improves endothelial dysfunction of the brachial artery in Type II diabetes mellitus. Diabetologia. 2002 Mar;45(3):420-6.
57.) Folkers K, Simonsen R.Two successful double-blind trials with coenzyme Q10 (vitamin Q10) on muscular dystrophies and neurogenic atrophies. Biochim Biophys Acta. 1995 May 24;1271(1):281-6.
58.) Folkers K, Wolaniuk J, Simonsen R, Morishita M, Vadhanavikit S.Biochemical rationale and the cardiac response of patients with muscle disease to therapy with coenzyme Q10. Proc Natl Acad Sci U S A. 1985 Jul;82(13):4513-6.
59.) Bentler SE, Hartz AJ, Kuhn EM. Prospective observational study of treatments for unexplained chronic fatigue. J Clin Psychiatry. 2005 May;66(5):625-32.
60.) Cordero MD, Moreno-Fernández AM, deMiguel M, Bonal P, Campa F, Jiménez-Jiménez LM, Ruiz-Losada A, Sánchez-Domínguez B, Sánchez Alcázar JA, Salviati L, Navas P. Coenzyme Q10 distribution in blood is altered in patients with fibromyalgia. Clin Biochem. 2009 May;42(7-8):732-5. Epub 2008 Dec 25.
61.) Lister RE. An open, pilot study to evaluate the potential benefits of coenzyme Q10 combined with Ginkgo biloba extract in fibromyalgia syndrome. J Int Med Res. 2002 Mar-Apr;30(2):195-9.
62.) Sándor PS, Di Clemente L, Coppola G, Saenger U, Fumal A, Magis D, Seidel L, Agosti RM, Schoenen J. Efficacy of coenzyme Q10 in migraine prophylaxis: a randomized controlled trial. Neurology. 2005 Feb 22;64(4):713-5.
63.) Rozen TD, Oshinsky ML, Gebeline CA, Bradley KC, Young WB, Shechter AL, Silberstein SD. Open label trial of coenzyme Q10 as a migraine preventive. Cephalalgia. 2002 Mar;22(2):137-41.
64.) Cohen B, Gold D. Mitochondrial cytopathy in adults: What we know so far. Cleveland Clinic J Medicine 2001, 68:7,625-642.
65.) Cooke M, Iosia M, Buford T, Shelmadine B, Hudson G, Kerksick C, Rasmussen C, Greenwood M, Leutholtz B, Willoughby D, Kreider R.Effects of acute and 14-day coenzyme Q10 supplementation on exercise performance in both trained and untrained individuals. J Int Soc Sports Nutr. 2008 Mar 4;5:8.
66.) Gökbel H, Gül I, Belviranl M, Okudan N. The Effects Of Coenzyme Q10 Supplementation on Performance During Repeated Bouts of Supramaximal Exercise in Sedentary Men. J Strength Cond Res. 2009 Jul 28. [Epub ahead of print]
67.) Kon M, Tanabe K, Akimoto T, Kimura F, Tanimura Y, Shimizu K, Okamoto T, Kono I. Reducing exercise-induced muscular injury in kendo athletes with supplementation of coenzyme Q10. Br J Nutr. 2008 Feb 20;1-7. 68.) Mizuno K, Tanaka M, Nozaki S, Mizuma H, Ataka S, Tahara T, Sugino T, Shirai T, Kajimoto Y, Kuratsune H, Kajimoto O, Watanabe Y. Antifatigue effects of coenzyme Q10 during physical fatigue. Nutrition. 2008 Feb 11.
69.) Balercia G, Buldreghini E, Vignini A, Tiano L, Paggi F, Amoroso S, Ricciardo-Lamonica G, Boscaro M, Lenzi A, Littarru G. Coenzyme Q10 treatment in infertile men with idiopathic asthenozoospermia: a placebo-controlled, double-blind randomized trial. Fertil Steril. 2009 May;91(5):1785-92. 70.) Balercia G, Mancini A, Paggi F, Tiano L, Pontecorvi A, Boscaro M, Lenzi A, Littarru GP. COENZYME Q10 AND MALE INFERTILITY. J Endocrinol Invest. 2009 May 21. [Epub ahead of print]
71.) Balercia G, Mosca F, Mantero F, Boscaro M, Mancini A, Ricciardo-Lamonica G, Littarru G. Coenzyme Q(10) supplementation in infertile men with idiopathic asthenozoospermia: an open, uncontrolled pilot study. Fertil Steril. 2004 Jan;81(1):93-8.
72.) Littarru GP, Tiano L. Bioenergetic and antioxidant properties of coenzyme Q10: recent developments. Mol Biotechnol. 2007 Sep;37(1):31-7.
73.) Mancini A, De Marinis L, Littarru GP, Balercia G. An update of Coenzyme Q10 implications in male infertility: biochemical and therapeutic aspects. Biofactors. 2005;25(1-4):165-74.
74.) Joy TR, Hegele RA. Narrative review: statin-related myopathy. Ann Intern Med. 2009 Jun 16;150(12):858-68.
75.) Langsjoen PH, Langsjoen AM. The clinical use of HMG CoA-reductase inhibitors and the associated depletion of coenzyme Q10. A review of animal and human publications. Biofactors. 2003;18(1-4):101-11.
76.) Langsjoen PH, Langsjoen JO, Langsjoen AM, Lucas LA. Treatment of statin adverse effects with supplemental Coenzyme Q10 and statin drug discontinuation. Biofactors. 2005;25(1-4):147-52.
77.) Caso G, Kelly P, McNurlan MA, Lawson WE. Effect of coenzyme q10 on myopathic symptoms in patients treated with statins. Am J Cardiol. 2007 May 15;99(10):1409-12. Epub 2007 Apr 3.
78.) Bhagavan HN, Chopra RK. Plasma coenzyme Q10 response to oral ingestion of coenzyme Q10 formulations. Mitochondrion. 2007 Jun;7 Suppl:S78-88. Epub 2007 Mar 27.
79.) Chopra RK, Goldman R, Sinatra ST, Bhagavan HN. Relative bioavailability of coenzyme Q10 formulations in human subjects. Int J Vitam Nutr Res 1998;68:109–13.
80.)Weiss M, Mortensen SA, Rassig MR, et al. Bioavailability of four oral coenzyme Q10 formulations in healthy volunteers. Molec Aspects Med 1994;15:273–80.

 

 

Vitaline Co-Q10 400 mg 90 chewable wafers With Vit. E

CoQ10 (ubiquinone)

Super-Energizer and Potent Antioxidant

CoQ10 is a naturally-occurring antioxidant produced in the human body. It is vitally involved in energy production. CoQ10 functions as an “energizer” to mitochondria, the body’s energy producing units. Mitochondria, which produce energy the body’s “energy currency,” ATP, require CoQ10 to “spark” their production of energy units (ATP). Muscles, and the heart in particular, have high requirements for CoQ10.

CoQ10 is a potent antioxidant beneficial for:

  • Heart Disease (angina, arrhythmia, atherosclerosis, cardiomyopathy, heart failure, congestive heart failure, myocardial infarction (1-18)
  • High Blood Pressure (1,3,4,14, 53, 55)
  • Neurological disease (Alzheimer’s, Huntington’s, Parkinson’s) (19-37)
  • Immune deficiency and AIDS (40-45,52)
  • Periodontal disease (38-39)
  • Cancer (40, 44-49)
  • Chemotherapy side-effects (50-52)
  • Diabetes (53-56)
  • Muscular dystrophy (57-58)
  • fatigue / chronic fatigue / fibromyalgia (59-61)
  • migraine headache (62-63)
  • enhancing athletic performance (64-68)
  • male infertility (69-73)

CoQ10 is produced by the body, but age, nutrient deficiencies, disease and some medications can lower the body’s CoQ10 levels. Cholesterol-lowering drugs (statins) deplete CoQ10. (15,54,74-77)

Studies have shown that the oil-preserved form is up to 3 times better absorbed than other forms. (78-80)

Although many claims are currently made for a “new” form (ubiquinol) being “more absorbable” than ubiquinone, this has never been proven or well-studied. Learn more about this issue here:Ubiquinone (CoQ10) versus Ubiquinol: Which Is Better?

CoQ10 and it’s use in CHF (Congestive Heart Failure):

http://www.ncbi.nlm.nih.gov/pubmed/19966871
“… Coenzyme Q10 (CoQ10) is essential for electron transport within the mitochondria and hence for ATP generation and cellular energy production. We recently demonstrated that plasma levels of CoQ10 are an independent predictor of survival in a cohort of 236 patients with chronic heart failure (CHF) followed for a median of 2.69 years. This is consistent with previous studies which have shown myocardial CoQ10 depletion in CHF, and correlated with the severity of the underlying disorder. Several intervention studies have been undertaken with CoQ10 in CHF, including randomized controlled trials with mostly positive outcomes in relation to improvement in plasma levels of CoQ10. A meta-analysis showed that CoQ10 resulted in an improvement in ejection fraction of 3.7% (95%CI 1.59-5.77) and the mean increase in cardiac output was 0.28 L/minute (95%CI 0.03-0.53). In a subgroup analysis, studies with patients not taking ACE inhibitors found a 6.7% increase in ejection fraction. The ongoing Q-SYMBIO trial will address whether CoQ10 supplementation improves survival in CHF patients. CoQ10 depletion may also be a contributory factor for why statin intervention has not improved outcomes in CHF. There is an emerging evidence base in support of CoQ10 as an adjunctive therapy in CHF.”

http://faculty.washington.edu/ely/coenzq10.html
“…The majority of the clinical studies concerned the treatment of heart disease and were remarkably consistent in their conclusions: that treatment with CoQ10 significantly improved heart muscle function while producing no adverse effects or drug interactions. …”

Dr. Myatt’s Conclusion:
CoQ10 is beneficial for nearly every type of Heart Disease (angina, arrhythmia, atherosclerosis, cardiomyopathy, heart failure, congestive heart failure, myocardial infarction (1-18)

Suggested dose:

50-100 mg per day for health maintenance and anti-aging / longevity programs.

200 to 400 mg per day for heart problems, cancer, weight loss programs and other indications.

Studies performed by the National Institutes of Health (NIH) using Vitaline ™ brand CoQ10, have used 300-400 mg (or more under medical direction) per day.

Each Capsule contains:

50 or 100 mg capsules are Wellness Club brand oil-preserved CoQ10 in easy to swallow gel Caps with Vitamin E & Beta carotene as natural preservatives.

300 and 400mg tablets are Vitaline/Integrative Therapeutics chewable wafers, the exact formulas used in the NIH Parkinson’s trials.

Vitaline CoQ10

Vitaline brand CoQ10 is THE CoQ10 that has been the subject of NIH studies and a recent trial showing its potential value in Parkinson’s patients.

Co10 has been shown to be potentially helpful for:

  • neurological health
  • cardiovascular health
  • anti-aging and longevity

NOTE: Vitaline® brand CoQ10 is available under several different labels.
Vitaline CoQ10 Vitaline Vitaline Co-Enzyme Q10
Integrative Therapeutics
is the “Doctors Only” label		 Enzymatic Therapy
is the “Health Food Store” label		 Vitaline under the “Vitaline Formulas” Label is the same product

THESE ARE ALL THE EXACT SAME PRODUCT That Is Used In The NIH Studies
All are made by Vitaline and given different labels.

Product # N314 Vitaline (90 chewable wafers 400 mg With Vitamin E)197.00

 

Vitaline, Vitamin E, and Vitamin E safety:

Some people (including some doctors) have a mistaken fear of Vitamin E, believing that “too much is dangerous.”

We have been unable to find any evidence in medical or scientific literature of any danger from taking large doses of Vitamin E. The National Institutes for Health (NIH) a US government authority places the maximum daily intake of Vitamin E at 1500 IU for healthy adults.

High intake of Vitamin E intake does tend to “thin” the blood, affecting coagulation by inhibiting platelet aggregation. People using antigoagulants or who bleed too easily may wish to discuss the use of Vitamin E with theri doctor.It has also been reported that Vitamin E in high doses may block the action of Vitamin K which is known as “the clotting factor.”

According to the label information and the Enzymatic Therapy website:

Vitaline® CoQ10 – 300 mg WITH Vitamin E contains 300 IU Vitamin E per chewable tab.

Vitaline® CoQ10 – 400 mg WITH Vitamin E contains 200 IU Vitamin E per chewable tab.

In order to achieve the daily intake of Vitamin E that you or your health care provider wish you to have you can either use a different tablet strength, either 300 or 400 mg to achieve 1200mg per day or mix your intake between Vitaline WITH and Vitaline WITHOUT Vitamin E to achieve your preferred daily intake of Vitamin E.

Vitaline 400 mg WITH Vitamin E (Orange flavor)
Serving Size: 3 Chewable wafers Amount/Serving %DV
Calories 35
Calories from fat 15
Total fat 1.5 gm 2 %**
Total Carbohydrate 5 gm 2 %**
Sugars 5 gm *
Natural Coenzyme Q10 (trans-CoQ10) (ubiquinone 10) 1.2 gm *
Vitamin E (as dl-alpha tocopheryl acetate) 600 IU 2000 %
This product does not contain

  • all colors used are from natural sources
  • artificial flavoring
  • corn
  • dairy products
  • gluten
  • ingredients of animal origin
  • preservatives
  • salt
  • soy
  • sucrose
  • wheat
  • yeast

Notes

If pregnant, nursing, or taking prescription drugs, consult your healthcare practitioner prior to use.

Manufactured by a Drug GMP audited facility.

**Based on 2000 calorie diet.

Other Ingredients

dextrose, fructose, silicon dioxide, hydrogenated vegetable oil, natural flavor, citric acid, and magnesium stearate.

References:

1.) Adarsh K, Kaur H, Mohan V. Coenzyme Q10 (CoQ10) in isolated diastolic heart failure in hypertrophic cardiomyopathy (HCM). Biofactors. 2008;32(1-4):145-9.
2.) Berman M, Erman A, Ben-Gal T, Dvir D, Georghiou GP, Stamler A, Vered Y, Vidne BA, Aravot D. Coenzyme Q10 in patients with end-stage heart failure awaiting cardiac transplantation: a randomized, placebo-controlled study. Clin Cardiol. 2004 May;27(5):295-9.
3.) Hodgson JM, Watts GF, Playford DA, Burke V, Croft KD. Coenzyme Q10 improves blood pressure and glycaemic control: a controlled trial in subjects with type 2 diabetes. Eur J Clin Nutr. 2002 Nov;56(11):1137-42.
4.) Kumar A, Kaur H, Devi P, Mohan V. Role of Coenzyme Q10 (CoQ10) in Cardiac disease, Hypertension and Meniere- like syndrome. Pharmacol Ther. 2009 Jul 25. [Epub ahead of print]
5.) Langsjoen PH, Folkers K, Lyson K, Muratsu K, Lyson T, Langsjoen P. Pronounced increase of survival of patients with cardiomyopathy when treated with coenzyme Q10 and conventional therapy. Int J Tissue React. 1990;12(3):163-8.
6.) Langsjoen PH, Folkers K, Lyson K, Muratsu K, Lyson T, Langsjoen P. Effective and safe therapy with coenzyme Q10 for cardiomyopathy. Klin Wochenschr. 1988 Jul 1;66(13):583-90.
7.) Langsjoen P, Langsjoen A, Willis R, and Folkers K. The Aging Heart: Reversal of Diastolic Dysfunction Through the Use of Oral CoQ10 in the Elderly. Anti-Aging Medical Therapeutics. Klatz RM and Goldman R (eds.). Health Quest Publications. 1997;113-120.
8.) Langsjoen PH, Langsjoen A, Willis R, Folkers K. Treatment of hypertrophic cardiomyopathy with coenzyme Q10. Mol Aspects Med. 1997;18(S):s145-s151.
9.) Langsjoen PH, Vadhanavikit S, Folkers K. Response of patients in classes III and IV of cardiomyopathy to therapy in a blind and crossover trial with coenzyme Q10. Proc Natl Acad Sci U S A. 1985 Jun;82(12):4240-4.
10.) Mabuchi H, Higashikata T, Kawashiri M, Katsuda S, Mizuno M, Nohara A, Inazu A, Koizumi J, Kobayashi J. Reduction of serum ubiquinol-10 and ubiquinone-10 levels by atorvastatin in hypercholesterolemic patients. Journal of Atheroscler Thromb. 2005;12(2):111-9.
11.) Molyneux SL, Florkowski CM, George PM, Pilbrow AP, Frampton CM, Lever M, Richards AM. Coenzyme Q10: an independent predictor of mortality in chronic heart failure. J Am Coll Cardiol. 2008 Oct 28;52(18):1435-41.
12.) Mortensen SA. Overview on coenzyme Q10 as adjunctive therapy in chronic heart failure. Rationale, design and end-points of “Q-symbio”–a multinational trial. Biofactors. 2003;18(1-4):79-89.
13.) Mortensen S.A., Vadhanavikit S., Muratsu K., Folkers K. (1990) Coenzyme Q10: Clinical benefits with biochemical correlates suggesting a scientific breakthrough in the management of chronic heart failure. In: Int. J. Tissue React., Vol. 12 (3), pp 155-162.
14.) Rosenfeldt F, Hilton D, Pepe S, Krum H. Systematic review of effect of coenzyme Q10 in physical exercise, hypertension, and heart failure. Biofactors. 2003;18(1-4):91-100.
15.) Silver MA, Langsjoen PH, Szabo S, Patil H, Zelinger A. Effect of atorvastatin on left ventricular diastolic function and ability of coenzyme Q10 to reverse that dysfunction. Am J Cardiol. 2004 Nov 15;94(10):1306-10.
16.) Singh RB; Wander GS et al Randomized, double-blind placebo-controlled trial of coenzyme Q10 in patients with acute myocardial infarction. Cardiovasc Drugs Ther, 12(4):347-53 1998 Sep.
17.) Singh RB; Wander GS et al Cardiovasc Drugs Ther, 12(4):347-53 1998 Sep.
18.) Weant KA, Smith KM. The role of coenzyme Q10 in heart failure. Ann Pharmacother. 2005;39(9):1522-6.
19.) Beal MF. Coenzyme Q10 as a possible treatment for neurodegenerative diseases. Free Radic Res. 2002 Apr;36(4):455-60.
20.) Fallon J, Matthews RT, Hyman BT, Beal MF. MPP+ produces progressive neuronal degeneration which is mediated by oxidative stress. Exp Neurol. 1997 Mar;144(1):193-8.
21.) Feigin A, Kieburtz K, Como P, Hickey C, Claude K, Abwender D, Zimmerman C, Steinberg K, Shoulson I. Assessment of coenzyme Q10 tolerability in Huntington’s disease. Mov Disord. 1996;11(3):321-323.
22.) Ferrante KL, Shefner J, Zhang H, et al. Tolerance of high-dose (3,000 mg/day) coenzyme Q10 in ALS. Neurology. 2005 Dec 13;65(11):1834-1836.
23.) Flint Beal M, Matthews RT, Tieleman A, Shults CW. Coenzyme Q10 attenuates the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) induced loss of striatal dopamine and dopaminergic axons in aged mice. Brain Res. 1998;783:109-114.
24.) Flint Beal M, Matthews RT. Coenzyme Q10 in the central nervous system and its potential usefulness in the treatment of neurodegenerative diseases. Mol Aspects Med. 1997;18(S);s169-s179.
25.) Flint Beal M, Henshaw DR, Jenkins BG, Rosen BR, Schulz JB. Coenzyme Q10 and nicotinamide block striatal lesions produced by the mitochondrial toxin malonate. Ann Neurol. 1994;36:882-888.
26.) Jenkins BG, Brouillet E, Chen YC, Storey E, Schulz JB, Kirschner P, Beal MF, Rosen BR. Non-invasive neurochemical analysis of focal excitotoxic lesions in models of neurodegenerative illness using spectroscopic imaging. J Cereb Blood Flow Metab. 1996 May;16(3):450-61.
27.) Koroshetz WJ, Jenkins BG, Rosen BR, Flint Beal M. Energy metabolism defects in Huntington’s disease and effects of coenzyme Q10. Ann Neurol. 1997;41:160-165.
28.) Matthews RT, Yang L, Brown S, Baik MF. Coenzyme Q10 administration increases brain mitochondrial concentration and exerts neuroprotective effects. Proc Natl Acad Sci USA. 1998;95:8892-8897.
29.) Schilling G, Coonfield ML, Ross CA, Borchelt DR. Coenzyme Q10 and remacemide hydrochloride ameliorate motor deficits in a Huntington’s disease transgenic mouse model. Neurosci Lett. 2001 Nov 27;315(3):149-53.
30.) Shults CW, Oakes D, Kieburtz K, et al. Effects of Coenzyme Q10 in Early Parkinson’s Disease. Arch Neurol. 2002:59:1541-1550.
31.) Schulz B, Matthews RT, Henshaw DR, Beal MF. Neuroprotective strategies for treatment of lesions produced by mitochondrial toxins: implications for neurodegenerative diseases. Neuroscience. 1996;71(4):1043-1048.
32.) Shults CW, Flint Beal M, Fontaine D, Nakano K, Haas RH. Absorption, tolerability, and effects on mitochondrial activity of oral coenzyme Q10 in parkinsonian patients. Neurology. 1998;50:793-795.
33.) Shults CW, Haas RH, Passov D, Beal MF. Coenzyme Q10 levels correlate with the activities of complexes I and II/III in mitochondria from parkinsonian and nonparkinsonian subjects. Ann Neurol. 1997 Aug;42(2):261-4.
34.) Schulz JB, Henshaw R, Matthews RT, Flint Beal M. Coenzyme Q10 and nicotinamide and a free radical spin trap protect against MPTP neurotoxicity. Exp Neurol. 1995;132:279-283.
35.) Shults CW, Flint Beal M, Song D, Fontaine D. Pilot trial of high dosages of coenzyme Q10 in patients with Parkinson’s disease. Exp Neurol. 2004 Aug;188(2):491-4.
36.) The Huntington Study Group. A Randomized, Placebo-Controlled Trial of Coenzyme Q10 and Remacemide in Huntington’s Disease. Neurology. 2001:57:397-404.
37.) Yang L, Calingasan NY, Wille EJ, Cormier K, Smith K, Ferrante RJ, Beal MF. Combination therapy with coenzyme Q10 and creatine produces additive neuroprotective effects in models of Parkinson’s and Huntington’s diseases. J Neurochem. 2009 Jun;109(5):1427-39.
38.) Hanioka T, Tanaka M, Ojima M, Shizukuishi S, Folkers K. Effect of topical application of coenzyme Q10 on adult periodontitis. Mol Aspects Med. 1994;15 Suppl:s241-8.
39.)Nakamura R, Littarru GP, Folkers K, Wilkinson EG. Study of CoQ10-enzymes in gingiva from patients with periodontal disease and evidence for a deficiency of coenzyme Q10. Proc Natl Acad Sci U S A. 1974 Apr;71(4):1456-60.
40.) Folkers K, Hanioka T, Xia LJ, McRee JT Jr, Langsjoen P. Coenzyme Q10 increases T4/T8 ratios of lymphocytes in ordinary subjects and relevance to patients having the AIDS related complex. Biochem Biophys Res Commun. 1991 Apr 30;176(2):786-91.
41.) Folkers K, Langsjoen P, Nara Y, Muratsu K, Komorowski J, Richardson PC, Smith TH. Biochemical deficiencies of coenzyme Q10 in HIV-infection and exploratory treatment. Biochem Biophys Res Commun. 1988 Jun 16;153(2):888-96.
42.) Folkers K, Wolaniuk A. Research on coenzyme Q10 in clinical medicine and in immunomodulation. Drugs Exp Clin Res. 1985;11(8):539-45.
43.) Ravaglia G, Forti P, Maioli F, Bastagli L, Facchini A, Mariani E, Savarino L, Sassi S, Cucinotta D, Lenaz G. Effect of micronutrient status on natural killer cell immune function in healthy free-living subjects aged >/=90 y. Am J Clin Nutr. 2000 Feb;71(2):590-8.
44.) Folkers K, Morita M, McRee J Jr. The activities of coenzyme Q10 and vitamin B6 for immune responses. Biochem Biophys Res Commun. 1993 May 28;193(1):88-92.
45.) Folkers K, Brown R, Judy WV, Morita M. Biochem Biophys Res Commun. 1993 Apr 15;192(1):241-5.Survival of cancer patients on therapy with coenzyme Q10.
46.) Judy WV. Nutritional intervention in cancer prevention and treatment. American College for Advancement in Medicine Spring Conference, Ft. Lauderdale, FL. May 3, 1998.
47.) Lockwood K, Moesgaard S, Folkers K. Partial and complete regression of breast cancer in patients in relation to dosage of coenzyme Q10. Biochem Biophys Res Commun 1994;199:1504–8.
47.) Lockwood K, Moesgaard S, Hanioka T, Folkers K. Apparent partial remission of breast cancer in ‘high risk’ patients supplemented with nutritional antioxidants, essential fatty acids and coenzyme Q10. Mol Aspects Med. 1994;15 Suppl:s231-40.
48.) Lockwood K, Moesgaard S, Yamamoto T, Folkers K. Progress on therapy of breast cancer with vitamin Q10 and the regression of metastases. Biochem Biophys Res Commun 1995;212:172–7.
49.) Perumal SS, Shanthi P, Sachdanandam P. Energy-modulating vitamins–a new combinatorial therapy prevents cancer cachexia in rat mammary carcinoma.Br J Nutr. 2005 Jun;93(6):901-9.
50.) Conklin KA. Coenzyme q10 for prevention of anthracycline-induced cardiotoxicity. Integr Cancer Ther. 2005 Jun;4(2):110-30.
51.) Domae N, Sawada H, Matsuyama E, Konishi T, Uchino H. Cardiomyopathy and other chronic toxic effects induced in rabbits by doxorubicin and possible prevention by coenzyme Q10. Cancer Treat Rep. 1981 Jan-Feb;65(1-2):79-91.
52.) Folkers K, Wolaniuk A. Research on coenzyme Q10 in clinical medicine and in immunomodulation. Drugs Exp Clin Res. 1985;11(8):539-45.
53.) Chew GT, Watts GF, Davis TM, Stuckey BG, Beilin LJ, Thompson PL, Burke V, Currie PJ. Hemodynamic effects of fenofibrate and coenzyme Q10 in type 2 diabetic subjects with left ventricular diastolic dysfunction. Diabetes Care. 2008 Aug;31(8):1502-9. Epub 2008 May 16.
54.) Hamilton SJ, Chew GT, Watts GF. Coenzyme Q10 improves endothelial dysfunction in statin-treated type 2 diabetic patients. Diabetes Care. 2009 May;32(5):810-2. Epub 2009 Feb 19.
55.) Hodgson JM, Watts GF, Playford DA, Burke V, Croft KD. Coenzyme Q10 improves blood pressure and glycaemic control: a controlled trial in subjects with type 2 diabetes. Eur J Clin Nutr. 2002 Nov;56(11):1137-42.
56.) Watts GF, Playford DA, Croft KD, Ward NC, Mori TA, Burke V. Coenzyme Q(10) improves endothelial dysfunction of the brachial artery in Type II diabetes mellitus. Diabetologia. 2002 Mar;45(3):420-6.
57.) Folkers K, Simonsen R.Two successful double-blind trials with coenzyme Q10 (vitamin Q10) on muscular dystrophies and neurogenic atrophies. Biochim Biophys Acta. 1995 May 24;1271(1):281-6.
58.) Folkers K, Wolaniuk J, Simonsen R, Morishita M, Vadhanavikit S.Biochemical rationale and the cardiac response of patients with muscle disease to therapy with coenzyme Q10. Proc Natl Acad Sci U S A. 1985 Jul;82(13):4513-6.
59.) Bentler SE, Hartz AJ, Kuhn EM. Prospective observational study of treatments for unexplained chronic fatigue. J Clin Psychiatry. 2005 May;66(5):625-32.
60.) Cordero MD, Moreno-Fernández AM, deMiguel M, Bonal P, Campa F, Jiménez-Jiménez LM, Ruiz-Losada A, Sánchez-Domínguez B, Sánchez Alcázar JA, Salviati L, Navas P. Coenzyme Q10 distribution in blood is altered in patients with fibromyalgia. Clin Biochem. 2009 May;42(7-8):732-5. Epub 2008 Dec 25.
61.) Lister RE. An open, pilot study to evaluate the potential benefits of coenzyme Q10 combined with Ginkgo biloba extract in fibromyalgia syndrome. J Int Med Res. 2002 Mar-Apr;30(2):195-9.
62.) Sándor PS, Di Clemente L, Coppola G, Saenger U, Fumal A, Magis D, Seidel L, Agosti RM, Schoenen J. Efficacy of coenzyme Q10 in migraine prophylaxis: a randomized controlled trial. Neurology. 2005 Feb 22;64(4):713-5.
63.) Rozen TD, Oshinsky ML, Gebeline CA, Bradley KC, Young WB, Shechter AL, Silberstein SD. Open label trial of coenzyme Q10 as a migraine preventive. Cephalalgia. 2002 Mar;22(2):137-41.
64.) Cohen B, Gold D. Mitochondrial cytopathy in adults: What we know so far. Cleveland Clinic J Medicine 2001, 68:7,625-642.
65.) Cooke M, Iosia M, Buford T, Shelmadine B, Hudson G, Kerksick C, Rasmussen C, Greenwood M, Leutholtz B, Willoughby D, Kreider R.Effects of acute and 14-day coenzyme Q10 supplementation on exercise performance in both trained and untrained individuals. J Int Soc Sports Nutr. 2008 Mar 4;5:8.
66.) Gökbel H, Gül I, Belviranl M, Okudan N. The Effects Of Coenzyme Q10 Supplementation on Performance During Repeated Bouts of Supramaximal Exercise in Sedentary Men. J Strength Cond Res. 2009 Jul 28. [Epub ahead of print]
67.) Kon M, Tanabe K, Akimoto T, Kimura F, Tanimura Y, Shimizu K, Okamoto T, Kono I. Reducing exercise-induced muscular injury in kendo athletes with supplementation of coenzyme Q10. Br J Nutr. 2008 Feb 20;1-7. 68.) Mizuno K, Tanaka M, Nozaki S, Mizuma H, Ataka S, Tahara T, Sugino T, Shirai T, Kajimoto Y, Kuratsune H, Kajimoto O, Watanabe Y. Antifatigue effects of coenzyme Q10 during physical fatigue. Nutrition. 2008 Feb 11.
69.) Balercia G, Buldreghini E, Vignini A, Tiano L, Paggi F, Amoroso S, Ricciardo-Lamonica G, Boscaro M, Lenzi A, Littarru G. Coenzyme Q10 treatment in infertile men with idiopathic asthenozoospermia: a placebo-controlled, double-blind randomized trial. Fertil Steril. 2009 May;91(5):1785-92. 70.) Balercia G, Mancini A, Paggi F, Tiano L, Pontecorvi A, Boscaro M, Lenzi A, Littarru GP. COENZYME Q10 AND MALE INFERTILITY. J Endocrinol Invest. 2009 May 21. [Epub ahead of print]
71.) Balercia G, Mosca F, Mantero F, Boscaro M, Mancini A, Ricciardo-Lamonica G, Littarru G. Coenzyme Q(10) supplementation in infertile men with idiopathic asthenozoospermia: an open, uncontrolled pilot study. Fertil Steril. 2004 Jan;81(1):93-8.
72.) Littarru GP, Tiano L. Bioenergetic and antioxidant properties of coenzyme Q10: recent developments. Mol Biotechnol. 2007 Sep;37(1):31-7.
73.) Mancini A, De Marinis L, Littarru GP, Balercia G. An update of Coenzyme Q10 implications in male infertility: biochemical and therapeutic aspects. Biofactors. 2005;25(1-4):165-74.
74.) Joy TR, Hegele RA. Narrative review: statin-related myopathy. Ann Intern Med. 2009 Jun 16;150(12):858-68.
75.) Langsjoen PH, Langsjoen AM. The clinical use of HMG CoA-reductase inhibitors and the associated depletion of coenzyme Q10. A review of animal and human publications. Biofactors. 2003;18(1-4):101-11.
76.) Langsjoen PH, Langsjoen JO, Langsjoen AM, Lucas LA. Treatment of statin adverse effects with supplemental Coenzyme Q10 and statin drug discontinuation. Biofactors. 2005;25(1-4):147-52.
77.) Caso G, Kelly P, McNurlan MA, Lawson WE. Effect of coenzyme q10 on myopathic symptoms in patients treated with statins. Am J Cardiol. 2007 May 15;99(10):1409-12. Epub 2007 Apr 3.
78.) Bhagavan HN, Chopra RK. Plasma coenzyme Q10 response to oral ingestion of coenzyme Q10 formulations. Mitochondrion. 2007 Jun;7 Suppl:S78-88. Epub 2007 Mar 27.
79.) Chopra RK, Goldman R, Sinatra ST, Bhagavan HN. Relative bioavailability of coenzyme Q10 formulations in human subjects. Int J Vitam Nutr Res 1998;68:109–13.
80.)Weiss M, Mortensen SA, Rassig MR, et al. Bioavailability of four oral coenzyme Q10 formulations in healthy volunteers. Molec Aspects Med 1994;15:273–80.

 

 

Vitaline Co-Q10 300 mg 60 chewable wafers WITHOUT Vit.E

CoQ10 (ubiquinone)

Super-Energizer and Potent Antioxidant

CoQ10 is a naturally-occurring antioxidant produced in the human body. It is vitally involved in energy production. CoQ10 functions as an “energizer” to mitochondria, the body’s energy producing units. Mitochondria, which produce energy the body’s “energy currency,” ATP, require CoQ10 to “spark” their production of energy units (ATP). Muscles, and the heart in particular, have high requirements for CoQ10.

CoQ10 is a potent antioxidant beneficial for:

  • Heart Disease (angina, arrhythmia, atherosclerosis, cardiomyopathy, heart failure, congestive heart failure, myocardial infarction (1-18)
  • High Blood Pressure (1,3,4,14, 53, 55)
  • Neurological disease (Alzheimer’s, Huntington’s, Parkinson’s) (19-37)
  • Immune deficiency and AIDS (40-45,52)
  • Periodontal disease (38-39)
  • Cancer (40, 44-49)
  • Chemotherapy side-effects (50-52)
  • Diabetes (53-56)
  • Muscular dystrophy (57-58)
  • fatigue / chronic fatigue / fibromyalgia (59-61)
  • migraine headache (62-63)
  • enhancing athletic performance (64-68)
  • male infertility (69-73)

CoQ10 is produced by the body, but age, nutrient deficiencies, disease and some medications can lower the body’s CoQ10 levels. Cholesterol-lowering drugs (statins) deplete CoQ10. (15,54,74-77)

Studies have shown that the oil-preserved form is up to 3 times better absorbed than other forms. (78-80)

Although many claims are currently made for a “new” form (ubiquinol) being “more absorbable” than ubiquinone, this has never been proven or well-studied. Learn more about this issue here:Ubiquinone (CoQ10) versus Ubiquinol: Which Is Better?

CoQ10 and it’s use in CHF (Congestive Heart Failure):

http://www.ncbi.nlm.nih.gov/pubmed/19966871
“… Coenzyme Q10 (CoQ10) is essential for electron transport within the mitochondria and hence for ATP generation and cellular energy production. We recently demonstrated that plasma levels of CoQ10 are an independent predictor of survival in a cohort of 236 patients with chronic heart failure (CHF) followed for a median of 2.69 years. This is consistent with previous studies which have shown myocardial CoQ10 depletion in CHF, and correlated with the severity of the underlying disorder. Several intervention studies have been undertaken with CoQ10 in CHF, including randomized controlled trials with mostly positive outcomes in relation to improvement in plasma levels of CoQ10. A meta-analysis showed that CoQ10 resulted in an improvement in ejection fraction of 3.7% (95%CI 1.59-5.77) and the mean increase in cardiac output was 0.28 L/minute (95%CI 0.03-0.53). In a subgroup analysis, studies with patients not taking ACE inhibitors found a 6.7% increase in ejection fraction. The ongoing Q-SYMBIO trial will address whether CoQ10 supplementation improves survival in CHF patients. CoQ10 depletion may also be a contributory factor for why statin intervention has not improved outcomes in CHF. There is an emerging evidence base in support of CoQ10 as an adjunctive therapy in CHF.”

http://faculty.washington.edu/ely/coenzq10.html
“…The majority of the clinical studies concerned the treatment of heart disease and were remarkably consistent in their conclusions: that treatment with CoQ10 significantly improved heart muscle function while producing no adverse effects or drug interactions. …”

Dr. Myatt’s Conclusion:
CoQ10 is beneficial for nearly every type of Heart Disease (angina, arrhythmia, atherosclerosis, cardiomyopathy, heart failure, congestive heart failure, myocardial infarction (1-18)

Suggested dose:

50-100 mg per day for health maintenance and anti-aging / longevity programs.

200 to 400 mg per day for heart problems, cancer, weight loss programs and other indications.

Studies performed by the National Institutes of Health (NIH) using Vitaline ™ brand CoQ10, have used 300-400 mg (or more under medical direction) per day.

Each Capsule contains:

50 or 100 mg capsules are Wellness Club brand oil-preserved CoQ10 in easy to swallow gel Caps with Vitamin E & Beta carotene as natural preservatives.

300 and 400mg tablets are Vitaline/Integrative Therapeutics chewable wafers, the exact formulas used in the NIH Parkinson’s trials.Vitaline CoQ10

Vitaline brand CoQ10 is THE CoQ10 that has been the subject of NIH studies and a recent trial showing its potential value in Parkinson’s patients.

Co10 has been shown to be potentially helpful for:

  • neurological health
  • cardiovascular health
  • anti-aging and longevity

NOTE: Vitaline® brand CoQ10 is available under several different labels.
Integrative Therapeutics
is the “Doctors Only” label		 Enzymatic Therapy
is the “Health Food Store” label		 Vitaline under the “Vitaline Formulas” Label is the same product

THESE ARE ALL THE EXACT SAME PRODUCT That Is Used In The NIH Studies
All are made by Vitaline and given different labels.

Product # N334 Vitaline (60 chewable wafers 300 mg WITHOUT Vit. E)97.00

 

Vitaline, Vitamin E, and Vitamin E safety:

Some people (including some doctors) have a mistaken fear of Vitamin E, believing that “too much is dangerous.”

We have been unable to find any evidence in medical or scientific literature of any danger from taking large doses of Vitamin E. The National Institutes for Health (NIH) a US government authority places the maximum daily intake of Vitamin E at 1500 IU for healthy adults.

High intake of Vitamin E intake does tend to “thin” the blood, affecting coagulation by inhibiting platelet aggregation. People using antigoagulants or who bleed too easily may wish to discuss the use of Vitamin E with theri doctor.It has also been reported that Vitamin E in high doses may block the action of Vitamin K which is known as “the clotting factor.”

According to the label information and the Enzymatic Therapy website:

Vitaline® CoQ10 – 300 mg WITH Vitamin E contains 300 IU Vitamin E per chewable tab.

Vitaline® CoQ10 – 400 mg WITH Vitamin E contains 200 IU Vitamin E per chewable tab.

In order to achieve the daily intake of Vitamin E that you or your health care provider wish you to have you can either use a different tablet strength, either 300 or 400 mg to achieve 1200mg per day or mix your intake between Vitaline WITH and Vitaline WITHOUT Vitamin E to achieve your preferred daily intake of Vitamin E.

Vitaline 400 mg WITHOUT Vitamin E (Cherry-Vanilla flavor)
Serving Size: 3 Chewable wafers Amount/Serving %DV
Calories 35
Calories from fat 15
Total fat 1.5 gm 2%**
Total Carbohydrate 5 gm 2%**
Sugars 5 gm *
Natural Coenzyme Q10 (trans-CoQ10) (ubiquinone 10) 1.2 gm *
This product does not contain

  • all colors used are from natural sources
  • artificial flavoring
  • corn
  • dairy products
  • gluten
  • ingredients of animal origin
  • preservatives
  • salt
  • soy
  • sucrose
  • wheat
  • yeast

Notes

If pregnant, nursing, or taking prescription drugs, consult your healthcare practitioner prior to use.

Manufactured by a Drug GMP audited facility.

**Based on 2000 calorie diet.

Other Ingredients

fructose, dextrose, beet juice color, silicon dioxide, natural flavors, hydrogenated vegetable oil, magnesium stearate, and malic acid.

 

Vitaline Co-Q10 400 mg 90 chewable wafers WITHOUT Vit.E

CoQ10 (ubiquinone)

Super-Energizer and Potent Antioxidant

CoQ10 is a naturally-occurring antioxidant produced in the human body. It is vitally involved in energy production. CoQ10 functions as an “energizer” to mitochondria, the body’s energy producing units. Mitochondria, which produce energy the body’s “energy currency,” ATP, require CoQ10 to “spark” their production of energy units (ATP). Muscles, and the heart in particular, have high requirements for CoQ10.

CoQ10 is a potent antioxidant beneficial for:

  • Heart Disease (angina, arrhythmia, atherosclerosis, cardiomyopathy, heart failure, congestive heart failure, myocardial infarction (1-18)
  • High Blood Pressure (1,3,4,14, 53, 55)
  • Neurological disease (Alzheimer’s, Huntington’s, Parkinson’s) (19-37)
  • Immune deficiency and AIDS (40-45,52)
  • Periodontal disease (38-39)
  • Cancer (40, 44-49)
  • Chemotherapy side-effects (50-52)
  • Diabetes (53-56)
  • Muscular dystrophy (57-58)
  • fatigue / chronic fatigue / fibromyalgia (59-61)
  • migraine headache (62-63)
  • enhancing athletic performance (64-68)
  • male infertility (69-73)

CoQ10 is produced by the body, but age, nutrient deficiencies, disease and some medications can lower the body’s CoQ10 levels. Cholesterol-lowering drugs (statins) deplete CoQ10. (15,54,74-77)

Studies have shown that the oil-preserved form is up to 3 times better absorbed than other forms. (78-80)

Although many claims are currently made for a “new” form (ubiquinol) being “more absorbable” than ubiquinone, this has never been proven or well-studied. Learn more about this issue here:Ubiquinone (CoQ10) versus Ubiquinol: Which Is Better?

CoQ10 and it’s use in CHF (Congestive Heart Failure):

http://www.ncbi.nlm.nih.gov/pubmed/19966871
“… Coenzyme Q10 (CoQ10) is essential for electron transport within the mitochondria and hence for ATP generation and cellular energy production. We recently demonstrated that plasma levels of CoQ10 are an independent predictor of survival in a cohort of 236 patients with chronic heart failure (CHF) followed for a median of 2.69 years. This is consistent with previous studies which have shown myocardial CoQ10 depletion in CHF, and correlated with the severity of the underlying disorder. Several intervention studies have been undertaken with CoQ10 in CHF, including randomized controlled trials with mostly positive outcomes in relation to improvement in plasma levels of CoQ10. A meta-analysis showed that CoQ10 resulted in an improvement in ejection fraction of 3.7% (95%CI 1.59-5.77) and the mean increase in cardiac output was 0.28 L/minute (95%CI 0.03-0.53). In a subgroup analysis, studies with patients not taking ACE inhibitors found a 6.7% increase in ejection fraction. The ongoing Q-SYMBIO trial will address whether CoQ10 supplementation improves survival in CHF patients. CoQ10 depletion may also be a contributory factor for why statin intervention has not improved outcomes in CHF. There is an emerging evidence base in support of CoQ10 as an adjunctive therapy in CHF.”

http://faculty.washington.edu/ely/coenzq10.html
“…The majority of the clinical studies concerned the treatment of heart disease and were remarkably consistent in their conclusions: that treatment with CoQ10 significantly improved heart muscle function while producing no adverse effects or drug interactions. …”

Dr. Myatt’s Conclusion:
CoQ10 is beneficial for nearly every type of Heart Disease (angina, arrhythmia, atherosclerosis, cardiomyopathy, heart failure, congestive heart failure, myocardial infarction (1-18)

Suggested dose:

50-100 mg per day for health maintenance and anti-aging / longevity programs.

200 to 400 mg per day for heart problems, cancer, weight loss programs and other indications.

Studies performed by the National Institutes of Health (NIH) using Vitaline ™ brand CoQ10, have used 300-400 mg (or more under medical direction) per day.

Each Capsule contains:

50 or 100 mg capsules are Wellness Club brand oil-preserved CoQ10 in easy to swallow gel Caps with Vitamin E & Beta carotene as natural preservatives.

300 and 400mg tablets are Vitaline/Integrative Therapeutics chewable wafers, the exact formulas used in the NIH Parkinson’s trials.

Product # 134 Wellness Club CoQ10 (60 softgel Caps 50 mg) 35.95

Enter Quantity Desired and Click “Add To Cart” Button

 

Product # 135 Wellness Club (60 softgel Caps 100 mg) 62.95

Vitaline CoQ10

Vitaline brand CoQ10 is THE CoQ10 that has been the subject of NIH studies and a recent trial showing its potential value in Parkinson’s patients.

Co10 has been shown to be potentially helpful for:

  • neurological health
  • cardiovascular health
  • anti-aging and longevity

NOTE: Vitaline® brand CoQ10 is available under several different labels.
Integrative Therapeutics
is the “Doctors Only” label		 Enzymatic Therapy
is the “Health Food Store” label		 Vitaline under the “Vitaline Formulas” Label is the same product

THESE ARE ALL THE EXACT SAME PRODUCT That Is Used In The NIH Studies
All are made by Vitaline and given different labels.

Product # N314 Vitaline (90 chewable wafers 400 mg With Vitamin E)197.00

Product # N335 Vitaline (90 chewable wafers 400 mg WITHOUT Vit. E)197.00

Vitaline, Vitamin E, and Vitamin E safety:

Some people (including some doctors) have a mistaken fear of Vitamin E, believing that “too much is dangerous.”

We have been unable to find any evidence in medical or scientific literature of any danger from taking large doses of Vitamin E. The National Institutes for Health (NIH) a US government authority places the maximum daily intake of Vitamin E at 1500 IU for healthy adults.

High intake of Vitamin E intake does tend to “thin” the blood, affecting coagulation by inhibiting platelet aggregation. People using antigoagulants or who bleed too easily may wish to discuss the use of Vitamin E with theri doctor.It has also been reported that Vitamin E in high doses may block the action of Vitamin K which is known as “the clotting factor.”

According to the label information and the Enzymatic Therapy website:

Vitaline® CoQ10 – 400 mg WITH Vitamin E contains 200 IU Vitamin E per chewable tab.

In order to achieve the daily intake of Vitamin E that you or your health care provider wish you to have you can either use a different tablet strength, either 300 or 400 mg to achieve 1200mg per day or mix your intake between Vitaline WITH and Vitaline WITHOUT Vitamin E to achieve your preferred daily intake of Vitamin E.

Vitaline 400 mg WITHOUT Vitamin E (Cherry-Vanilla flavor)
Serving Size: 3 Chewable wafers Amount/Serving %DV
Calories 35
Calories from fat 15
Total fat 1.5 gm 2%**
Total Carbohydrate 5 gm 2%**
Sugars 5 gm *
Natural Coenzyme Q10 (trans-CoQ10) (ubiquinone 10) 1.2 gm *
This product does not contain

  • all colors used are from natural sources
  • artificial flavoring
  • corn
  • dairy products
  • gluten
  • ingredients of animal origin
  • preservatives
  • salt
  • soy
  • sucrose
  • wheat
  • yeast

Notes

If pregnant, nursing, or taking prescription drugs, consult your healthcare practitioner prior to use.

Manufactured by a Drug GMP audited facility.

**Based on 2000 calorie diet.

Other Ingredients

fructose, dextrose, beet juice color, silicon dioxide, natural flavors, hydrogenated vegetable oil, magnesium stearate, and malic acid.