Vitaline Co-Q10 300 mg 60 chewable wafers WITHOUT Vit.E

CoQ10 (ubiquinone)

Super-Energizer and Potent Antioxidant

CoQ10 is a naturally-occurring antioxidant produced in the human body. It is vitally involved in energy production. CoQ10 functions as an “energizer” to mitochondria, the body’s energy producing units. Mitochondria, which produce energy the body’s “energy currency,” ATP, require CoQ10 to “spark” their production of energy units (ATP). Muscles, and the heart in particular, have high requirements for CoQ10.

CoQ10 is a potent antioxidant beneficial for:

  • Heart Disease (angina, arrhythmia, atherosclerosis, cardiomyopathy, heart failure, congestive heart failure, myocardial infarction (1-18)
  • High Blood Pressure (1,3,4,14, 53, 55)
  • Neurological disease (Alzheimer’s, Huntington’s, Parkinson’s) (19-37)
  • Immune deficiency and AIDS (40-45,52)
  • Periodontal disease (38-39)
  • Cancer (40, 44-49)
  • Chemotherapy side-effects (50-52)
  • Diabetes (53-56)
  • Muscular dystrophy (57-58)
  • fatigue / chronic fatigue / fibromyalgia (59-61)
  • migraine headache (62-63)
  • enhancing athletic performance (64-68)
  • male infertility (69-73)

CoQ10 is produced by the body, but age, nutrient deficiencies, disease and some medications can lower the body’s CoQ10 levels. Cholesterol-lowering drugs (statins) deplete CoQ10. (15,54,74-77)

Studies have shown that the oil-preserved form is up to 3 times better absorbed than other forms. (78-80)

Although many claims are currently made for a “new” form (ubiquinol) being “more absorbable” than ubiquinone, this has never been proven or well-studied. Learn more about this issue here:Ubiquinone (CoQ10) versus Ubiquinol: Which Is Better?

CoQ10 and it’s use in CHF (Congestive Heart Failure):

http://www.ncbi.nlm.nih.gov/pubmed/19966871
“… Coenzyme Q10 (CoQ10) is essential for electron transport within the mitochondria and hence for ATP generation and cellular energy production. We recently demonstrated that plasma levels of CoQ10 are an independent predictor of survival in a cohort of 236 patients with chronic heart failure (CHF) followed for a median of 2.69 years. This is consistent with previous studies which have shown myocardial CoQ10 depletion in CHF, and correlated with the severity of the underlying disorder. Several intervention studies have been undertaken with CoQ10 in CHF, including randomized controlled trials with mostly positive outcomes in relation to improvement in plasma levels of CoQ10. A meta-analysis showed that CoQ10 resulted in an improvement in ejection fraction of 3.7% (95%CI 1.59-5.77) and the mean increase in cardiac output was 0.28 L/minute (95%CI 0.03-0.53). In a subgroup analysis, studies with patients not taking ACE inhibitors found a 6.7% increase in ejection fraction. The ongoing Q-SYMBIO trial will address whether CoQ10 supplementation improves survival in CHF patients. CoQ10 depletion may also be a contributory factor for why statin intervention has not improved outcomes in CHF. There is an emerging evidence base in support of CoQ10 as an adjunctive therapy in CHF.”

http://faculty.washington.edu/ely/coenzq10.html
“…The majority of the clinical studies concerned the treatment of heart disease and were remarkably consistent in their conclusions: that treatment with CoQ10 significantly improved heart muscle function while producing no adverse effects or drug interactions. …”

Dr. Myatt’s Conclusion:
CoQ10 is beneficial for nearly every type of Heart Disease (angina, arrhythmia, atherosclerosis, cardiomyopathy, heart failure, congestive heart failure, myocardial infarction (1-18)

Suggested dose:

50-100 mg per day for health maintenance and anti-aging / longevity programs.

200 to 400 mg per day for heart problems, cancer, weight loss programs and other indications.

Studies performed by the National Institutes of Health (NIH) using Vitaline ™ brand CoQ10, have used 300-400 mg (or more under medical direction) per day.

Each Capsule contains:

50 or 100 mg capsules are Wellness Club brand oil-preserved CoQ10 in easy to swallow gel Caps with Vitamin E & Beta carotene as natural preservatives.

300 and 400mg tablets are Vitaline/Integrative Therapeutics chewable wafers, the exact formulas used in the NIH Parkinson’s trials.Vitaline CoQ10

Vitaline brand CoQ10 is THE CoQ10 that has been the subject of NIH studies and a recent trial showing its potential value in Parkinson’s patients.

Co10 has been shown to be potentially helpful for:

  • neurological health
  • cardiovascular health
  • anti-aging and longevity

NOTE: Vitaline® brand CoQ10 is available under several different labels.

Integrative Therapeutics
is the “Doctors Only” label
Enzymatic Therapy
is the “Health Food Store” label
Vitaline under the “Vitaline Formulas” Label is the same product

THESE ARE ALL THE EXACT SAME PRODUCT That Is Used In The NIH Studies
All are made by Vitaline and given different labels.

Product # N334 Vitaline (60 chewable wafers 300 mg WITHOUT Vit. E)97.00

 

Vitaline, Vitamin E, and Vitamin E safety:

Some people (including some doctors) have a mistaken fear of Vitamin E, believing that “too much is dangerous.”

We have been unable to find any evidence in medical or scientific literature of any danger from taking large doses of Vitamin E. The National Institutes for Health (NIH) a US government authority places the maximum daily intake of Vitamin E at 1500 IU for healthy adults.

High intake of Vitamin E intake does tend to “thin” the blood, affecting coagulation by inhibiting platelet aggregation. People using antigoagulants or who bleed too easily may wish to discuss the use of Vitamin E with theri doctor.It has also been reported that Vitamin E in high doses may block the action of Vitamin K which is known as “the clotting factor.”

According to the label information and the Enzymatic Therapy website:

Vitaline® CoQ10 – 300 mg WITH Vitamin E contains 300 IU Vitamin E per chewable tab.

Vitaline® CoQ10 – 400 mg WITH Vitamin E contains 200 IU Vitamin E per chewable tab.

In order to achieve the daily intake of Vitamin E that you or your health care provider wish you to have you can either use a different tablet strength, either 300 or 400 mg to achieve 1200mg per day or mix your intake between Vitaline WITH and Vitaline WITHOUT Vitamin E to achieve your preferred daily intake of Vitamin E.


Vitaline 400 mg WITHOUT Vitamin E (Cherry-Vanilla flavor)
Serving Size: 3 Chewable wafers Amount/Serving %DV
Calories 35
Calories from fat 15
Total fat 1.5 gm 2%**
Total Carbohydrate 5 gm 2%**
Sugars 5 gm *
Natural Coenzyme Q10 (trans-CoQ10) (ubiquinone 10) 1.2 gm *
This product does not contain

  • all colors used are from natural sources
  • artificial flavoring
  • corn
  • dairy products
  • gluten
  • ingredients of animal origin
  • preservatives
  • salt
  • soy
  • sucrose
  • wheat
  • yeast

Notes

If pregnant, nursing, or taking prescription drugs, consult your healthcare practitioner prior to use.

Manufactured by a Drug GMP audited facility.

**Based on 2000 calorie diet.

Other Ingredients

fructose, dextrose, beet juice color, silicon dioxide, natural flavors, hydrogenated vegetable oil, magnesium stearate, and malic acid.

 

Vitaline Co-Q10 400 mg 90 chewable wafers WITHOUT Vit.E

CoQ10 (ubiquinone)

Super-Energizer and Potent Antioxidant

CoQ10 is a naturally-occurring antioxidant produced in the human body. It is vitally involved in energy production. CoQ10 functions as an “energizer” to mitochondria, the body’s energy producing units. Mitochondria, which produce energy the body’s “energy currency,” ATP, require CoQ10 to “spark” their production of energy units (ATP). Muscles, and the heart in particular, have high requirements for CoQ10.

CoQ10 is a potent antioxidant beneficial for:

  • Heart Disease (angina, arrhythmia, atherosclerosis, cardiomyopathy, heart failure, congestive heart failure, myocardial infarction (1-18)
  • High Blood Pressure (1,3,4,14, 53, 55)
  • Neurological disease (Alzheimer’s, Huntington’s, Parkinson’s) (19-37)
  • Immune deficiency and AIDS (40-45,52)
  • Periodontal disease (38-39)
  • Cancer (40, 44-49)
  • Chemotherapy side-effects (50-52)
  • Diabetes (53-56)
  • Muscular dystrophy (57-58)
  • fatigue / chronic fatigue / fibromyalgia (59-61)
  • migraine headache (62-63)
  • enhancing athletic performance (64-68)
  • male infertility (69-73)

CoQ10 is produced by the body, but age, nutrient deficiencies, disease and some medications can lower the body’s CoQ10 levels. Cholesterol-lowering drugs (statins) deplete CoQ10. (15,54,74-77)

Studies have shown that the oil-preserved form is up to 3 times better absorbed than other forms. (78-80)

Although many claims are currently made for a “new” form (ubiquinol) being “more absorbable” than ubiquinone, this has never been proven or well-studied. Learn more about this issue here:Ubiquinone (CoQ10) versus Ubiquinol: Which Is Better?

CoQ10 and it’s use in CHF (Congestive Heart Failure):

http://www.ncbi.nlm.nih.gov/pubmed/19966871
“… Coenzyme Q10 (CoQ10) is essential for electron transport within the mitochondria and hence for ATP generation and cellular energy production. We recently demonstrated that plasma levels of CoQ10 are an independent predictor of survival in a cohort of 236 patients with chronic heart failure (CHF) followed for a median of 2.69 years. This is consistent with previous studies which have shown myocardial CoQ10 depletion in CHF, and correlated with the severity of the underlying disorder. Several intervention studies have been undertaken with CoQ10 in CHF, including randomized controlled trials with mostly positive outcomes in relation to improvement in plasma levels of CoQ10. A meta-analysis showed that CoQ10 resulted in an improvement in ejection fraction of 3.7% (95%CI 1.59-5.77) and the mean increase in cardiac output was 0.28 L/minute (95%CI 0.03-0.53). In a subgroup analysis, studies with patients not taking ACE inhibitors found a 6.7% increase in ejection fraction. The ongoing Q-SYMBIO trial will address whether CoQ10 supplementation improves survival in CHF patients. CoQ10 depletion may also be a contributory factor for why statin intervention has not improved outcomes in CHF. There is an emerging evidence base in support of CoQ10 as an adjunctive therapy in CHF.”

http://faculty.washington.edu/ely/coenzq10.html
“…The majority of the clinical studies concerned the treatment of heart disease and were remarkably consistent in their conclusions: that treatment with CoQ10 significantly improved heart muscle function while producing no adverse effects or drug interactions. …”

Dr. Myatt’s Conclusion:
CoQ10 is beneficial for nearly every type of Heart Disease (angina, arrhythmia, atherosclerosis, cardiomyopathy, heart failure, congestive heart failure, myocardial infarction (1-18)

Suggested dose:

50-100 mg per day for health maintenance and anti-aging / longevity programs.

200 to 400 mg per day for heart problems, cancer, weight loss programs and other indications.

Studies performed by the National Institutes of Health (NIH) using Vitaline ™ brand CoQ10, have used 300-400 mg (or more under medical direction) per day.

Each Capsule contains:

50 or 100 mg capsules are Wellness Club brand oil-preserved CoQ10 in easy to swallow gel Caps with Vitamin E & Beta carotene as natural preservatives.

300 and 400mg tablets are Vitaline/Integrative Therapeutics chewable wafers, the exact formulas used in the NIH Parkinson’s trials.

Product # 134 Wellness Club CoQ10 (60 softgel Caps 50 mg) 35.95

Enter Quantity Desired and Click “Add To Cart” Button

 

Product # 135 Wellness Club (60 softgel Caps 100 mg) 62.95

Vitaline CoQ10

Vitaline brand CoQ10 is THE CoQ10 that has been the subject of NIH studies and a recent trial showing its potential value in Parkinson’s patients.

Co10 has been shown to be potentially helpful for:

  • neurological health
  • cardiovascular health
  • anti-aging and longevity

NOTE: Vitaline® brand CoQ10 is available under several different labels.

Integrative Therapeutics
is the “Doctors Only” label
Enzymatic Therapy
is the “Health Food Store” label
Vitaline under the “Vitaline Formulas” Label is the same product

THESE ARE ALL THE EXACT SAME PRODUCT That Is Used In The NIH Studies
All are made by Vitaline and given different labels.

Product # N314 Vitaline (90 chewable wafers 400 mg With Vitamin E)197.00

Product # N335 Vitaline (90 chewable wafers 400 mg WITHOUT Vit. E)197.00


Vitaline, Vitamin E, and Vitamin E safety:

Some people (including some doctors) have a mistaken fear of Vitamin E, believing that “too much is dangerous.”

We have been unable to find any evidence in medical or scientific literature of any danger from taking large doses of Vitamin E. The National Institutes for Health (NIH) a US government authority places the maximum daily intake of Vitamin E at 1500 IU for healthy adults.

High intake of Vitamin E intake does tend to “thin” the blood, affecting coagulation by inhibiting platelet aggregation. People using antigoagulants or who bleed too easily may wish to discuss the use of Vitamin E with theri doctor.It has also been reported that Vitamin E in high doses may block the action of Vitamin K which is known as “the clotting factor.”

According to the label information and the Enzymatic Therapy website:

Vitaline® CoQ10 – 400 mg WITH Vitamin E contains 200 IU Vitamin E per chewable tab.

In order to achieve the daily intake of Vitamin E that you or your health care provider wish you to have you can either use a different tablet strength, either 300 or 400 mg to achieve 1200mg per day or mix your intake between Vitaline WITH and Vitaline WITHOUT Vitamin E to achieve your preferred daily intake of Vitamin E.


Vitaline 400 mg WITHOUT Vitamin E (Cherry-Vanilla flavor)
Serving Size: 3 Chewable wafers Amount/Serving %DV
Calories 35
Calories from fat 15
Total fat 1.5 gm 2%**
Total Carbohydrate 5 gm 2%**
Sugars 5 gm *
Natural Coenzyme Q10 (trans-CoQ10) (ubiquinone 10) 1.2 gm *
This product does not contain

  • all colors used are from natural sources
  • artificial flavoring
  • corn
  • dairy products
  • gluten
  • ingredients of animal origin
  • preservatives
  • salt
  • soy
  • sucrose
  • wheat
  • yeast

Notes

If pregnant, nursing, or taking prescription drugs, consult your healthcare practitioner prior to use.

Manufactured by a Drug GMP audited facility.

**Based on 2000 calorie diet.

Other Ingredients

fructose, dextrose, beet juice color, silicon dioxide, natural flavors, hydrogenated vegetable oil, magnesium stearate, and malic acid.

 

Modified Citrus Pectin


Natural Anti-Metastatic Support

Modified Citrus Pectin (MCP) is derived from pectin, a high molecular-weight polysaccharide present in the cell wall of all plants. Pectin can be pH degraded to produce a modified (smaller) polysaccharide – modified citrus pectin – which has anti-metastatic properties. MCP appears to bind with galactans on cancer cell surfaces, inhibiting aggregation and adherence to normal cells and offering anti-metastatic protection in animal models.

Modified citrus pectin is readily absorbed in the GI tract and is completely non-toxic to humans. Although there are no good studies to verify MCP’s effectiveness in humans, animal studies repeatedly demonstrate MCP’s anti-metastatic capabilities. Because of the lack of toxicity of modified citrus pectin, and because conventional medicine has no drug or treatment to prevent metastasis, I recommend taking either MCP or larch in cases of cancer to help prevent or delay metastasis.

Dose: 2-3 teaspoons, 3 times daily. This may be added to your Super Shake or other beverage.

REFERENCES

1.) Guess BW, Scholz MC,Strum SB,LamRY, Johnson HJ, Jennrich RI. Modified citrus pectin (MCP) increases the prostate-specific antigen doubling time in men with prostate cancer: a phase II pilot study.Prostate Cancer and Prostatic Diseases (2003) 6, 301–304. doi:10.1038/sj.pcan.4500679
2.) Nangia-Makker P, Hogan V, Honjo Y, et al. Inhibition of human cancer cell growth and metastasis in nude mice by oral intake of modified citrus pectin. J Natl Cancer Inst. 2002;94:1854-1862.
3.) Strum S, Scholz M, McDermed J, et al. Modified citrus pectin slows PSA doubling time: A pilot clinical trial. Presentation: International Conference on Diet and Prevention of Cancer, Tampere, Finland. May 28, 1999 – June 2, 1999.
4.) Yan J, Katz AE. PectaSol-C Modified Citrus Pectin Induces Apoptosis and Inhibition of Proliferation in Human and Mouse Androgen-Dependent and Independent Prostate Cancer Cells. Integr Cancer Ther. 2010. http://www.ncbi.nlm.nih.gov/pubmed/20462856

Telephone Consultations with Dr. Myatt

Telephone Consultations
with Dr. Myatt

Get Fast Health Answers from a Natural Health Expert OR a Doctor-Designed Advanced Natural Health Program In the Comfort and convenience of Your Own Home

Would You Like to Turn the Clock Back 10 Years or More
And Have a Brand-New Lease on Life?

  • Brief Telephone Consultations (20 minutes)
  • General Health and Wellness Package
  • Health Recovery Program
  • Health Optimization Program (Anti-aging and Longevity)
  • Advanced Disease Rescue

What Natural Medicine Can Do for You — That Conventional Medicine Can’t

Modern conventional medicine performs amazing “heroic” care. If your broken body is found at the site of a serious car accident, conventional medicine’s ability to air-lift you to a hospital, CT scan you, set and pin broken bones, and keep you on life-support while you heal is what high-tech conventional medicine does best. And we are great at that — probably some of the best in the world.

But modern conventional U.S. medicine is NOT the best at everything. It it NOT the best solution for most day-to-day problems and most diseases. If it were, we would have some of the longest life expectancy — and health expectancy —- in the world. Yet here’s what the statistics show about health in the U.S.A.:

  • Americans spend 17+% of their GNP for health care, more than any other country in the world.
  • Life expectancy in America ranks 49th in the world, lagging far behind many countries who spend far less than we do for health (disease) care. (1)
  • Sixty-eight percent (two-thirds!) of Americans are overweight, thirty-three percent of these SEVERELY overweight (obese). (2)
  • Over ten million Americans take anti-depressants.
  • 50 percent of people over 85 will have Alzheimer’s Disease.
  • * Someone dies of heart disease every 34 seconds.
  • * One in six Americans suffers from an Anxiety Disorder.
  • * One in six Americans is either pre-diabetic or diabetic.

Modern medicine is an all but complete failure at curing or controlling chronic diseases such as cancer, heart disease, diabetes, obesity and anxiety/depression. Instead, the best conventional medicine can offer is a temporary “patch” for the major diseases of our time. In many instances, such as cancer treatment, the “medicine” often kills the patient before the disease would.

Beyond Conventional Drugs and Surgery — Natural Medicine Treats the Cause, Not Just the Symptom

Natural medicine and lifestyle counseling can prevent and reverse disease. This is because natural medicine looks for the cause of disease instead of merely treating symptoms. For example: depression has never been shown to be caused by a Prozac deficiency! But B complex vitamin deficiencies, lack of precursor amino acids (which are necessary to manufacture neurotransmitters), food allergies, heavy metal or other toxicities and emotional factors can all cause depression. Why mask a problem when the cause can be found and corrected? Genuine cure is more profound and certain than a Band-Aid will ever be.

Natural Medicine Treats the Patient, Not the Disease

No two people with the same disease have that disease for the exact same reason. Therefore, there can be no effective “one size fits all” medicine, yet this is how we are trained to treat people in the conventional medical model. For example: one person with irritable bowel syndrome is suffering because of a food allergy. Another may have the exact same diagnosis because of a lack of gastric acid function. A third may have IBS because of a yeast overgrowth in the colon. Yet the drugs prescribed for each of these patients is the same. Does this seem right to you?

Dr. Myatt Isn’t “Against” Drugs! (Especially Safe and Effective Ones)

Dr. Myatt practice complementary, integrative medicine, which means that she will use or recommend the best available treatment from both conventional and natural medicine. When  a drug or surgery seems like the best option, that is the advice she will give you.

If in her opinion you will benefit from a drug, that is what she will recommend and prescribe.

So often, however, our conventional drugs and treatments cause more harm than good. As a Naturopathic Medical Doctor, Dr. Myatt is trained to look for the cause of disease. Once the cause is known, there is opportunity for a genuine cure. The cure almost always entails natural methods, such as good nutrition, eliminating aggravating factors and restoring the body to a state of balance. These things are rarely if ever accomplished by drugs alone.

Dr. Myatt Finds “The Rest of The Story” that Modern Medicine Overlooks

If a person has a clear-cut set of symptoms, conventional medicine is good at giving the problem a name. We call this “diagnosis.” Just because we have named the problem does not imply that we know the cause, and in conventional medicine, it doesn’t even mean that we continue to look for a cause. You suffer from arthritis? There — we’ve got a name and we have a small collection of drugs that we will try until you feel pain relief. When your pain stops, our work is done. If none of our drugs stop your pain, oh well, we’ll just keep trying different drugs in different combinations.

The problem with this method of diagnosis and treatment is several-fold. First, because we are treating symptoms and not the cause, we might not be able to “cure” the problem with any of our available drugs. Secondly, since the treatment is a band-aid and doesn’t address the cause, the underlying problem is still going on with all the associated negative physical consequences. Finally, the drugs themselves usually have adverse consequences, up to and including death. Conventional treatment might offer some temporary pain relief, but at what cost?

Dr. Myatt looks for “the rest of the story.” If your diagnosis is arthritis, wouldn’t you like to know why your joints are deteriorating? The “wear and tear” theory has never been proven to be a cause of arthritis. Elderly marathon runners suffer far less arthritis than age-matched non-exercisers.

Is it a lack of bone and joint nutrients in the diet? An excess of inflammatory substances in the blood (which also increases heart disease and cancer risk)? A food allergy? Excess of a toxic substances or heavy metals? Once the underlying cause or causes are found, we not only have a better idea of how to stop pain, we have a genuine shot at a cure. And the side effects from natural remedies are that other complaints are often also corrected! Good things happen when we look for and treat the cause of a problem, not just the symptoms.

When No One Knows What’s Wrong

In conventional medicine, if your complaint fits into a neat little category that we can give a name to, we also know the drugs or surgeries that we are supposed to prescribe. They are in “the doctor cookbook.” But what if you have vague or unusual symptoms that don’t fit into any existing diagnosis?

If you have good insurance, you’ll get ATKTM — All Tests Known To Man (or all tests know to modern medicine). You may find yourself being CAT-scanned for an irritable bowel complaint and MRI’d for joint pains. Such ATKTM only rarely finds an anatomical cause for disease, and it NEVER locates a functional cause of disease.

Diagnostic tests are supposed to complement the doctor’s comprehensive evaluation, helping to “rule in” or “rule out” a suspected cause. Today, however, many physicians order tests in lieu of careful case study and patient evaluation. This “hit and miss” method of diagnosis is expensive, time-consuming and rarely productive. And when ATKTM comes back negative and you still have the complaint, then what? For conventional doctors it’s time to give you a “head med,” because if modern medical tests haven’t shown anything, the problem must be in your head.

The natural medical approach, which is Dr. Myatt’s approach, is to do a meticulous case study. By reviewing your symptoms, lab work, lifestyle and diet histories, family and personal medical histories, she is able to develop a solid “rule out” list of possible causes of your complaint.

Next, medical tests are ordered if they will rule in or out each of the items on the list. Like peeling the layers of an onion, she carefully explores the potential causes of your complaint until she finds it. In rare cases finding a cause is impossible, but most times it is merely difficult!

Using a combination of both conventional and alternative diagnostic measures, Dr. Myatt is able to find answers for many people who have been “given up on” by conventional medicine.

Why Dr. Myatt is The Doctor of First Resort — Prevention is Easier than Cure

Or stated differently, “If it ain’t broke, fix it before it breaks!”

Dr. Myatt and her team specialize in Health Optimization — making diet, lifestyle and other changes to prevent disease before it can establish a foot-hold.

Why wait until you have diabetes to make positive diet changes? Early signs, symptoms and lab abnormalities can predict your risk factors for many diseases years before they appear. The easiest time to correct a problem is before it even gets started. This is known as “preventive medicine,” and it is one of Dr. Myatt’s specialties. In the case of Health Optimization, a yearly review of your diet, symptoms, and lab results are recommended. From this, Dr. Myatt formulates a “Health Optimization Protocol” which is your personal guide to continued wellness for the coming year.

And Why She Is The Doctor of Last Resort — For “The Incurables” 

Prevention is always easier than cure, but perhaps you are past the point of prevention. If you already have a medical condition — even a serious one — Dr. Myatt can help. Her patients include people with advanced metastasized cancer, life-threatening heart conditions, autoimmune problems, neurological diseases and numerous other “incurable” problems.

With careful case-study and evaluation, Dr. Myatt makes health and life-saving recommendations to patients with all types of serious medical conditions.

Dr. Myatt’s patients have proven time and again that “where there’s life, there’s hope.”

Anti-Aging and Longevity Are Within Reach

Scientists estimate that the genetic lifespan of humans should be on the order of 120 years, yet the average US life expectancy for men and women is in the 70’s (and we rank 49th in the world for life expectancy).

For those who manage to live to 70’s 80’s and beyond, the way is often fraught with disease and disability for the last 20 or more years of life (the number of years of life spent in good health is known as “Health Span”). Why are we falling so short of our genetic potential for both lifespan and healthspan, in spite of the fact that we spend more on “health care” than any other nation on earth?

Modern medicine doesn’t really deliver “health care.” Instead, it is a model of “disease care,” waiting for a problem to happen  before taking action. Even then, the “action” taken is usually a Band-Aid instead of a cure. When it comes to prevention, health optimization and advanced methods of life extension, conventional medicine is woefully inadequate.

By identifying obstacles to good health and utilizing the vast body of longevity-enhancing techniques available, it is possible to extend both lifespan and healthspan. Much more is known about anti-aging and longevity than we currently utilize in conventional medicine.

Fortunately, alternative and complementary medical practices take advantage of this knowledge. Anti-aging and Longevity is one area of special interest and study for Dr. Myatt. She can help you know how to take advantage of your genetic potential for long life and good health.

You Can Consult Dr. Myatt In The Comfort of Your Home…. by Phone

Health Optimization requires careful medical detective work. Dr. Myatt evaluates your family history, personal past medical history, diet, lifestyle, risk factors, symptom profile and physiological stressors. She carefully reviews your laboratory reports and medical records, all pertinent medical data, and medications. Finally and most importantly, she listens carefully to your description of symptoms, complaints, and health goals. All of these factors are carefully weighed as Dr. Myatt and her medical team perform an exhaustive evaluation of your case.

Following your telephone consultation and case study by Dr. Myatt, you will receive your personalized Health Optimization Protocol. This report will include specific recommendations for diet, exercise, nutritional supplements, herbs and other conventional and/or complementary care — a complete “action plan” to put you on the path to Optimal Health, whether you are already healthy and looking to stay that way, or you suffer from a serious medical condition, or something in-between.

How Can Dr. Myatt Help Me Without Seeing Me in Person?

Dr. Myatt’s care does not replace your personal general physician. In fact, she insists that everyone have a personal family doctor in their local area. When the need arises, you should have someone locally who can listen to your lungs and heart with a stethoscope, perform routine examinations and stitch up boo-boos. Everyone needs a general family physician.

Dr. Myatt practices the advanced medical specialty of holistic and integrative medicine. Her evaluation of your case will go far beyond the type of medicine practiced conventionally. And because Dr. Myatt is also trained in conventional medicine, she can review and incorporate your conventional medical evaluations as part of your comprehensive work-up.

If you have asthma, for example, your local physician or health professional will have already listened to your lungs, referred your for breathing tests and prescribed medication. Dr. Myatt does not need to repeat this basic medical evaluation. She will, however, refer you to the appropriate type of medical practitioner when it appears that you have not had the complete “look” that should have been done. And she may suggest additional testing which has not been done by your conventional physician if it appears appropriate and necessary. This is all arranged by distance. Dr. Myatt writes prescriptions and lab orders for patients in every state and in countries around the world.

How Do I Enlist Dr. Myatt’s Services?

Use this link to schedule a brief telephone consultation. After you have completed purchase of your brief consultation, Dr. Myatt’s office will be in touch with you via email to schedule a time for this initial visit. Brief consultations can usually be scheduled quickly, usually within a matter of days.

All advanced patient programs begin with a brief telephone consultation. During this time, you will discuss your case with Dr. Myatt so that she can advise you as to which program / patient track is best suited to your unique situation.

If you elect to become a patient of Dr. Myatt’s after this initial visit, the cost of your brief phone consultation will be deducted from your program fees.

Next Steps: If You Are Accepted As a Patient

Before your initial one-hour intake visit, you will be asked to complete the following:

Patient information This form explains your relationship with Dr. Myatt, and how you will work together towards your best health ever.
Authorization to Release Medical RecordsThis form, signed and given to your other health care providers will allow them to send your medical records to Dr. Myatt for her study and analysis.
Patient Registration and Comprehensive IntakeThis form sounds simple, but here you will provide a great deal of information about yourself, your health, family history, medical history, diet, history of current illness and what you wish to achieve as you work together with Dr. Myatt.
Comprehensive Symptom SurveyThis 9 page health questionnaire and symptom survey will make you think hard. By completing it fully and honestly, you will provide Dr. Myatt with valuable insights to your body systems and clues to help her in her investigations as she develops your personalized Health Action Plan.

Copies of available medical records should be included (a records request form is included in case it is needed).

On the appointed day and time, Dr. Myatt will call you for your appointment. This initial “visit” is one hour long. Your Health Optimization Protocol will be mailed to you several days to a week later (to allow sufficient time for case study) and will contain a complete set of instructions and recommendations for everything needed to begin a healthier lifestyle.

Follow-Up and Ongoing Care

Everyone has different needs, hence the different levels of programs and services. A person with advanced heart disease or cancer will require much more contact and ongoing monitoring that a healthy person seeking to improve further on their good health. These factors are taken into account when Dr. Myatt advises which level of service your care requires.

Unless you are quite healthy and simply seeking expert advice on the best diet and nutritional supplement program, you will need to follow-up with Dr. Myatt via phone and internet (email) to insure proper execution of your program.

Adjustments and corrections may need to be made to your protocol, depending in large part on how you respond to treatment, your ability to follow the program as closely as possible, and other intervening factors. Dr. Myatt has taken the requisite follow-ups into account in the various levels of service she provides.

Your care will include follow-up and a “retainer”-based program for the email answers and other feedback you may need to keep you moving toward health at the fastest, most effective pace.

How Come Dr. Myatt Charges More Than Other Doctors?

She doesn’t. A specialist who sees you in-office for 15 minutes, for example, may charge $90. However, after you leave the office, this doctor spends no additional time reviewing your case.

Dr. Myatt will spend an initial hour discussing your health concerns, then she and her team go to work studying your case, including review of all relevant medical data. This “case study” typically takes from 4-12 hours depending on the nature and complexity of your health concerns. This often involves not just case study but also medical research on your behalf. Then and only then does Dr. Myatt create your “Recommendations,” a complete, written protocol for you to follow. When you consider the level of time, care and attention that each patient receives, Dr. Myatt’s fees are a bargain.

Why the “Retainer” and Pre-Paid Follow-Up Visits?

Dr. Myatt has found that the inclusive follow-ups and retainer program is in the best interest of her patients for the following reasons:

  1. Patients who have made a commitment are more likely to follow through. Follow-through produces positive results.
  2. Prevents “treatment failures.”  The initial recommendations are a solid “starting place” for good health, but the program must be adjusted and “tweaked” as circumstances change, new information becomes available and patient health improves.Some patients, after paying the initial consult fee, either drop out (fail to follow-through) because they don’t want to incur additional visit expenses OR because they expect unlimited email follow-up at no charge.By incorporating the predicted follow-up visits into program costs, patients are far more likely to follow-up. Making the necessary “course corrections” with Dr. Myatt’s careful guidance produces far better results than an initial visit with no follow-up.
  3. Get the answers you need — ALL of them. Your program fees include significant email follow-up. Got a question? No reason to stumble on your health program, get bad advice off the internet, or simply let a question go answered. All you have to do is email Dr. Myatt and she will respond with the information, assurance and guidance you need to keep you on track to a healthier life.
  4. Better cost predictions. How much will that “only $90” visit cost if you have to return to the doctor dozens of times over the same health concern? Costs for holistic care can add up to a big “unknown.” Although it is possible that a person may exceed their annual program allowance with Dr. Myatt, this is unusual. By having pre-paid for your care and follow-up, you can have a much better idea of what your advanced holistic care will cost.

Can Anyone Become a Patient? Why Does Dr. Myatt “Screen” New Patients?

Dr. Myatt is big on results, something even her advanced cancer patients will attest to.  Because of this, she is very particular about who she will accept as a patient. Only those who seem truly ready to put forth the necessary effort to get well, or improve health, are accepted.

And because each individual patient is given so much time and attention, Dr. Myatt must necessarily limit her services to only as many patients as she can truly devote herself to at any one time. When you are under Dr. Myatt’s care, you can rest assured that you are being watched over very carefully. She does not “spread herself thin” and accept more patients than she can be totally devoted to.

There are also some patients who have ideas and desires that would make them unsuited to Dr. Myatt’s method of practice.

For example, Dr. Myatt is a firm believer in scientific holistic medicine. She does not practice “esoteric” or unproven techniques although she is familiar with most of them. Patients who want “chakra balancing,” “aura cleansing” or recommendation of nutritional supplements by crystal pendulum dowsing would not be happy with Dr. Myatt’s highly scientific, well-researched and proven methods of practice.

How Dr. Myatt’s Health Optimization Program is Different from other Healthcare Practices

  • Dr. Myatt takes the time to listen. No “quickie” initial or follow-up visits. Dr. Myatt takes the time to truly listen to your symptoms, complaints, questions and health goals. She and her team also spend an extensive amount of time reviewing your individual case. Very few physicians — even holistic and naturopathic practitioners — spend so much time entirely devoted to each individual patient.
  • Dr. Myatt and Team perform an in-depth analysis for each patient. Our testing is typically more comprehensive than traditional laboratory testing. We use “optimal,” not just “normal” values for lab interpretation. We look beyond the bounds of conventional “disease diagnosis” and try to truly understand the underlying causes and imbalances contributing to an individual’s symptoms.
  • “Tolle causum” — treat the cause. We are totally devoted to discovering the “hidden causes” of your health challenges in a way that goes far beyond conventional medical diagnosis and treatment. From this, we develop a customized treatment plan exclusively for you. No two people, even with the same diagnosis, will have the same treatment plan because all of our work is highly individualized.
  • “Vis Medicatrix Naturae” — with the healing power of nature. The human body is, to a great extent, self-healing when given the proper conditions. We cooperate with nature by using TLC — Therapeutic Lifestyle Changes — and natural remedies to stimulate the body to heal itself.

Modalities that Dr. Myatt Uses to Treat Disease and Optimize Health

Dr. Myatt is trained and licensed in conventional medical treatment including convention laboratory and physical diagnosis of disease. She can write prescriptions for drugs, deliver babies, commit surgeries, and sign death certificates.

However, her primary methods of treatment — “Vis Medicatrix Naturae” — include:

  • Diet and nutrition / nutritional supplements
  • Botanical medicine
  • Exercise and fitness programs
  • Bio-identical hormone therapy
  • Detoxification programs
  • Immune Enhancement
  • Lifestyle Counseling

Dr. Myatt’s Specialties Include:

  • Anti-aging and Longevity Medicine
  • ADD / ADHD
  • Auto-immune Disease
  • Heart Disease Prevention and Reversal
  • Cancer Prevention and Treatment Options
  • Natural (bio-identical) Hormone Replacement Therapy
  • Diabetes Managements and Type II Diabetes CURE
  • Anxiety, Depression and other Mood Disorders
  • Adrenal and Thyroid Dysfunction
  • Weight Loss and Maintenance
  • Digestive Difficulties (IBS, constipation, diarrhea, GERD)
  • Osteopenia / Osteoporosis
  • Infertility
  • Health Optimization
  • “Real” — Carefully Researched And Considered — Second Opinions

What Level of Care Best Suits Your Needs?

Health and Wellness Review 1 *Health and Wellness Review 2 *Anti-aging / Health OptimizationHealth Recovery ProgramAdvanced Health Rescue
Who is this for?People with no diagnosed disease and minor or no health problems who want an holistic review of their diet, lifestyle, and recent medical (lab) reportsPeople with diagnosed disease and minor to moderate health problems who want an holistic review of their diet, lifestyle, and recent medical (lab) reportsHealthy people (no disease) who want to optimize their health further and implement an anti-aging programPeople with health problems for which no conventional diagnosis has been found OR with non-life threatening diagnoses not well-addressed by conventional medicinePeople with serious medical conditions: heart disease, cancer (stage 3-4),  diabetes, auto-immune disease, etc.
Initial visit
Personal Health Report
Phone
Follow-Up
30 mins60 minsunlimitedunlimitedunlimited
Email
Follow-up
60 mins60 minsunlimitedunlimitedunlimited
Investment$2995*$5995*$9995**$13995**$20,995***
* Health and Wellness Review follow-ups must be completed within 45 days** This is a Six Month Program** This is a Six Month Program** This is a Six Month Program*** Can be paid in monthly installments / one year program

Please Note: Dr. Myatt will apply the cost of the Health and Wellness Review toward any of her more advanced care programs.

Most people spend more money maintaining their car than they do maintaining their health. Dr. Myatt’s patients recognize that an investment in their health is one of the best investments they can make. Without your health, all other things in life — family, friends, possessions, hopes, dreams and plans for the future cannot be enjoyed to their fullest. What is your health worth to you?

What is it worth to add 10, 20, or more active years to your life?
What is it worth to have a slim, fit figure?
What is it worth to avoid a fatal heart attack? A stroke?
What is it worth to put an advanced cancer into remission?
What is it worth to turn back the clock and be healthy and full of life again?

Health Optimization Programs with Dr. Myatt: Affordable.
Good Health: PRICELESS.

Book A Brief Consultation Here To Get Started

Learn More About Consulting With Dr. Myatt Including “The Ultimate House Call”!

References

1.) CIA World Factbook accessed 10-29-10. https://www.cia.gov/library/publications/the-world-factbook/rankorder/2102rank.html
2.) Flegal, KM, Carroll, MD, Ogden, CL, Curtin, LR. Prevalence and Trends in Obesity Among US Adults, 1999–2008. Journal of the American Medical Association. 2010; 235–241.

Macular Degeneration


Age-Related Macular Degeneration (AMD)

Age-related macular degeneration (AMD) is a disease that gradually destroys sharp, central vision. Central vision is needed for seeing objects clearly and for common daily tasks such as reading and driving. AMD affects the macula, the part of the eye that allows you to see fine detail. AMD causes no pain.

In this simulation, how a person with AMD sees the world is presented graphically. As the disease progresses the area of central vision deteriorates. The gradual destruction of light sensitive cells continues until large areas are totally lost. Peripheral vision remains, but the ability to clearly see straight ahead is gradually lost. Credit: National Eye Institute, National Institutes of Health

In some cases, AMD advances so slowly that people notice little change in their vision. In others, the disease progresses faster and may lead to a loss of vision in both eyes. AMD is a leading cause of vision loss in Americans 60 years of age and older.

Wet AMD versus dry AMD

Wet AMD occurs when abnormal blood vessels behind the retina start to grow under the macula. These new blood vessels tend to be very fragile and often leak blood and fluid. The blood and fluid raise the macula from its normal place at the back of the eye. Damage to the macula occurs rapidly.

With wet AMD, loss of central vision can occur quickly. Wet AMD is also known as advanced AMD. It does not have stages like dry AMD.

An early symptom of wet AMD is that straight lines appear wavy. If you notice this condition or other changes to your vision, contact your eye care professional at once. You need a comprehensive dilated eye exam.

Dry AMD occurs when the light-sensitive cells in the macula slowly break down, gradually blurring central vision in the affected eye. As dry AMD gets worse, you may see a blurred spot in the center of your vision. Over time, as less of the macula functions, central vision is gradually lost in the affected eye.

The most common symptom of dry AMD is slightly blurred vision. You may have difficulty recognizing faces. You may need more light for reading and other tasks. Dry AMD generally affects both eyes, but vision can be lost in one eye while the other eye seems unaffected.
 

Normal vision and the same scene as viewed by a person with age-related macular degeneration. Normal vision
Normal vision   The same scene as viewed by a person with age-related macular degeneration
The same scene as viewed by a person with age-related macular degeneration

Causes and Risk Factors

Who is at risk for AMD?

The greatest risk factor is age. Although AMD may occur during middle age, studies show that people over age 60 are clearly at greater risk than other age groups. For instance, a large study found that people in middle-age have about a 2 percent risk of getting AMD, but this risk increased to nearly 30 percent in those over age 75.

Other risk factors include:

  • Smoking. Smoking may increase the risk of AMD.
  • Obesity. Research studies suggest a link between obesity and the progression of early and intermediate stage AMD to advanced AMD.
  • Race. Whites are much more likely to lose vision from AMD than African Americans.
  • Family history. Those with immediate family members who have AMD are at a higher risk of developing the disease.
  • Gender. Women appear to be at greater risk than men.
  • Aspirin. A new study links daily aspirin use to an increased risk of macular degeneration.16

Can my lifestyle make a difference?

Diet and lifestyle can play a role in reducing your risk of developing AMD.

  • Eat a diet high in green leafy vegetables and fish.
  • Don’t smoke.
  • Avoid daily aspirin use.16

Conventional Medical Treatment for Macular Degeneration

Wet AMD can be treated with laser surgery, photodynamic therapy, and injections into the eye. None of these treatments is a cure for wet AMD. The disease and loss of vision may progress despite treatment.

  1. Laser surgery. This procedure uses a laser to destroy the fragile, leaky blood vessels. A high energy beam of light is aimed directly onto the new blood vessels and destroys them, preventing further loss of vision. However, laser treatment may also destroy some surrounding healthy tissue and some vision. Only a small percentage of people with wet AMD can be treated with laser surgery. Laser surgery is more effective if the leaky blood vessels have developed away from the fovea, the central part of the macula. (See illustration at the beginning of this document.) Laser surgery is performed in a doctor’s office or eye clinic.

    The risk of new blood vessels developing after laser treatment is high. Repeated treatments may be necessary. In some cases, vision loss may progress despite repeated treatments.

     

  2. Photodynamic therapy. A drug called verteporfin is injected into your arm. It travels throughout the body, including the new blood vessels in your eye. The drug tends to “stick” to the surface of new blood vessels. Next, a light is shined into your eye for about 90 seconds. The light activates the drug. The activated drug destroys the new blood vessels and leads to a slower rate of vision decline. Unlike laser surgery, this drug does not destroy surrounding healthy tissue. Because the drug is activated by light, you must avoid exposing your skin or eyes to direct sunlight or bright indoor light for five days after treatment.

    Photodynamic therapy is relatively painless. It takes about 20 minutes and can be performed in a doctor’s office.

    Photodynamic therapy slows the rate of vision loss. It does not stop vision loss or restore vision in eyes already damaged by advanced AMD. Treatment results often are temporary. You may need to be treated again.

     

  3. Injections. Wet AMD can now be treated with new drugs that are injected into the eye (anti-VEGF therapy). Abnormally high levels of a specific growth factor occur in eyes with wet AMD and promote the growth of abnormal new blood vessels. This drug treatment blocks the effects of the growth factor.

    You will need multiple injections that may be given as often as monthly. The eye is numbed before each injection. After the injection, you will remain in the doctor’s office for a while and your eye will be monitored. This drug treatment can help slow down vision loss from AMD and in some cases improve sight.

Nutritional Treatment of Age-Related Eye Disease Study (AREDS)

Age-Related Eye Disease Study (AREDS)

The National Eye Institute’s Age-Related Eye Disease Study (AREDS) found that taking a specific high-dose formulation of antioxidants and zinc reduces the risk of advanced AMD and its associated vision loss by 25%, slowing AMD’s progression from the intermediate stage to the advanced stage.

 The specific daily amounts of antioxidants and zinc used by the study researchers were 500 milligrams of vitamin C, 400 International Units of vitamin E, 15 milligrams of beta-carotene (often labeled as equivalent to 25,000 International Units of vitamin A), 80 milligrams of zinc as zinc oxide, and two milligrams of copper as cupric oxide. Copper was added to the AREDS formulation containing zinc to prevent copper deficiency anemia, a condition associated with high levels of zinc intake.

Can diet alone provide the same high levels of antioxidants and zinc as the AREDS formulation?

No. The high levels of vitamins and minerals are difficult to achieve from diet alone. However, previous studies have suggested that people who have diets rich in green leafy vegetables have a lower risk of developing AMD.

Can a daily multivitamin alone provide the same high levels of antioxidants and zinc as the AREDS formulation?

No. The formulation’s levels of antioxidants and zinc are considerably higher than the amounts in any daily multivitamin.

If you are already taking daily multivitamins and your doctor suggests you take the high-dose AREDS formulation, be sure to review all your vitamin supplements with your doctor before you begin. Because multivitamins contain many important vitamins not found in the AREDS formulation, you may want to take a multivitamin along with the AREDS formulation. For example, people with osteoporosis need to be particularly concerned about taking vitamin D, which is not in the AREDS formulation. 1

How to Make Vision Supplements Work Better

Many people who take the AERDS nutritional supplement formula do not benefit from it and the disease progresses. Only about 25% of study participants benefited. Also note that this formula often slows the advancement of the disease. Just because you don’t notice improvement doesn’t mean it isn’t working.

Some holistic physicians, myself included, have found that poor assimilation — especially a decrease of gastric acid function in the stomach — is an important factor in the development of AMD. No matter how many supplements one takes, if they are not assimilated, they are of no value.

It is probably no coincidence that the risk of AMD increases with age and so does the decline of stomach acid production. Contrary to popular belief, most people who experience “heartburn” actually have too little stomach acid, not too much. Find out how that happens in this article: What’s Burning You?

So, in addition to taking eye nutrients, improving digestion and assimilation is also highly recommended.

Dr. Myatt’s Recommendations for Macular Degeneration

  1. Diet: eat a diet high in antioxidant nutrients (especially green vegetables), high in Omega-3 fatty acids (from fish) and low in Omega-6 fatty acids.
  2. Gastric function: Perform a Gastric Acid Self-Test or ask your holistic physician to perform a Heidleberg gastric analysis. Make corrections to gastric acid function as indicated by the test.
  3. Vision supplements: The following are specifically recommended for macular degeneration:

    I) Maxi Multi– optimal potency multiple vitamin / mineral / trace mineral supplement. 3 caps, 3 times per day with meals.

    Vision was the same or better in 88% of people with AMD who took a multiple vitamin / mineral supplement compared with 59% of those who those who did not take the supplement. This is a statistically significant difference. The supplement used in this study contained beta-carotene, vitamin C, vitamin E, zinc, copper, manganese, selenium, and riboflavin. 2  Other studies have confirmed the importance of vitamins A, C, E, zinc and other nutrients found in a quality multiple vitamin/ mineral formula. 3,5 More recent studies have also shown the importance of B complex vitamins in AMD.4

    II.) Maxi Marine O-3: (high potency fish oil). 1 cap, 2 times per day. A diet high in omega-3 fatty acids, especially from fish oil, has been associated with lower risk of macular degeneration in multiple studies. 5-10

    III.)  Lutein Plus (lutein and zeaxanthin).  1 cap, 1-2 times per day with meals. Lutein and zeaxanthin are two carotenoids that act directly in the macula to protect it from damaging effects of excess light.  Along with vitamins C and E, they are part of the antioxidant defense system of the macula.11      

    Studies have shown that lutein and zeaxanthin reduce the risk of AMD and may slow progression. 3-5, 11-14
    Smokers have an increased need for these carotenoids. 14      

How Long to See Results?

One study suggests that it takes at least 6 months of supplementation to see results. 15
 


References

  1. www.nei.nih.gov
  2. Olson RJ. Supplemental dietary antioxidant vitamins and minerals in patients with macular degeneration. J Am Coll Nutr 1991;10:550.
  3. Krishnadev N, Meleth AD, Chew EY. Nutritional supplements for age-related macular degeneration. Curr Opin Ophthalmol. 2010 May;21(3):184-9.
  4. Olson JH, Erie JC, Bakri SJ. Nutritional supplementation and age-related macular degeneration. Semin Ophthalmol. 2011 May; 26(3):131-6.
  5. Ho L, van Leeuwen R, Witteman JC, van Duijn CM, Uitterlinden AG, Hofman A, de Jong PT, Vingerling JR, Klaver CC. Reducing the genetic risk of age-related macular degeneration with dietary antioxidants, zinc, and ω-3 fatty acids: the Rotterdam study. Arch Ophthalmol. 2011 Jun;129(6):758-66.
  6. Mance TC, Kovacević D, Alpeza-Dunato Z, Stroligo MN, Brumini G. The role of omega 6 to omega 3 ratio in development and progression of age-related macular degeneration.Coll Antropol. 2011 Sep;35 Suppl 2:307-10.
  7. Merle B, Delyfer MN, Korobelnik JF, Rougier MB, Colin J, Malet F, Féart C, Le Goff M, Dartigues JF, Barberger-Gateau P, Delcourt C. Dietary omega-3 fatty acids and the risk for age-related maculopathy: the Alienor Study. Invest Ophthalmol Vis Sci. 2011 Jul 29;52(8):6004-11. Print 2011 Jul.
  8. Sangiovanni JP, Agrón E, Meleth AD, Reed GF, Sperduto RD, Clemons TE, Chew EY; Age-Related Eye Disease Study Research Group. {omega}-3 Long-chain polyunsaturated fatty acid intake and 12-y incidence of neovascular age-related macular degeneration and central geographic atrophy: AREDS report 30, a prospective cohort study from the Age-Related Eye Disease Study. Am J Clin Nutr. 2009 Dec;90(6):1601-7. Epub 2009 Oct 7.
  9. SanGiovanni JP, Chew EY, Agrón E, Clemons TE, Ferris FL 3rd, Gensler G, Lindblad AS, Milton RC, Seddon JM, Klein R, Sperduto RD; Age-Related Eye Disease Study Research Group. The relationship of dietary omega-3 long-chain polyunsaturated fatty acid intake with incident age-related macular degeneration: AREDS report no. 23. Arch Ophthalmol. 2008 Sep;126(9):1274-9.
  10. Seddon JM, Rosner B, Sperduto RD, Yannuzzi L, Haller JA, Blair NP, Willett W. Dietary fat and risk for advanced age-related macular degeneration. Arch Ophthalmol. 2001 Aug;119(8):1191-9.
  11. Fletcher AE. Free radicals, antioxidants and eye diseases: evidence from epidemiological studies on cataract and age-related macular degeneration. Ophthalmic Res. 2010;44(3):191-8. Epub 2010 Sep 9.
  12. SanGiovanni JP, Chew EY, Clemons TE, Ferris FL 3rd, Gensler G, Lindblad AS, Milton RC, Seddon JM, Sperduto RD. The relationship of dietary carotenoid and vitamin A, E, and C intake with age-related macular degeneration in a case-control study: AREDS Report No. 22.  Arch Ophthalmol. 2007 Sep;125(9):1225-32.
  13. Tan JS, Wang JJ, Flood V, Rochtchina E, Smith W, Mitchell P. Dietary antioxidants and the long-term incidence of age-related macular degeneration: the Blue Mountains Eye Study.Ophthalmology. 2008 Feb;115(2):334-41. Epub 2007 Jul 30.
  14. Schweigert FJ, Reimann J. [Micronutrients and their relevance for the eye–function of lutein, zeaxanthin and omega-3 fatty acids]. Klin Monbl Augenheilkd. 2011 Jun;228(6):537-43. Epub 2010 Aug 25.
  15. Cangemi FE. TOZAL Study: an open case control study of an oral antioxidant and omega-3 supplement for dry AMD. BMC Ophthalmol. 2007 Feb 26;7:3.
  16. Paulus T.V.M. de Jong, Usha Chakravarthy, Mati Rahu, Johan Seland, Gisele Soubrane, Fotis Topouzis, Johannes R. Vingerling, Jesus Vioque, Ian Young, Astrid E. Fletcher. Associations between Aspirin Use and Aging Macula Disorder:The European Eye Study. Ophthalmology Volume 119, Issue 1 , Pages 112-118, January 2012

 

Niacinamide (B3)

Potent Natural Help for Arthritis, Alzheimer’s, Anxiety and Type I Diabetes

Niacinamide, also known as nicotinamide and nicotinic acid amide, is a form of vitamin B3 (the other form is niacin).

Niacin is converted to into nicotinamide in the body, but these two different forms of B3 have slightly different effects. Niacinamide does not lower cholesterol or cause the flushing that niacin does.(1)

Consider Niacinamide for:

  • Osteoarthritis – niacinamide has been shown to improve joint mobility, reduce inflammation and allow for a decrease in arthritis medication.(2,3)
  • Alzheimer’s disease – a recent study found that niacinamide completely reverses symptoms of the disease in lab animals (4), and human trial are now under way. (5)
  • Memory improvement – The findings were so dramatic in the Alzheimer’s study that researchers suggest that even people with non-Alzheimer’s memory changes may benefit.(5)
  • Diabetes Type I- niacinamide reduces glycosylated hemoglobin, retards beta cell death (beta cells produce insulin) and helps prevent cell damage by restoring NAD levels.(6-8)
  • Anxiety and Stress – niacinamide has benzodiazepine-like actions which help balance brain chemistry and relieve anxiety. Study participants also reported better sleep with niacinamide.(9-10)


Dr. Myatt’s comment:
Although Big Pharma always tells us to “wait for more research” (which really means, “wait until we can figure out how to patent this as a drug”), I personally would not delay in starting niacinamide for early memory changes. The sooner corrective treatment is started, the greater the likelihood that it will help.

Niacinamide has been used safely since the 1940’s for arthritis and memory loss and it has an excellent safety profile.

Suggested dose: 1,000mg, 3 times per day with meals
Although it is rare, if this dose causes stomach upset, reduce to 500mg, 3 times per day and consult an holistic physician for guidance.

In both arthritis and memory loss, effects of niacinamide typically take 3-4 weeks to appear and 3-4 months to reach full effect.

References

1.) P Jaconello. Niacin versus niacinamide.CMAJ. 1992 October 1; 147(7): 990.
2.) Jonas WB, Rapoza CP, Blair WF. The effect of niacinamide on osteoarthritis: a pilot study. Inflamm Res. 1996 Jul;45(7):330-4.
3.) McCarty MF, Russell AL. Niacinamide therapy for osteoarthritis–does it inhibit nitric oxide synthase induction by interleukin 1 in chondrocytes? Med Hypotheses. 1999 Oct;53(4):350-60.
4.) Green KN, Steffan JS, Martinez-Coria H, et al. “ Nicotinamide restores cognition in Alzheimer’s disease transgenic mice via a mechanism involving sirtuin inhibition and selective reduction of Thr231-phosphotau.”J Neurosci 2008; 28(45): 11,500-11,510
5.) “Vitamin pill that may slow Alzheimer’s goes on trial,” The Guardian
(www.guardian.co.uk), 11/5/08
6.) Kolb H, Bukart V: Nicotinamide in type 1 diabetes. Mechanism of action revisited. Diabetes Care 1999 Mar;22 Suppl 2:B16-20
7.) Pozzilli P, Visalli N, Ghirlanda G, Manna R, Andreani D; Nicotinamide increases C-peptide secretion in patients with recent onset type 1 diabetes. Diabet Med 1989 Sep-Oct;6(7):568-72
8.) Vague P, Vialettes B, Lassmann-Vague V, Vallo J; Nicotinamide may extend remission phase of insulin-dependent diabetes. The Lancet Mar 1987 ltr
9.) Akhundov RA, Sultanov AA, Gadzhily RA, Sadykhov RV; [Psychoregulating role of nicotinamide]. Biull Eksp Biol Med 1993 May;115(5):487-91.
10.) Mohler H, Pole P, Cumin R, Pieri L, Kettler R; Nicotinamide is a brain constituent with benzodiazepine-like actions. Nature 1979 Apr 5;278(5704):563-5.

Turmeric:


Powerful Cancer-fighting Herb
that drug companies are rushing to imitate.

An ever-growing body of scientific evidence demonstrates that turmeric — the bright yellow spice herb used in East Indian cooking — has potent anti-cancer properties. According to Bharat Aggarwal, chief of cytokine research at the University of Texas M.D. Anderson Cancer Center, the research to date shows that turmeric’s anti-cancer “promise is enormous.” This evidence and opinion was reported at the recent Society for Integrative Oncology conference and is also posted on the American Cancer Society’s website (www.cancer.org).

Turmeric, and it’s primary active ingredient curcumin, is the main ingredient in curry and a member of the ginger family. In addition to it’s anti-cancer properties, turmeric is a potent antioxidant, anti-inflammatory and liver-protecting herb. Expect to see and read a lot more about this herb in the future, although Wellness Club members have known about the benefits of turmeric for over a decade!

You can learn more about turmeric and find one of the most potent turmeric supplements available on The Wellness Club website by visiting Turmeric: Antioxidant, Anti-inflammatory and Anti-Cancer Herb.

References

1.) Curcumin inhibits the mammalian target of rapamycin-mediated signaling pathways in cancer cells. Beevers,Li,Liu,Huang. Int J Cancer. 2006 Mar 20
2.) Antitumor action of curcumin in human papillomavirus associated cells involves downregulation of viral oncogenes, prevention of NFkB and AP-1 translocation, and modulation of apoptosis. Divya CS, Pillai MR. Mol Carcinog. 2006 May;45(5):320-32.
3.) Curcumin mediates ceramide generation via the de novo pathway in colon cancer cells. Moussavi M, Assi K, Gomez-Munoz A, Salh B. Carcinogenesis. 2006 Feb 25; [Epub ahead of print]
4.) Overexpression of p65/RelA potentiates curcumin-induced apoptosis in HCT116 human colon cancer cells. Collett GP, Campbell FC. Carcinogenesis. 2006 Feb 23; [Epub ahead of print]
5.) Induction of G2/M arrest and inhibition of cyclooxygenase-2 activity by curcumin in human bladder cancer T24 cells. Park C, Kim GY, Kim GD, Choi BT, Park YM, Choi YH. Oncol Rep. 2006 May;15(5):1225-31.
6.) Molecular targets of dietary agents for prevention and therapy of cancer. Aggarwal BB, Shishodia S. Biochem Pharmacol. 2006 Feb 23; [Epub ahead of print]
7.) Inhibition of telomerase activity and induction of apoptosis by curcumin in K-562 cells. Chakraborty S, Ghosh U, Bhattacharyya NP, Bhattacharya RK, Roy M. Mutat Res. 2006 Jan 27; [Epub ahead of print]
8.) Curcumin differentially sensitizes malignant glioma cells to TRAIL/Apo2L-mediated apoptosis through activation of procaspases and release of cytochrome c from mitochondria. Gao X, Deeb D, Jiang H, Liu YB, Dulchavsky SA, Gautam SC. J Exp Ther Oncol. 2005;5(1):39-48.
9.) Multiple biological activities of curcumin: a short review. Maheshwari RK, Singh AK, Gaddipati J, Srimal RC. Life Sci. 2006 Mar 27;78(18):2081-7. Epub 2006 Jan 18.
10.) Curcumin, an atoxic antioxidant and natural NFkappaB, cyclooxygenase-2, lipooxygenase, and inducible nitric oxide synthase inhibitor: a shield against acute and chronic diseases. Bengmark S. JPEN J Parenter Enteral Nutr. 2006 Jan-Feb;30(1):45-51.
11.) Antiproliferation and apoptosis induced by curcumin in human ovarian cancer cells. Shi M, Cai Q, Yao L, Mao Y, Ming Y, Ouyang G. Cell Biol Int. 2006 Mar;30(3):221-6. Epub 2005 Dec 22.
12.) Synergistic inhibitory effects of curcumin and 5-fluorouracil on the growth of the human colon cancer cell line HT-29. Du B, Jiang L, Xia Q, Zhong L. Chemotherapy. 2006;52(1):23-8. Epub 2005 Dec 9.
13.) Curcumin induces human HT-29 colon adenocarcinoma cell apoptosis by activating p53 and regulating apoptosis-related protein expression. Song G, Mao YB, Cai QF, Yao LM, Ouyang GL, Bao SD. Braz J Med Biol Res. 2005 Dec;38(12):1791-8. Epub 2005 Nov 9.
14.) Inhibition of cellular proliferation and induction of apoptosis by curcumin in human malignant astrocytoma cell lines. Nagai S, Kurimoto M, Washiyama K, Hirashima Y, Kumanishi T, Endo S. J Neurooncol. 2005 Sep;74(2):105-11.
15.) Curcumin inhibits human colon cancer cell growth by suppressing gene expression of epidermal growth factor receptor through reducing the activity of the transcription factor Egr-1. Chen A, Xu J, Johnson AC. Oncogene. 2006 Jan 12;25(2):278-87.

 

 

Argyria

A Bluish Discoloration Of Tissues (esp. Skin) Due To Silver

Regarding reports of silver turning skin blue in humans:

It is certainly possible to over-ingest silver-containing solutions abd cause a permanant bluish discoloration of skin and other tissues. To achieve this effect requires massive ingestion of silver far in excess of anything therapeutic or sensible.

The following information comes from Wikipedia:

A prominent case was that of Stan Jones of Montana, a Libertarian candidate for the United States Senate in 2002 and 2006. Jones acquired argyria through consumption of a home-made silver product that he made due to fears that the Year 2000 problem would make antibiotics unavailable. The peculiar colouration of his skin was featured prominently in media coverage of his unsuccessful campaign, though Jones contends that the best-known photo was “doctored”. Jones promised that he was not using his silvery complexion as a gimmick. He continues to promote the use of colloidal silver as a home remedy. He has said that his good health, minus the unusual skin tone, is the result of his use of colloidal silver.

On December 20, 2007 the world press published stories about Paul Karason, a California man whose entire skin gradually turned blue after consuming colloidal silver made by himself with distilled water, salt and silver, and using a silver salve on his face in an attempt to treat problems with his sinus, dermatitis, acid reflux, and other issues. This happened because he drank gallons of colloidal silver per week for years.

In our opinion, neither of the cases cited above represents sensible or prudent use of colloidal silver – in fact there is ample evidence that the home-made soludions used by these two persons are not in fact true colloidal suspensions!

Silver has a long and honorable history of use in human healing. There is ample literature attesting to it’s safety and efficacy. Here is an abstract from just one article:

Silver has a long and intriguing history as an antibiotic in human health care. It has been developed for use in water purification, wound care, bone prostheses, reconstructive orthopaedic surgery, cardiac devices, catheters and surgical appliances. Advancing biotechnology has enabled incorporation of ionizable silver into fabrics for clinical use to reduce the risk of nosocomial infections and for personal hygiene. The antimicrobial action of silver or silver compounds is proportional to the bioactive silver ion (Ag(+)) released and its availability to interact with bacterial or fungal cell membranes. Silver metal and inorganic silver compounds ionize in the presence of water, body fluids or tissue exudates. The silver ion is biologically active and readily interacts with proteins, amino acid residues, free anions and receptors on mammalian and eukaryotic cell membranes. Bacterial (and probably fungal) sensitivity to silver is genetically determined and relates to the levels of intracellular silver uptake and its ability to interact and irreversibly denature key enzyme systems. Silver exhibits low toxicity in the human body, and minimal risk is expected due to clinical exposure by inhalation, ingestion, dermal application or through the urological or haematogenous route. Chronic ingestion or inhalation of silver preparations (especially colloidal silver) can lead to deposition of silver metal/silver sulphide particles in the skin (argyria), eye (argyrosis) and other organs. These are not life-threatening conditions but cosmetically undesirable. Silver is absorbed into the human body and enters the systemic circulation as a protein complex to be eliminated by the liver and kidneys. Silver metabolism is modulated by induction and binding to metallothioneins. This complex mitigates the cellular toxicity of silver and contributes to tissue repair. Silver allergy is a known contra-indication for using silver in medical devices or antibiotic textiles.

Reference

Lansdown AB (2006). “Silver in health care: antimicrobial effects and safety in use”. Current Problems in Dermatology 33: 17–34. http://www.ncbi.nlm.nih.gov/pubmed/16766878

Longevity Lab Profile

Dr. Myatt’s Longevity Lab Profile

Americans LOVE medical tests. This isn’t just my professional opinion after twenty–three years in practice, it has been proven. In fact, we spend more on medical testing than any other country in the world

In spite of all the “looking” and testing, the average American lifespan is 78 years, 11 years behind the longest-lived industrial nation and 51st in the world.(33) All our testing isn’t helping us live longer or even better. Much of this testing is a bust.

So, am I recommending that we forgo ALL medical testing? Heck no! A simple chemistry screen and CBC (complete blood count) annually can tell us a lot about one’s general state of health and help us make early “course changes” to avoid problem. I always recommend these simple tests annually. They are inexpensive and easy, “cheap health insurance” in my opinion. I get mine done twice per year.

However, in examining the scientific literature and looking for the most important markers to follow, there are several tests that emerge as being true “longevity markers.” These tests have an “optimal range” that is smaller (tighter) than the conventional medical range. Stay within that range, and your risk of “all cause mortality” is dramatically diminished.

SO, on that note, I present the simple collection of tests that I consider an indispensable part of an anti-aging / longevity program.

1.) hgA1C optimal range: 5.0-5.4

Hemoglobin A1C is a measure of the amount of hemoglobin’s exposure to plasma glucose. It is now considered the “Gold Standard” for monitoring blood sugar levels because it reflects what the average blood sugar levels have been for the preceding three months or so.

Conventional reference ranges are typically 4.0-5.6, with 5.6-6.4 considered “pre diabetes.” However, one large study found that an hgA1C outside the 5.0-5.4 range was associated with an increased risk of death from all causes. This is called “all cause mortality.” (1)

2.) TSH optimal: 0.5-1.4 (check thyroid hormones below 0.5 to evaluate for hyperthyroid)

Thyroid Stimulating Hormone is a measure of the amount of TSH that is being put out by the pituitary gland in order to stimlate thyroid hormone output. In conventional medicine, it is considered the “Gold Standard” screen test for thyroid function.

I have actually seen many patients with abnormal thyroid hormone levels (free T3 and free T4) who had normal TSH levels. I have also seen patients with abnormal TSH levels who had normal thyroid hormone levels. This makes me question TSH’s “Gold Standard” position as the best screen for thyroid hormones. I personally prefer to also test the thyroid hormones directly the first time I evaluate thyroid function. I also look at “reverse T3” which can block thyroid utilization even in the presence of normal thyroid levels. But, I digress.

The standard “normal” range for TSH on lab tests is about 0.5 to 4.6 mIU/L. This range reflects two standard deviations around the US mean, meaning that 95% of the population falls in the “normal” range. Unfortunately, there is no evidence that TSH values in this range are health or normal.  In fact, many people with “normal” TSH live with symptoms of hypothyroidism.

Research demonstrating that many people are thyroid-deficient and that improving thyroid status can dramatically improve health has been conducted in Europe:

The HUNT study of 25,000 healthy Norwegians found that those with a TSH level of 1.5 to 2.4 were 41% more likely to die over the next 8 years than those with TSH below 1.5; those with TSH 2.5-3.4 were 69% more likely to die.(2)

3.) hs-CRP (highly sensitive C-reactive protein). Optimal range <1.3.

Inflammation is recognized as an important mechanism of cardiovascular injury. Subtle inflammation as measured by hs-CRP, is highly associated with heart disease risk and with an increased risk of death from all causes. (3-19)

It should be noted that hs-CRP was an “emerging risk factor” back in 1998 when I first reported on it in HealthBeat. Many physicians had not even heard of the test, including cardiologists. I advised my patients to get the test even though it wasn’t yet covered by insurance. Today, ordering an hs-CRP is “standard of care” and a routine part of most conventional cardiac risk profiles. But it should also be a routine anti-aging marker since it is associated with all-cause mortality.

4.) Ferritin optimal range 25-80; slightly < 50 may be ideal.

Ferritin is an iron storage protein and is a measure of  body iron stores. High (even “high normal”) iron levels increase free radical production and are highly associated with increased risk of atherosclerosis and peripheral vascular disease. Serum ferritin was one of the strongest risk predictors of overall progression of atherosclerosis. (20-29)

5.) Vitamin D (optimal range: 50-60 nmol/liter)

There is a strong association between vitamin D levels and all-cause mortality. All-cause mortality was 26% higher among those in the lowest vitamin D quartile compared with those in the highest quartile with optimal vitamin D status above 32.1 ng/mL after controlling for baseline demographics. (30-32)

This Panel INCLUDES all tests of the Opti-Plus Profile

N402 – Longevity Lab Profile – 273.00

Enter Quantity Desired and Click “Add To Cart” Button

References

  1. Carson AP, Fox CS, McGuire DK, Levitan EB, Laclaustra M, Mann DM, Muntner P.Carson AP, Fox CS, McGuire DK, Levitan EB, Laclaustra M, Mann DM, Muntner P. Low hemoglobin A1c and risk of all-cause mortality among US adults without diabetes. Circ Cardiovasc Qual Outcomes. 2010 Nov;3(6):661-7. doi: 10.1161/CIRCOUTCOMES.110.957936. Epub 2010 Oct 5.
  2. Asvold BO et al. Thyrotropin levels and risk of fatal coronary heart disease: the HUNT study. Arch Intern Med. 2008 Apr 28;168(8):855-60. http://pmid.us/18443261.
  3. Yeh ET. High-sensitivity C-reactive protein as a risk assessment tool for cardiovascular disease.Clin Cardiol. 2005 Sep;28(9):408-12.
  4. Paoletti R, Bolego C, Poli A, Cignarella A. Metabolic syndrome, inflammation and atherosclerosis. Vasc Health Risk Manag. 2006;2(2):145-52.
  5. Comparison of C-reactive protein and low-density lipoprotein cholesterol levels in the prediction of first Cardiovascular events. N Engl J Med. 2002 Nov 14;347(20):1557-65.
  6. Association of serum C-reactive protein and LDL:HDL with myocardial infarction. J Pak Med Assoc. 2006 Jul;56(7):318-22.
  7. Barac A, Wang H, Shara NM, de Simone G, Carter EA, Umans JG, Best LG, Yeh J, Dixon DB, Devereux RB, Howard BV, Panza JA. Markers of inflammation, metabolic risk factors, and incident heart failure in American Indians: the Strong Heart Study. J Clin
  8. Clearfield MB. C-reactive protein: a new risk assessment tool for cardiovascular disease. J Am Osteopath Assoc. 2005 Sep;105(9):409-16.
  9. Goicoechea M, de Vinuesa SG, Gómez-Campderá F, Aragoncillo I, Verdalles U, Mosse A, Luño J. Serum fibrinogen levels are an independent predictor of mortality in patients with chronic kidney disease (CKD) stages 3 and 4. Kidney Int Suppl. 2008 Dec;(111):S67-70.
  10. Gotto AM Jr. Role of C-reactive protein in coronary risk reduction: focus on primary prevention.Am J Cardiol. 2007 Mar 1;99(5):718-25. Epub 2007 Jan 10
  11. Kalogeropoulos A, Georgiopoulou V, Psaty BM, Rodondi N, Smith AL, Harrison DG, Liu Y, Hoffmann U, Bauer DC, Newman AB, Kritchevsky SB, Harris TB, Butler J; Health ABC Study Investigators. Inflammatory markers and incident heart failure risk in older adults: the Health ABC (Health, Aging, and Body Composition) study. J Am Coll Cardiol. 2010 May 11;55(19):2129-37.
  12. Ridker PM, Stampfer MJ, Rifai N. Novel risk factors for systemic atherosclerosis: a comparison of C-reactive protein, fibrinogen, homocysteine, lipoprotein(a), and standard cholesterol screening as predictors of peripheral arterial disease. JAMA. 2001 May 16;285(19):2481-5.
  13. Libby P. Inflammation and cardiovascular disease mechanisms. Am J Clin Nutr. 2006 Feb;83(2):456S-460S.
  14. Mora S, Rifai N, Buring JE, Ridker PM. Additive value of immunoassay-measured fibrinogen and high-sensitivity C-reactive protein levels for predicting incident cardiovascular events. Circulation. 2006 Aug 1;114(5):381-7. Epub 2006 Jul 24.
  15. Munk PS, Larsen AI. Inflammation and C-reactive protein in cardiovascular disease. Tidsskr Nor Laegeforen. 2009 Jun 11;129(12):1221-4.
  16. Onat A, Can G, Hergenç G. Serum C-reactive protein is an independent risk factor predicting cardiometabolic risk. Metabolism. 2008 Feb;57(2):207-14.
  17. Ridker PM, Rifai N, Cook NR, Bradwin G, Buring JE. Non-HDL cholesterol, apolipoproteins A-I and B100, standard lipid measures, lipid ratios, and CRP as risk factors for cardiovascular disease in women. JAMA. 2005 July 20;294(3):326-33.
  18. Shlipak MG, Ix JH, Bibbins-Domingo K, Lin F, Whooley MA. Biomarkers to predict recurrent cardiovascular disease: the Heart and Soul Study. Am J Med. 2008 Jan;121(1):50-7.
  19. Yu H, Rifai N. High-sensitivity C-reactive protein and atherosclerosis: from theory to therapy. Clin Biochem. 2000 Nov;33(8):601-10.
  20. Alissa EM, Ahmed WH, Al-Ama N, Ferns GA. Relationship between indices of iron status and coronary risk factors including diabetes and the metabolic syndrome in Saudi subjects without overt coronary disease. J Trace Elem Med Biol. 2007;21(4):242-54. Epub 2007 Aug 7
  21. Ahluwalia N, Genoux A, Ferrieres J, Perret B, Carayol M, Drouet L, Ruidavets JB. Iron status is associated with carotid atherosclerotic plaques in middle-aged adults. J Nutr. 2010 Apr;140(4):812-6. Epub 2010 Feb 24.
  22. de Godoy MF, Takakura IT, Machado RD, Grassi LV, Nogueira PR. Serum ferritin and obstructive coronary artery disease: angiographic correlation. Arq Bras Cardiol. 2007 Apr;88(4):430-3.
  23. Depalma RG, Hayes VW, Chow BK, Shamayeva G, May PE, Zacharski LR. Ferritin levels, inflammatory biomarkers, and mortality in peripheral arterial disease: a substudy of the Iron (Fe) and Atherosclerosis Study (FeAST) Trial. J Vasc Surg. 2010 Jun;51(6):1498-503. Epub 2010 Mar 20
  24. Kiechl S, Willeit J, Egger G, Poewe W, Oberhollenzer F.Body iron stores and the risk of carotid atherosclerosis: prospective results from the Bruneck study.Circulation. 1997 Nov 18;96(10):3300-7.
  25. Lee KR, Sweeney G, Kim WY, Kim KK. Serum ferritin is linked with aortic stiffness in apparently healthy Korean women. Crit Pathw Cardiol. 2010 Sep;9(3):160-3
  26. Mainous AG 3rd, Diaz VA. Relation of serum ferritin level to cardiovascular fitness among young men. Am J Cardiol. 2009 Jan 1;103(1):115-8. Epub 2008 Oct 17.
  27. Menke A, Fernández-Real JM, Muntner P, Guallar E. The association of biomarkers of iron status with peripheral arterial disease in US adults. BMC Cardiovasc Disord. 2009 Aug 3;9:34.
  28. Valenti L, Swinkels DW, Burdick L, Dongiovanni P, Tjalsma H, Motta BM, Bertelli C, Fatta E, Bignamini D, Rametta R, Fargion S, Fracanzani AL. Serum ferritin levels are associated with vascular damage in patients with nonalcoholic fatty liver disease. Nutr Metab Cardiovasc Dis. 2011 Aug;21(8):568-75. Epub 2010 Apr 13.
  29. Zacharski LR, Shamayeva G, Chow BK. Effect of controlled reduction of body iron stores on clinical outcomes in peripheral arterial disease. Am Heart J. 2011 Nov;162(5):949-957.
  30. Melamed ML, et al. 25-Hydroxyvitamin D Levels and the Risk of Mortality in the General Population. Arch Intern Med 2008; 168: 1629-1637.
  31. Saliba W, Barnett O, Rennert HS, Rennert G. The risk of all-cause mortality is inversely related to serum 25(OH)D levels. J Clin Endocrinol Metab. 2012 Aug;97(8):2792-8. doi: 10.1210/jc.2012-1747. Epub 2012 May 30.
  32. Durup D, Jørgensen HL, Christensen J, Schwarz P, Heegaard AM, Lind B. A reverse J-shaped association of all-cause mortality with serum 25-hydroxyvitamin D in general practice: the CopD study. J Clin Endocrinol Metab. 2012 Aug;97(8):2644-52. doi: 10.1210/jc.2012-1176. Epub 2012 May 9.
  33. CIA World Factbook: https://www.cia.gov/library/publications/the-world-factbook/rankorder/2102rank.html